Statistics and Data Analysis for Microarrays Using R and Bioconductor, 2/e (Hardcover)
暫譯: 使用 R 和 Bioconductor 進行微陣列的統計與數據分析,第 2 版 (精裝本)

Sorin Drăghici

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商品描述

Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that teaches students the basics of R and microarray technology as well as how to choose and apply the proper data analysis tool to specific problems.

New to the Second Edition
Completely updated and double the size of its predecessor, this timely second edition replaces the commercial software with the open source R and Bioconductor environments. Fourteen new chapters cover such topics as the basic mechanisms of the cell, reliability and reproducibility issues in DNA microarrays, basic statistics and linear models in R, experiment design, multiple comparisons, quality control, data pre-processing and normalization, Gene Ontology analysis, pathway analysis, and machine learning techniques. Methods are illustrated with toy examples and real data and the R code for all routines is available on an accompanying CD-ROM.

 

With all the necessary prerequisites included, this best-selling book guides students from very basic notions to advanced analysis techniques in R and Bioconductor. The first half of the text presents an overview of microarrays and the statistical elements that form the building blocks of any data analysis. The second half introduces the techniques most commonly used in the analysis of microarray data.

商品描述(中文翻譯)

豐富的彩色插圖,使用 R 和 Bioconductor 的微陣列統計與數據分析(第二版) 提供了一個清晰且嚴謹的描述,介紹了用於挖掘和解釋生物信息的強大分析技術和算法。省略繁瑣的細節、繁重的形式主義和晦澀的符號,該文本採取了實作為主、以範例為基礎的方法,教導學生 R 和微陣列技術的基本知識,以及如何選擇和應用適當的數據分析工具來解決特定問題。

第二版的新內容

這一時效性強的第二版完全更新,且是其前身的兩倍大小,取代了商業軟體,改為開源的 R 和 Bioconductor 環境。十四個新章節涵蓋了細胞的基本機制、DNA 微陣列中的可靠性和可重複性問題、R 中的基本統計和線性模型、實驗設計、多重比較、質量控制、數據預處理和標準化、基因本體分析、途徑分析以及機器學習技術。方法以玩具範例和真實數據進行說明,所有例程的 R 代碼可在隨附的 CD-ROM 上獲得。

包含所有必要的前提條件,這本暢銷書指導學生從非常基本的概念到 R 和 Bioconductor 中的高級分析技術。文本的前半部分概述了微陣列及其構成任何數據分析的統計元素。後半部分介紹了在微陣列數據分析中最常用的技術。