Protein-Protein Interactions: Pathophysiological and Therapeutic Aspects: Volume II

Poluri, Krishna Mohan, Gulati, Khushboo, Tripathi, Deepak Kumar

Protein-Protein Interactions: Pathophysiological and Therapeutic Aspects: Volume II
  • 出版商: Springer
  • 出版日期: 2024-08-19
  • 售價: $7,700
  • 貴賓價: 9.5 折 $7,315
  • 語言: 英文
  • 頁數: 428
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 9819924251
  • ISBN-13: 9789819924257

    • 海外代購書籍(需單獨結帳)

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商品描述

The second volume of the book-Protein-Protein Interactions (PPIs) provides an overview of various protein-protein interactions (PPIs) that are involved in various human diseases including cancer, neurodegenerative diseases, immune diseases, and inflammation. It summarizes the structure and ligand-based drug designing approaches for the discovery of small molecules that can inhibit PPIs in these diseases.

The book discusses different computational and experimental tools that are used to determine the anomalous interactions underlying the diseases.

Lastly, it also reviews the classical interactions between pathogens and hosts that are responsible for the pathophysiology of infectious diseases.

商品描述(中文翻譯)

本書第二卷《蛋白質-蛋白質相互作用（PPIs）》概述了涉及各種人類疾病的蛋白質-蛋白質相互作用，包括癌症、神經退行性疾病、免疫疾病和炎症。它總結了基於結構和配體的藥物設計方法，以發現能夠抑制這些疾病中PPIs的小分子。

本書討論了用於確定疾病背後異常相互作用的各種計算和實驗工具。

最後，它還回顧了病原體與宿主之間的經典相互作用，這些相互作用對傳染病的病理生理學負有責任。

作者簡介

Dr. Krishna Mohan Poluri is currently working as an Associate Professor at Department of Biosciences and Bioengineering, and Centre for Nanotechnology at Indian Institute of Technology Roorkee (IIT-Roorkee). Dr. Poluri completed his PhD from Tata Institute of Fundamental Research TIFR-Mumbai, and Post-doc from Rutgers University & University of Texas Medical Branch (UTMB-Texas). His areas of expertise are Protein Biochemistry & Biophysics, Bio-molecular Interactions, Structural Biology, Glycoimmunology, Bionanotechnology and Algal Biotechnology etc. He has published 160 publications including Research articles, editorials, books and book chapters in various reputed international Journals. Dr. Poluri is also a guest editor/editorial board member and adhoc reviewer for several international research journals. He won several awards and fellowships for his research work. Most prominent are: Ashok Soota institute research fellow (2021), Young scientist awards from Indian ScienceCongress association (ISCA) -2009, National Academy of Sciences India (NASI)-2014, and Innovative Young Biotechnologist Award (IYBA)-2013 by DBT.

Dr. Khushboo Gulati has completed her PhD in the area of "Protein Biophysics" at Department of Biosciences and Bioengineering, Indian Institute of Technology (IIT), Roorkee. Dr. Gulati completed her Bachelors in Bioinformatics and Masters in Biotechnology from Punjab University, India. Her Research interests are in the area of Protein-Protein Interactions, Protein Engineering, Molecular Biophysics, and Structural Biology. Dr. Gulati has authored around 20 peer reviewed publications in SCI indexed international journals, 4 book chapters and 2 books. Dr. Gulati is a recipient of ICMRBS young scientist award.

Mr. Deepak Kumar Tripathi is currently working as a Research Scholar at Mechanistic Biological Chemistry Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology (IIT), Roorkee.He has completed his Bachelor's in Biotechnology from Uttar Pradesh Technical University (UPTU), Lucknow, in 2014. Mr. Tripathi completed his Master's degree in Industrial Biotechnology from National Institute of Technology Karnataka (NITK), Surathkal, in 2017. His research interests are in the area of Protein Engineering, Protein-Ligand Interactions, Molecular Biophysics, and Structural Biology.

Ms. Nupur Nagar is currently working as a Research Scholar at Mechanistic Biological Chemistry Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology (IIT), Roorkee. Ms. Nagar completed her Master's degree in Plant Biotechnology from TERI University, New Delhi in 2017. Her research interest is in the protein engineering, structural biology, bioinformatics, and data analytics.


作者簡介(中文翻譯)

Dr. Krishna Mohan Poluri 目前擔任印度理工學院魯爾基分校 (IIT-Roorkee) 生物科學與生物工程系及奈米科技中心的副教授。Poluri 博士於塔塔基礎研究所 (TIFR-Mumbai) 獲得博士學位，並在羅格斯大學及德克薩斯大學醫學分校 (UTMB-Texas) 完成博士後研究。他的專業領域包括蛋白質生物化學與生物物理學、生物分子相互作用、結構生物學、糖免疫學、生物奈米科技及藻類生物技術等。他在各大國際期刊上發表了160篇論文，包括研究文章、社論、書籍及書籍章節。Poluri 博士同時擔任多個國際研究期刊的客座編輯、編輯委員會成員及臨時審稿人。他因其研究工作獲得多項獎項及獎學金，其中最著名的包括：阿肖克·蘇塔研究所研究獎學金 (2021)、印度科學大會 (ISCA) 年輕科學家獎 (2009)、印度科學院 (NASI) 獎 (2014) 及由 DBT 頒發的創新年輕生物技術獎 (IYBA) (2013)。

Dr. Khushboo Gulati 在印度理工學院魯爾基分校 (IIT) 生物科學與生物工程系完成了「蛋白質生物物理學」領域的博士學位。Gulati 博士於印度旁遮普大學獲得生物資訊學學士學位及生物技術碩士學位。她的研究興趣包括蛋白質-蛋白質相互作用、蛋白質工程、分子生物物理學及結構生物學。Gulati 博士在 SCI 索引的國際期刊上發表了約20篇同行評審的論文，並撰寫了4篇書籍章節及2本書籍。她是 ICMRBS 年輕科學家獎的獲得者。

Mr. Deepak Kumar Tripathi 目前擔任印度理工學院魯爾基分校 (IIT) 機制生物化學實驗室的研究學者。他於2014年在北方邦技術大學 (UPTU) 獲得生物技術學士學位，並於2017年在卡納塔克國立技術學院 (NITK) 獲得工業生物技術碩士學位。他的研究興趣包括蛋白質工程、蛋白質-配體相互作用、分子生物物理學及結構生物學。

Ms. Nupur Nagar 目前擔任印度理工學院魯爾基分校 (IIT) 機制生物化學實驗室的研究學者。Nagar 女士於2017年在德里 TERI 大學獲得植物生物技術碩士學位。她的研究興趣包括蛋白質工程、結構生物學、生物資訊學及數據分析。

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