Epigenetics of Infectious Diseases
暫譯: 傳染病的表觀遺傳學

Doerfler, Walter, Casadesus, Josep

  • 出版商: Springer
  • 出版日期: 2018-08-01
  • 售價: $6,930
  • 貴賓價: 9.5$6,584
  • 語言: 英文
  • 頁數: 277
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3319855468
  • ISBN-13: 9783319855462
  • 海外代購書籍(需單獨結帳)

商品描述

The present volume of Epigenetics and Human Health is devoted to the patho-epigenetics of viral and microbial infections, an exiting new field of disease-related epigenetic research. As recognized during the past years, epigenetic reprogramming of pathogen and host genome functions - the latter frequently induced by pathogens - plays an important role in many infectious processes. Beyond their immediate relevance for pathogen proliferation and obligatorily associated symptoms, such alterations frequently contribute to severe additional complications, such as the development of immunodeficiency, cancer and various chronic disorders. This holds in particular for epigenetic dysregulation of host gene expression induced by latent infections. The present book summarizes current knowledge of the mechanisms underlying epigenetic changes caused by viral, bacterial, fungal and protozoan infections and their impact on human health.

商品描述(中文翻譯)

本書《表觀遺傳學與人類健康》專注於病毒和微生物感染的病理表觀遺傳學,這是一個令人興奮的新興疾病相關表觀遺傳研究領域。近年來已經認識到,病原體和宿主基因組功能的表觀遺傳重編程——後者通常由病原體誘導——在許多感染過程中扮演著重要角色。除了對病原體增殖及其必然相關症狀的直接影響外,這些改變經常會導致嚴重的附加併發症,例如免疫缺陷、癌症和各種慢性疾病的發展。這一點尤其適用於由潛伏感染引起的宿主基因表達的表觀遺傳失調。本書總結了由病毒、細菌、真菌和原生動物感染引起的表觀遺傳變化的機制及其對人類健康的影響的最新知識。