Toxic Chemical and Biological Agents: Detection, Diagnosis and Health Concerns
暫譯: 有毒化學與生物劑:檢測、診斷與健康問題

Sindona, Giovanni, Banoub, Joseph H., Di Gioia, Maria Luisa

  • 出版商: Springer
  • 出版日期: 2020-10-20
  • 售價: $8,550
  • 貴賓價: 9.5$8,123
  • 語言: 英文
  • 頁數: 282
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 9402420401
  • ISBN-13: 9789402420401
  • 相關分類: 化學 Chemistry生物資訊 BioinformaticsData Science
  • 海外代購書籍(需單獨結帳)

商品描述

This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents.

In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.

商品描述(中文翻譯)

本書批判性地評估了有關新興及重要檢測技術的現狀,例如質譜(mass spectrometry)、串聯質譜(tandem mass spectrometry)、生物感測器檢測(biosensor detection)和組織成像(tissue imaging),這些技術與有毒化學和生物劑相關。

一般而言,主要討論的主題涉及化學和生物劑對人類健康的風險和後果,特別強調所有生化和代謝途徑,包括生殖系統。書中還討論了暴露組(exposome)、遺傳風險和環境、各種健康危害因子、風險評估、環境評估和應變準備,以及在分子層面分析亞致死效應。最後,本書提供了有關暴露診斷和與有毒化學及生物劑相關的健康問題的全面資訊。

作者簡介

Professor Giovanni Sindona from the Department of Chemistry, University of Calabria (Italy) died on Thursday January 16, 2020. We have lost a dear friend, a scholar and a gentleman. Giovanni was born in Messina, Italy in 9 April 1949 and graduated with a B.Sc. (Hons) Chemistry in 1972 at the University of Messina. After completing his PhD in applied to bioanalytical chemistry (mass spectrometry). In 1978, he was awarded he "Alexander von Humboldt foundation Fellowship" from the renowned Institute für Physikalische Chemie of Bonn University. At the beginning of the 80s, was as NATO scholar at the King's college of London under the direction of Professor Colin B. Reese where he developed new strategies for the synthesis of nucleic acids.

In 1990, he became full professor of organic chemistry at the university of Calabria teaching organic chemistry also at the University of Magna Graecia Catanzaro. In his academic career, he held important management offices: He was Dean of the Mathematics, Physics, and Natural Sciences faculty from 1994 to 1997. He directed the department of Chemistry from 1997 to 2003 and from 2007 to 2015 during the establishment of the former Department of Chemistry and Chemical Technologies

From 1990 to 2019, Prof Sindona has organized and directed five NATO International Schools for young researchers on the application of mass spectrometry to biomolecular chemistry held in Italy and abroad. In 2009, he became co-director of many NATO-ASI, Science for Peace and Security Program for experts on the Detection of Biological Agents and Toxins for the Prevention of Bioterrorism in Homeland Security.

Professor Sindona has been member of the Italian Society of Chemistry (SCI), where he was president of the Mass Spectrometry Division and coordinator of the inter divisional group of proteomic; he was president of the SCI Calabria section, and from 1979 he was permanent member of the German foundation "Alexander von-Humboldt"; Professor Sindona was member of the American Society of Mass Spectrometry from 1990. He was awarded of the "Piria Award for research"in 2008, and in 2011 he received the international award "Il Bergamotto" for his studies on the research activity linked to Calabria region.

Dr. Banoub is currently Head and Principal Senior Scientist, Special Projects Section at Fisheries and Ocean Canada (DFO), St. John's. He also holds two joint appointments as adjunct professor in Chemistry and Biochemistry Departments, Memorial University of Newfoundland. He has an active independent research program for over 40 years; during which, he supervised 34 graduate students and contributed to over 200 peer-reviewed publications.

He currently serves as Editor PLOS ONE and Vaccines journals. He is a member of the Editorial Boards of Rapid Communication in Mass Spectrometry, Journal of Chromatography B, Journal of Chromatography A, Food Chemistry, Journal of Analytical Sciences, and Methods and Instrumentations.

Dr. Banoub has a rich leadership experience. He served as a Manager of the Environmental Sciences Division (1997-2002) in DFO. He was also frequently appointed to senior executive positions in the Canadian government such as the International Science Strategy Committee which aimed at improving, funding science projects and developing national and international policies for various government departments and industry.

Dr. Banoub was the recipient of the "Dr. Albert R. Cox Research Award" (2002) from the Faculty of Medicine, Memorial University outstanding research on the isolation and structural identification of triterpine glycosides from quillaja saponoria molina and investigation of their adjuvant properties in a herpes simplex vaccine model. He has also received Fred P. Lossing Award for Distinguished contributions to mass spectrometry in Canada, 2012 and the Sir Winfield Templeman Award for Best Research in 2016for his work on Lignomics Analysis.

Maria Luisa Di Gioia (Ph.D., Calabria University) is a Researcher of Organic Chemistry at the Department of Pharmacy, Health and Nutritional Sciences of the University of Calabria. She holds the Italian qualification to Associate Professor in Organic Chemistry. Her research interests include the synthesis and characterization of molecules with potential biological activity. Peptides are an important part of her work.

作者簡介(中文翻譯)

喬凡尼·辛多納教授(Professor Giovanni Sindona)於2020年1月16日(星期四)去世,享年70歲,來自意大利卡拉布里亞大學化學系。我們失去了一位摯友、一位學者和一位紳士。喬凡尼於1949年4月9日出生於意大利梅西納,並於1972年在梅西納大學獲得化學榮譽學士學位。完成生物分析化學(質譜)的博士學位後,於1978年獲得著名的波恩大學物理化學研究所頒發的「亞歷山大·馮·洪堡基金會獎學金」。在80年代初,他作為北約學者在倫敦國王學院(King's College London)接受科林·B·瑞斯教授的指導,開發了核酸合成的新策略。

1990年,他成為卡拉布里亞大學的有機化學全職教授,並在馬格納·格雷西亞大學(University of Magna Graecia Catanzaro)教授有機化學。在他的學術生涯中,他擔任過重要的管理職位:1994年至1997年擔任數學、物理和自然科學學院院長,1997年至2003年及2007年至2015年擔任化學系主任,期間建立了前化學與化學技術系。

從1990年到2019年,辛多納教授組織並指導了五個針對年輕研究者的北約國際學校,專注於質譜在生物分子化學中的應用,這些學校在意大利及國外舉行。2009年,他成為多個北約-ASI、和平與安全科學計劃的共同主任,專注於生物劑和毒素的檢測,以防止國內安全中的生物恐怖主義。

辛多納教授是意大利化學學會(SCI)的成員,曾擔任質譜部門的主席及蛋白質組學跨部門小組的協調員;他還是SCI卡拉布里亞分會的主席,自1979年起成為德國「亞歷山大·馮·洪堡」基金會的永久成員;自1990年起,他是美國質譜學會的成員。他於2008年獲得「皮里亞研究獎」,並於2011年因其與卡拉布里亞地區相關的研究活動而獲得國際獎項「Il Bergamotto」。

班努布博士(Dr. Banoub)目前是加拿大漁業與海洋部(DFO)聖約翰特區特殊項目部的負責人及首席高級科學家。他還在紐芬蘭紀念大學的化學和生物化學系擔任兩個兼任教授職位。他擁有超過40年的獨立研究計劃;在此期間,他指導了34名研究生,並發表了超過200篇同行評審的論文。

他目前擔任《PLOS ONE》和《Vaccines》期刊的編輯,並是《質譜快速通訊》、《色譜學期刊B》、《色譜學期刊A》、《食品化學》、《分析科學期刊》和《方法與儀器》的編輯委員會成員。

班努布博士擁有豐富的領導經驗。他曾在DFO擔任環境科學部門經理(1997-2002)。他還經常被任命為加拿大政府的高級執行職位,例如國際科學戰略委員會,旨在改善資助科學項目並為各政府部門和行業制定國內和國際政策。

班努布博士於2002年獲得紀念大學醫學院的「阿爾伯特·R·考克斯研究獎」,以表彰他在從quillaja saponaria molina中分離和結構鑑定三萜苷及其在單純皰疹疫苗模型中的輔助特性研究方面的卓越研究。他還於2012年獲得弗雷德·P·洛辛獎,以表彰他對加拿大質譜學的傑出貢獻,並於2016年因其在木質分析方面的工作獲得溫菲爾德·坦普爾曼爵士最佳研究獎。

瑪麗亞·路易莎·迪·喬亞(Maria Luisa Di Gioia,博士,卡拉布里亞大學)是卡拉布里亞大學藥學、健康與營養科學系的有機化學研究員。她擁有意大利有機化學副教授的資格。她的研究興趣包括具有潛在生物活性的分子的合成和表徵,肽是她工作中的重要部分。