Computational Genomic Signatures (Synthesis Lectures on Biomedical Engineering)
Ozkan Ufuk Nalbantoglu, Khalid Sayood
- 出版商: Morgan & Claypool
- 出版日期: 2011-06-02
- 售價: $1,720
- 貴賓價: 9.5 折 $1,634
- 語言: 英文
- 頁數: 130
- 裝訂: Paperback
- ISBN: 1608451453
- ISBN-13: 9781608451456
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This text introduces the general concept of computational genomic signatures, and it reviews some of the DNA sequence models which can be used as computational genomic signatures. The text takes the position that a practical computational genomic signature consists of both a model and a measure for computing the distance or similarity between models. Therefore, a discussion of sequence similarity/distance measurement in the context of computational genomic signatures is presented. The remainder of the text covers various applications of computational genomic signatures in the areas of metagenomics, phylogenetics and the detection of horizontal gene transfer.
Table of Contents: Genome Signatures, Definition and Background / Other Computational Characterizations as Genome Signatures / Measuring Distance of Biological Sequences Using Genome Signatures / Applications: Phylogeny Construction / Applications: Metagenomics / Applications: Horizontal DNA Transfer Detection