Genome-Wide Association Studies: From Polymorphism to Personalized Medicine(Hardcover)
暫譯: 全基因組關聯研究:從多態性到個人化醫療(精裝版)

  • 出版商: Cambridge
  • 出版日期: 2016-01-14
  • 售價: $7,110
  • 貴賓價: 9.5$6,755
  • 語言: 英文
  • 頁數: 432
  • 裝訂: Hardcover
  • ISBN: 1107042763
  • ISBN-13: 9781107042766
  • 海外代購書籍(需單獨結帳)

商品描述

Over the last twenty years, genome-wide association studies (GWAS) have revealed a great deal about the genetic basis of a wide range of complex diseases and they will undoubtedly continue to have a broad impact as we move to an era of personalised medicine. This authoritative text, written by leaders and innovators from both academia and industry, covers the basic science as well as the clinical, biotechnological and pharmaceutical potential of these methods. With special emphasis given to highlighting pharmacogenomics and population genomics studies using next-generation technology approaches, this is the first book devoted to combining association studies with single nucleotide polymorphisms, copy number variants, haplotypes and expressed quantitative trait loci. A reliable guide for newcomers to the field as well as for experienced scientists, this is a unique resource for anyone interested in how the revolutionary power of genomics can be applied to solve problems in complex disease.

商品描述(中文翻譯)

在過去的二十年中,基因組廣泛關聯研究(GWAS)揭示了許多複雜疾病的遺傳基礎,並且隨著我們進入個人化醫療的時代,這些研究無疑將持續產生廣泛的影響。本書由來自學術界和產業界的領導者和創新者撰寫,涵蓋了這些方法的基礎科學以及臨床、生技和製藥潛力。特別強調使用下一代技術方法的藥物基因組學和人群基因組學研究,本書是第一本專門將關聯研究與單核苷酸多態性(single nucleotide polymorphisms)、拷貝數變異(copy number variants)、單倍型(haplotypes)和表達定量性狀位點(expressed quantitative trait loci)結合的書籍。這是一本可靠的指南,適合該領域的新手以及經驗豐富的科學家,對於任何有興趣了解基因組學的革命性力量如何應用於解決複雜疾病問題的人來說,這都是一個獨特的資源。