Nutrition and Epigenetics
暫譯: 營養與表觀遺傳學

《營養與表觀遺傳學》提供了有關飲食和營養因素在健康與疾病中調控基因表達的表觀遺傳控制的新資訊。每一章節都從不同的營養或飲食成分或成分群體的獨特視角出發，揭示了飲食因素調節表觀基因組並影響發展過程、慢性疾病和老化過程的新機制。這本關鍵的著作：

- 記錄了抗氧化劑的表觀遺傳效應及其健康益處
- 增進了對導致疾病易感性和健康老化機制的理解
- 說明了疾病的表觀遺傳起源發生在早期（胎兒）發展中
- 綜合了有關營養素與表觀基因組互動的數據

《營養與表觀遺傳學》強調了營養素、表觀遺傳學與健康之間的相互作用，為對營養、老化和代謝疾病感興趣的科學家和臨床研究者提供了重要資源。

Emily Ho is the endowed director of the Moore Family Center for Whole Grain Foods, Nutrition and Preventive Health. She is a full professor in the College of Public Health and Human Sciences, with an emphasis in nutrition, and is a principal investigator at the Linus Pauling Institute at Oregon State University. She joined the Oregon State University faculty in 2003 after receiving her Ph.D in human nutrition from the Ohio State University and completing her postdoctoral research at Children's Hospital Oakland Research Institute and UC Berkeley. During the course of her career, Dr. Ho has published 97 peer-reviewed articles and abstracts and four book chapters. She has been invited to give more than 40 presentations and has mentored more than 40 undergraduate and graduate students. She currently serves on the editorial board for Journal of Nutritional Biochemistry and Frontiers in Epigenomics. Her research interests are in the area of antioxidants and gene expression and dietary chemoprevention strategies. More specifically, she focuses on the effects of zinc status on DNA damage, DNA repair, and stress-response signal pathways. Another major focus in her laboratory is investigating the genetic and epigenetic mechanisms by which foods such as soy, tea, and cruciferous vegetables may protect against prostate cancer.

Frederick Domann is a professor of radiation oncology in the Free Radical and Radiation Biology Program at the University of Iowa. He is a distinguished alumnus from the University of Wisconsin where he earned his Ph.D in 1991 in human cancer biology under Kelly H. Clifton, studying radiation-induced thyroid and mammary carcinogenesis. He subsequently pursued postdoctoral research at the Arizona Cancer Center with G. Tim Bowden, where he studied the redox biology of gene expression. He joined the faculty at the University of Iowa in 1993 and has since become an internationally recognized expert in free radical biology, cancer metabolism, and epigenetics. His work has led to more than 140 peer-reviewed publications. Dr. Domann codirects the Free Radical Cancer Biology Program in the Holden Comprehensive Cancer Center at the University of Iowa. He serves on the Councils of the Society for Experimental Biology and Medicine and the Society for Free Radical Biology and Medicine. He is the recipient of the mentoring awards from the Radiation Research Society and the Graduate College of the University of Iowa. His research interests include transcriptional regulation, redox metabolism, and epigenetics of human diseases including cancer.

Emily Ho 是摩爾家族全穀食品、營養與預防健康中心的特聘主任。她是公共衛生與人類科學學院的全職教授，專注於營養領域，並且是俄勒岡州立大學林納斯·鮑林研究所的主要研究員。她於2003年加入俄勒岡州立大學的教職，之前在俄亥俄州立大學獲得人類營養學博士學位，並在奧克蘭兒童醫院研究所和加州大學伯克利分校完成博士後研究。在她的職業生涯中，Ho博士已發表97篇經過同行評審的文章和摘要，以及四個書章。她受邀進行超過40場演講，並指導了超過40名本科生和研究生。她目前擔任Journal of Nutritional Biochemistry和Frontiers in Epigenomics的編輯委員會成員。她的研究興趣集中在抗氧化劑、基因表達和飲食化學預防策略的領域。更具體地說，她專注於鋅狀態對DNA損傷、DNA修復和壓力反應信號通路的影響。她實驗室的另一個主要研究方向是探討大豆、茶和十字花科蔬菜等食物如何通過遺傳和表觀遺傳機制來保護前列腺癌。

Frederick Domann 是愛荷華大學自由基與輻射生物學計畫的放射腫瘤學教授。他是威斯康辛大學的傑出校友，於1991年在Kelly H. Clifton的指導下獲得人類癌症生物學博士學位，研究輻射引起的甲狀腺和乳腺癌發生。他隨後在亞利桑那癌症中心與G. Tim Bowden進行博士後研究，研究基因表達的氧化還原生物學。他於1993年加入愛荷華大學的教職，並成為國際公認的自由基生物學、癌症代謝和表觀遺傳學專家。他的研究成果已發表超過140篇經過同行評審的出版物。Domann博士共同指導愛荷華大學霍爾登綜合癌症中心的自由基癌症生物學計畫。他擔任實驗生物學與醫學學會和自由基生物學與醫學學會的理事會成員。他是輻射研究學會和愛荷華大學研究生學院的指導獎獲得者。他的研究興趣包括轉錄調控、氧化還原代謝以及人類疾病（包括癌症）的表觀遺傳學。