Antioxidants and Functional Foods for Neurodegenerative Disorders: Uses in Prevention and Therapy
暫譯: 抗氧化劑與功能性食品在神經退行性疾病中的應用:預防與治療

Kumar, Abhai, Bagchi, Debasis

  • 出版商: CRC
  • 出版日期: 2021-01-08
  • 售價: $7,740
  • 貴賓價: 9.5$7,353
  • 語言: 英文
  • 頁數: 454
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0367333228
  • ISBN-13: 9780367333225
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

Neurodegenerative diseases, including Alzheimer's and Parkinson's disease, are a growing problem across the world's aging population. Oxidative stress in the brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders.

This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants and inflammatory responses, and explores mitochondrial dysfunction. It then describes the protective abilities of antioxidants - including vitamin D, tocotrienol and coenzyme Q10 - against neurodegeneration. The book demonstrates the therapeutic potential of ketogenic diets, and highlights the roles of medicinal plants, phytopharmaceuticals, traditional medicines and food nutrients in neuroprotection.

Key Features:

  • Explains damage caused by numerous neurodegenerative disorders and the possible protection offered by antioxidants and functional foods.
  • Describes molecular mechanisms of neurodegeneration by oxidative stress, advancing age, diabetes and mitochondrial dysfunctions.
  • Demonstrates protection offered by nutraceuticals, antioxidants, botanical extracts and functional foods.

The book contains twenty-three chapters divided into six sections written by leading researchers. This book is essential reading for health professionals, dietitians, food and nutrition scientists and anyone wanting to improve their knowledge of etiology of neurodegenerative diseases.

商品描述(中文翻譯)

神經退行性疾病,包括阿茲海默症和帕金森病,正成為全球老年人口中日益嚴重的問題。大腦中的氧化壓力在這些疾病的共同病理生理中扮演著核心角色。本書介紹了抗氧化療法在預防和治療神經退行性疾病中的潛力的科學研究。

本書概述了氧化壓力和糖尿病在神經退行中的角色,描述了神經退行性疾病的分子機制,包括環境污染物和炎症反應的角色,並探討了線粒體功能障礙。接著,本書描述了抗氧化劑(包括維生素D、三烯生育醇和輔酶Q10)對抗神經退行的保護能力。本書展示了生酮飲食的治療潛力,並強調了藥用植物、植物藥、傳統醫藥和食品營養素在神經保護中的角色。

主要特點:
- 解釋了多種神經退行性疾病造成的損害以及抗氧化劑和功能性食品可能提供的保護。
- 描述了氧化壓力、年齡增長、糖尿病和線粒體功能障礙引起的神經退行的分子機制。
- 展示了營養補充品、抗氧化劑、植物提取物和功能性食品所提供的保護。

本書包含二十三章,分為六個部分,由領先的研究人員撰寫。本書是健康專業人員、營養師、食品和營養科學家以及任何希望提高對神經退行性疾病病因知識的人士的必讀書籍。

作者簡介

Abhai Kumar, Ph.D., received his Ph.D. degree in Biotechnology in 2008. Dr. Abhai is currently working as Research Scientist at DBT-BHU Interdisciplinary School of Life Sciences and Consultant Research Scientist at Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. Dr. Abhai served as Postdoctoral Fellow at University of Pittsburgh, Pittsburgh, USA from 2008 to 2010. Dr. Abhai identified several novel drug targets during his work at University of Pittsburgh, USA. He worked at India most prestigious institute National Institute of Immunology, New Delhi on glycoproteomics for drug targets of cancer . Dr. Abhai has published many research articles in journal of high impacts and wrote book chapter in various prestigious international books. He is reviewer of several journals and editorial board member. He is also working as ex-officio member of 'Chand Foundation' a voluntary organization dealing with mental health of elderly people in India. Dr. Abhai research interests include neurodegenerative disorders, free radicals, human diseases, anti-ageing and anti-inflammatory pathophysiology, and cognition.

Debasis Bagchi, PhD, MACN, CNS, MAIChE, received his Ph.D. in Medicinal Chemistry in 1982. Dr. Bagchi is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston, College of Pharmacy, Houston, TX, and the Chief Scientific Officer, R&D, Cepham Inc. Piscataway, NJ. He is also an Adjunct Faculty of the School of Pharmacy, Texas Southern University, Houston, TX. He served as the Senior Vice President of Research & Development of InterHealth Nutraceuticals Incorporated in Benicia, CA, from 1998 till Feb 2011. Dr. Bagchi received the Master of American College of Nutrition Award in early October 2010. He is currently the Chairman of International Society of Nutraceuticals and Functional Foods (ISNFF), Past President of American College of Nutrition, Clearwater, FL, and Past Chair of the Nutraceuticals and Functional Foods Division of Institute of Food Technologists (IFT), Chicago, IL. He is serving as a Distinguished Advisor on the Japanese Institute for Health Food Standards, Tokyo, Japan. Dr. Bagchi is a Member of the Study Section and Peer Review Committee of the National Institutes of Health (NIH), Bethesda, MD. Dr. Bagchi has 329 papers in peer reviewed journals, 33 books and numerous patents. He has delivered invited lectures in various national and international scientific conferences, organized workshops, and group discussion sessions. Dr. Bagchi is also a Member of the Society of Toxicology, Member of the New York Academy of Sciences, Fellow of the Nutrition Research Academy, and Member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, OH. Dr. Bagchi is the Associate Editors of the Journal of Functional Foods and the Journal of the American College of Nutrition, and also serving as Editorial Board Member of numerous peer reviewed journals, including Antioxidants & Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, The Original Internist, and others.

作者簡介(中文翻譯)

阿巴海·庫馬(Abhai Kumar),博士,於2008年獲得生物技術博士學位。阿巴海博士目前在印度瓦拉納西的班納拉斯印度大學醫學科學研究所神經學系擔任研究科學家,並在DBT-BHU跨學科生命科學學校擔任顧問研究科學家。阿巴海博士於2008年至2010年在美國匹茲堡大學擔任博士後研究員。在匹茲堡大學的工作中,阿巴海博士識別了幾個新型藥物靶點。他曾在印度最負盛名的機構——新德里的國家免疫學研究所,從事癌症藥物靶點的糖蛋白組學研究。阿巴海博士在高影響力期刊上發表了許多研究文章,並在各種國際知名書籍中撰寫了書章。他是多本期刊的審稿人和編輯委員會成員。此外,他還擔任印度「昌德基金會」(Chand Foundation)的名譽成員,該組織專注於老年人的心理健康。阿巴海博士的研究興趣包括神經退行性疾病、自由基、人類疾病、抗衰老和抗炎病理生理學以及認知。

德巴西斯·巴格奇(Debasis Bagchi),博士,MACN,CNS,MAIChE,於1982年獲得藥物化學博士學位。巴格奇博士是德克薩斯州休斯頓大學藥學院藥理學與藥學科的教授,並擔任Cepham Inc.(新澤西州皮斯卡塔維)的首席科學官。他同時也是德克薩斯南方大學藥學院的兼任教員。巴格奇博士於1998年至2011年2月擔任InterHealth Nutraceuticals Incorporated(加州貝尼西亞)的研究與開發高級副總裁。巴格奇博士於2010年10月初獲得美國營養學院大獎。他目前是國際營養補充品與功能性食品學會(ISNFF)的主席,曾任美國營養學院(佛羅里達州克利爾沃特)會長,以及食品技術學會(IFT,伊利諾伊州芝加哥)營養補充品與功能性食品部門的前主席。他還擔任日本健康食品標準研究所的特聘顧問(東京,日本)。巴格奇博士是美國國立衛生研究院(NIH,馬里蘭州貝塞斯達)研究小組和同行評審委員會的成員。巴格奇博士在同行評審期刊上發表了329篇論文,出版了33本書籍及多項專利。他在各種國內外科學會議上發表了受邀演講,組織了工作坊和小組討論會。巴格奇博士還是毒理學會的成員,紐約科學院的成員,營養研究學院的院士,以及俄亥俄州萊特·帕特森空軍基地TCE利益相關者委員會的成員。巴格奇博士是《功能性食品期刊》和《美國營養學院期刊》的副編輯,並擔任多本同行評審期刊的編輯委員會成員,包括《抗氧化劑與還原信號》、《癌症快報》、《毒理學機制與方法》、《原始內科醫生》等。