Gene Environment Interactions: Nature and Nurture in the Twenty-First Century
暫譯: 基因與環境互動:二十一世紀的自然與培育
Smith, Moyra
- 出版商: Academic Press
- 出版日期: 2020-01-14
- 售價: $5,130
- 貴賓價: 9.5 折 $4,874
- 語言: 英文
- 頁數: 438
- 裝訂: Quality Paper - also called trade paper
- ISBN: 0128196130
- ISBN-13: 9780128196137
海外代購書籍(需單獨結帳)
商品描述
Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters, Dr. Smith discusses interactions with the environment, human adaptations to environmental stimuli, pathogen encounters across the centuries, epigenetic modulation of gene expression, transgenerational inheritance, the microbiome's intrinsic effects on human health, and the gene-environment etiology of cardiovascular, metabolic, psychiatric, behavioral and monogenic disorders.
Later chapters illuminate how our new understanding of gene environment interactions are driving advances in precision medicine and novel treatments. In addition, the book's author shares strategies to support clinical translation of these scientific findings to improve heath literacy among the general population.
- Offers a thorough, interdisciplinary discussion on recent revelations from gene environment interaction studies
- Illuminates environmental factors affecting disease-gene etiology and treatment
- Supports the clinical translation of gene environment interaction findings into novel therapeutics and precision medicine
商品描述(中文翻譯)
《基因與環境互動:二十一世紀的自然與培育》提供了一個罕見的協同視角,探討基因與環境互動研究中的持續揭示,結合了表觀遺傳學、微生物組學、疾病病因學和毒理學的關鍵主題,以闡明臨床轉化的途徑及向精準醫療的範式轉變。在十一章中,史密斯博士討論了與環境的互動、人類對環境刺激的適應、世紀以來的病原體接觸、基因表達的表觀遺傳調控、跨代遺傳、微生物組對人類健康的內在影響,以及心血管、代謝、精神、行為和單基因疾病的基因-環境病因學。
後面的章節闡明了我們對基因與環境互動的新理解如何推動精準醫療和新療法的進展。此外,書中的作者分享了支持這些科學發現臨床轉化的策略,以提高一般人群的健康素養。
- 提供對基因與環境互動研究中最近揭示的徹底跨學科討論
- 闡明影響疾病-基因病因學和治療的環境因素
- 支持將基因與環境互動的發現轉化為新療法和精準醫療的臨床應用