Modeling and Control of Infectious Diseases in the Host: With MATLAB and R
暫譯: 宿主中傳染病的建模與控制：使用 MATLAB 和 R
Hernandez-Vargas, Esteban A.
- 出版商: Academic Press
- 出版日期: 2019-02-19
- 售價: $4,440
- 貴賓價: 9.5 折 $4,218
- 語言: 英文
- 頁數: 256
- 裝訂: Quality Paper - also called trade paper
- ISBN: 0128130520
- ISBN-13: 9780128130520
-
相關分類:
Matlab
海外代購書籍(需單獨結帳)
商品描述
Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R.
- Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases
- Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases
- Presents a theoretic approach to schedule drug treatments
商品描述(中文翻譯)
《宿主內傳染病的建模與控制：使用 MATLAB 和 R》提供了對健康與疾病的整體理解，通過呈現影響藥物開發的定量決策主題。本書介紹了不同病毒感染的建模進展，詳細剖析了關鍵參與者的貢獻及其相互作用。通過結合量身定制的體內實驗和數學建模方法，本書闡明了在最致命的病毒感染宿主中，不同潛在機制的相對貢獻，包括 HIV、流感和埃博拉。使用 MATLAB 和 R 解釋了參數擬合、建模和控制應用的示例。
- 提供了一個多尺度框架，將宿主內感染動力學（個體層面）與宿主間傳播適應度（流行病學層面）聯繫起來，適用於病毒傳染病
- 包含藥物動力學/藥效學（PK/PD）建模和模擬方法，以提高臨床前開發階段的效率和決策能力
- 提出了一種理論方法來安排藥物治療時間表
