Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer's Disease
暫譯: 神經退行性疾病治療的藥物發現方法:阿茲海默症

  • 出版商: Academic Press
  • 出版日期: 2016-09-30
  • 售價: $5,470
  • 貴賓價: 9.5$5,197
  • 語言: 英文
  • 頁數: 316
  • 裝訂: Hardcover
  • ISBN: 0128028106
  • ISBN-13: 9780128028100
  • 海外代購書籍(需單獨結帳)

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商品描述

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success.

The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders.

  • Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders
  • Examines different classes of compounds currently being used in discovery and development stages
  • Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions
  • Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource

商品描述(中文翻譯)

《神經退行性疾病治療的藥物發現方法:阿茲海默症》探討了神經退行性疾病的藥物發現過程,特別聚焦於阿茲海默症,並闡述了確保未來研究和治療成功所需的範式。

本書探討了診斷、流行病學、藥物發現策略、當前療法等多個方面,提供了一個全面的方法來發現、開發和治療阿茲海默症。通過涵蓋針對性藥物設計、臨床前研究以及小鼠和大鼠模型的最新研究,本書是所有在此領域工作的藥物科學家、藥理學家、神經科學家和臨床研究人員必備的資源。它說明了為什麼這些藥物在臨床階段往往失敗,並在改善其他神經退行性疾病治療的藥物發現過程的整體背景下檢視阿茲海默症。

- 提供了在神經退行性疾病治療的藥物發現中所需的化學考量的彙編
- 檢視目前在發現和開發階段使用的不同類別的化合物
- 探討了體外和體內模型在將這些模型轉化為人類條件方面的能力
- 提煉了阿茲海默症研究多個領域中最重要的信息,以提供一個單一、全面且平衡的資源