The Endocannabinoid System in Local and Systemic Inflammation (Colloquium Series on Integrated Systems Physiology: from Molecule to Function)
暫譯: 局部與全身性發炎中的內源性大麻素系統(綜合系統生理學系列:從分子到功能)
Melanie E. M. Kelly, Christian Lehmann, Juan Zhou
- 出版商: Morgan & Claypool
- 出版日期: 2017-03-29
- 售價: $2,730
- 貴賓價: 9.5 折 $2,594
- 語言: 英文
- 頁數: 208
- 裝訂: Paperback
- ISBN: 1615047484
- ISBN-13: 9781615047482
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商品描述
This book focuses on the role of the endocannabinoid system in local and systemic inflammation, with individual chapters written by experts in the field of cannabinoid research and medicine. The topics explore the actions of the endocannabinoid system on the immune system, including neuroinflammation in autoimmune disorders such as multiple sclerosis, and in neurodegenerative disorders such as Huntington's and Alzheimer's, as well as local and systemic inflammatory conditions affecting organs including the eye (uveitis and corneal inflammation), the bladder (interstitial cystitis), pancreas (diabetes), cardiovascular system (stroke), joints (arthritis), and sepsis. The objective of this book is to provide knowledge transfer on the use of cannabinoids in inflammatory disease by critically examining preclinical and clinical research on the immunomodulatory actions of the endocannabinoid system, with specific emphasis on the actions of cannabinoids in diseases where inflammation is a prominent component. By drawing these results together, we seek to provide further understanding of the complexities of endocannabinoid system modulation of immune function and identify potential uses and limitations for cannabinoid-based therapeutics.
商品描述(中文翻譯)
本書專注於內源性大麻素系統在局部和全身性炎症中的角色,各章節由大麻素研究和醫學領域的專家撰寫。主題探討內源性大麻素系統對免疫系統的作用,包括在自體免疫疾病(如多發性硬化症)中的神經炎症,以及在神經退行性疾病(如亨廷頓病和阿茲海默症)中的影響,還有影響器官的局部和全身性炎症狀況,包括眼睛(葡萄膜炎和角膜炎)、膀胱(間質性膀胱炎)、胰臟(糖尿病)、心血管系統(中風)、關節(關節炎)和敗血症。本書的目標是通過批判性地檢視內源性大麻素系統的免疫調節作用的臨床前和臨床研究,提供有關大麻素在炎症性疾病中使用的知識轉移,特別強調大麻素在炎症為主要成分的疾病中的作用。通過整合這些結果,我們希望進一步理解內源性大麻素系統調節免疫功能的複雜性,並識別基於大麻素的治療的潛在用途和限制。