Cytokine and Chemokine Networks in Cancer
暫譯: 癌症中的細胞激素與趨化因子網絡
Mir, Manzoor Ahmad
- 出版商: Springer
- 出版日期: 2024-10-20
- 售價: $7,790
- 貴賓價: 9.5 折 $7,401
- 語言: 英文
- 頁數: 440
- 裝訂: Quality Paper - also called trade paper
- ISBN: 981994659X
- ISBN-13: 9789819946594
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商品描述
Cytokine and Chemokine Networks in Cancer" provides a comprehensive exploration of the roles of cytokines and chemokines in cancer biology. It offers valuable insights into their diagnostic, prognostic, and therapeutic implications, making it a valuable resource for researchers, clinicians, and students interested in the field of cancer immunology and therapy. This book illustrates the importance and significance of the cytokine and chemokine signaling networks in tumor development and progression. It describes the complex networks mediated by cytokine and chemokine receptors promoting tumor cell proliferation, site-directed metastasis, and activation of angiogenic switch in tumor cells. The books also shed light on the heterogeneity of cytokines and chemokine in solid malignancies and their impact on tumor progression and therapeutic outcomes. The chapters provide current information about the types of cytokine-chemokine interactions in promoting cancer stem cell-like characteristics, epithelial to mesenchymal transition, and modulation of the tumor microenvironment. The significance of the complex interactions in cancer biology in the light of therapeutic resistance is also highlighted. The chapters also describe recent advancements in the therapeutic potential of targeting the pro-tumor cytokine and chemokine networks and limiting tumor cell metastasis. Finally, the book also provides a comprehensive yet representative description of a large number of challenges associated with targeting these vital chemokine-cytokine networks. Given its content, the book provides valuable information for researchers in the field of cancer biology and molecular medicine.
商品描述(中文翻譯)
《細胞激素與趨化因子在癌症中的網絡》提供了對細胞激素和趨化因子在癌症生物學中角色的全面探索。它對於這些因子的診斷、預後和治療意義提供了寶貴的見解，使其成為對癌症免疫學和治療領域感興趣的研究人員、臨床醫生和學生的重要資源。本書闡述了細胞激素和趨化因子信號網絡在腫瘤發展和進展中的重要性和意義。它描述了由細胞激素和趨化因子受體介導的複雜網絡，促進腫瘤細胞增殖、定向轉移以及腫瘤細胞中的血管生成開關的激活。本書還揭示了固體惡性腫瘤中細胞激素和趨化因子的異質性及其對腫瘤進展和治療結果的影響。各章節提供了有關促進癌症幹細胞樣特徵、上皮到間質轉變以及腫瘤微環境調節的細胞激素-趨化因子相互作用類型的最新信息。還強調了在治療抵抗的背景下，癌症生物學中複雜相互作用的重要性。各章節還描述了針對促腫瘤細胞激素和趨化因子網絡的治療潛力的最新進展，以及限制腫瘤細胞轉移的策略。最後，本書還提供了針對這些重要的趨化因子-細胞激素網絡所面臨的眾多挑戰的全面而具代表性的描述。鑑於其內容，本書為癌症生物學和分子醫學領域的研究人員提供了寶貴的信息。
作者簡介
Dr. Manzoor Ahmad Mir holds Master's Degree in Zoology with Gold Medal from HNBG Central University and after qualifying prestigious National level CSIR-JRF-NET examination; got his Ph. D from Jawaharlal Nehru University New Delhi and CSIR-Institute of Microbial Technology Chandigarh in the field of Immunopathology. His research interest is Cancer Biology with specialization in Drug repurposing and combination therapy of breast cancer and to elucidate the molecular mechanism behind it, besides use of natural agents in treating cancer. He is also working on expression pattern and prognostic significance of chemokines/cytokines of CDKs in breast cancer besides virtual screening of drugs for cancer treatment and their mechanistic elucidation. He has published more than 50 high-impact research papers and book chapters, in recognition of which he has received several awards and Royalties from international publishing houses. Dr. Manzoor has authored more than 16 books with internationalpublishers like Elsevier USA and Nova Science Publisher USA, Bentham Sciences, IGI Global, Springer-Nature to name a few. He is on the editorial board and Reviewer of some prestigious journals and has been an invited speaker at various scientific meetings/conferences within India and abroad. He is member of many scientific organizations and societies like American Association of Cancer Research, Fellow of Royal British Society, American Association of Clinical Oncology, International Immunology Association, etc. Dr Manzoor was awarded Teachers Associate Research Excellence Fellowship (TARE) by DST Govt of India and Summer Research Fellowship Programme (SRFP-2019) by Indian Academy of Sciences and National Science Academy. Dr Manzoor has developed Massive Open Online Course (MOOCs) in Immunology, Human Genetics and Endocrinology for UG students sanctioned by UGC-Consortium for Educational Communication (CEC) SWAYAM Ministry of HRD Govt of India. He has research and teaching experience of 15 years in Cancer Biology, Animal cell and Tissue Technology, Molecular Modelling and Drug Design, Comparative Immunology. He currently teaches Cancer Biology, and Immunology at the Department of Bioresources, School of Biological Sciences, University of Kashmir. He is presently heading the Department of Bioresources, University of Kashmir.
作者簡介(中文翻譯)
馬祖爾·艾哈邁德·米爾博士擁有HNBG中央大學的動物學碩士學位，並以金獎畢業。在通過國家級的CSIR-JRF-NET考試後，他在新德里的賈瓦哈拉爾·尼赫魯大學和昌迪加爾的CSIR微生物技術研究所獲得免疫病理學的博士學位。他的研究興趣是癌症生物學，專注於乳腺癌的藥物重定位和聯合療法，並闡明其背後的分子機制，此外還研究使用天然藥物治療癌症。他還在研究乳腺癌中CDKs的化學因子/細胞因子的表達模式及其預後意義，並進行癌症治療藥物的虛擬篩選及其機制的闡明。他已發表超過50篇高影響力的研究論文和書籍章節，因而獲得了多項獎項和國際出版商的版稅。馬祖爾博士與國際出版商如美國Elsevier、Nova Science Publisher、美國Bentham Sciences、IGI Global、Springer-Nature等合作，撰寫了超過16本書籍。他是一些知名期刊的編輯委員會成員和審稿人，並曾在印度及國外的各種科學會議/研討會上擔任受邀演講者。他是許多科學組織和學會的成員，如美國癌症研究協會、英國皇家學會院士、美國臨床腫瘤學會、國際免疫學協會等。馬祖爾博士曾獲得印度政府DST頒發的教師助理研究卓越獎學金（TARE）和印度科學院及國家科學院的夏季研究獎學金計劃（SRFP-2019）。他為UG學生開發了免疫學、人類遺傳學和內分泌學的慕課（MOOCs），該課程經UGC教育傳播聯盟（CEC）SWAYAM印度人力資源部批准。他在癌症生物學、動物細胞和組織技術、分子建模和藥物設計、比較免疫學方面擁有15年的研究和教學經驗。目前，他在喀什米爾大學生物資源系教授癌症生物學和免疫學，並擔任該系主任。
