Multifunctional and Targeted Theranostic Nanomedicines: Formulation, Design and Applications
Jain, Keerti, Jain, N. K.
- 出版商: Springer
- 出版日期: 2024-08-25
- 售價: $6,970
- 貴賓價: 9.5 折 $6,622
- 語言: 英文
- 頁數: 417
- 裝訂: Quality Paper - also called trade paper
- ISBN: 9819905400
- ISBN-13: 9789819905409
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商品描述
This book discusses approaches based on multifunctional and targeted theranostic nanomedicines for improving diagnosis and drug delivery. It explores nanomedicines based on nanocarriers like liposomes, ethosomes, niosomes, polymeric nanoparticles, lipidic nanoparticles, metallic nanoparticles, micelles, dendrimers, quantum dots, carbon-based nanomaterials including carbon nanotubes, carbon dots, carbon quantum dots, graphene oxide, and fullerene. This book reviews designing, conjugation, optimization, formulation and development, and scale-up of multifunctional and targeted theranostic nanomedicines. It examines major challenges in developing nanomaterials that can be applied to nanomedicine with high biocompatibility and biodegradability for diagnostic and therapeutic purposes. Lastly, it addresses the most promising approaches at both commercialization and regulatory steps for bringing theranostic nanomedicine from research laboratories to clinics for patient use.
商品描述(中文翻譯)
本書討論了基於多功能和靶向治療診斷(theranostic)奈米藥物的各種方法,以改善診斷和藥物傳遞。它探討了基於奈米載體的奈米藥物,如脂質體(liposomes)、乙醇脂質體(ethosomes)、非離子脂質體(niosomes)、聚合物奈米顆粒(polymeric nanoparticles)、脂質奈米顆粒(lipidic nanoparticles)、金屬奈米顆粒(metallic nanoparticles)、微胞(micelles)、樹狀聚合物(dendrimers)、量子點(quantum dots)、碳基奈米材料(包括碳納米管、碳點、碳量子點、氧化石墨烯和富勒烯)。本書回顧了多功能和靶向治療診斷奈米藥物的設計、結合、優化、配方開發及放大生產。它檢視了開發可應用於奈米醫學的奈米材料所面臨的主要挑戰,這些材料需具備高生物相容性和生物降解性,以用於診斷和治療目的。最後,本書探討了將治療診斷奈米藥物從研究實驗室推向臨床應用的最有前景的方法,包括商業化和監管步驟。
作者簡介
Dr. Keerti Jain, Assistant Professor, Department of Pharmaceutics, at National Institute of Pharmaceutical Education and Research (NIPER) - Raebareli, India, earned her M. Pharm. and Doctorate from the Department of Pharmaceutical Sciences, Dr. H. S. Gour Central University, Sagar. She did her Post Doctorate from M. S. University of Vadodara, India, as SERB-National Post-Doctoral Fellow. She has more than 12 years of research experience on Nanomedicine based drug delivery systems and supervised M. Pharm., M.S. Pharm., Pharm.D. and Ph.D. students for their research work. She is the author of more than 70 international publications in peer reviewed-high impact factor journals.
Dr. Jain has filed five patents from her innovative research and received funding for research projects from ICMR and SERB, New Delhi. She has been awarded for her research work with prestigious ICMR - Shakuntala Amir Chand Award, Most Innovative Idea Award, SPER-WF Young Scientist Award 2022, SERB - NPDF, Fellowship for the training of young scientist (MPCST), Travel grant award (INSA), and International Travel Fellowship (ICMR and DBT). She has been enlisted among World's Top 2% Scientists consecutively for three years from 2020 to 2022 in the list created by Stanford University, USA.
Prof. N. K. Jain is an internationally renowned academician and researcher. He has worked as Professor and Principal, College of Pharmacy, Nasik; Professor and Head, Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar; Principal, College of Pharmacy, New Delhi; Visiting Professor, Dubai Pharmacy College, Dubai (UAE); and Head, Pharmacy Department, Delhi University. After his superannuation, Prof. Jain was a Director, ISF College of Pharmacy, Moga, Punjab, India) as Emeritus Fellow (U.G.C.) at Rajiv Gandhi Technological University, Bhopal, M.P., India. He has published more than 480 research articles in journals of high repute. He has beena reviewer for several international and national research journals. He is the recipient of several awards, notably, IDMA Research Award in Industrial Pharmacy Dr. (Mrs.) ManjuSree Pal Memorial Award of the Association of Pharmaceutical Teachers of India for Best Pharmaceutical Scientist, and Schroff Memorial National Award for his outstanding contributions as an author, academician, and scientist by the Indian Hospital Pharmacists' Association, and was elected for the prestigious and Indian Association of Pharmaceutical Scientists and Technologists (IAPST) Lifetime Achievement Award conferred at the 5th IAPST Annual Convention. Most recently he was conferred the prestigious "APTI Shri Bhojraj Panjamool Lifetime Achievement Award" at 25th APTICON, JSS Mysore, India by the Association of Pharmaceutical Teachers of India on 2nd Sept 22.
According to a recent ranking announced by the Stanford University Scientists [based on a database of over 1 lakh top scientists ofthe world on the basis of standardized citation indicators], Prof. N.K. Jain is included in top 2% scientists in the world in the area of Pharmacology and Pharmacy, consecutively for 3 years.
作者簡介(中文翻譯)
Dr. Keerti Jain是印度國立藥學教育與研究院(NIPER)- Raebareli藥劑學系的助理教授,她在Dr. H. S. Gour中央大學(Sagar)的藥學科學系獲得碩士和博士學位。她在印度瓦多達拉的M. S. 大學完成了博士後研究,並擔任SERB國家博士後研究員。她在納米醫學基礎的藥物傳遞系統方面擁有超過12年的研究經驗,並指導碩士、碩士藥學、藥學博士及博士生的研究工作。她在同行評審的高影響因子期刊上發表了超過70篇國際論文。
Jain博士已經為她的創新研究申請了五項專利,並獲得了來自ICMR和新德里的SERB的研究項目資助。她因其研究工作獲得了多項榮譽,包括ICMR - Shakuntala Amir Chand獎、最具創新理念獎、SPER-WF年輕科學家獎2022、SERB - NPDF、年輕科學家培訓獎學金(MPCST)、旅行補助獎(INSA)以及國際旅行獎學金(ICMR和DBT)。她在2020年至2022年間連續三年被斯坦福大學列入全球前2%科學家名單。
N. K. Jain教授是一位國際知名的學者和研究者。他曾擔任納西克藥學院的教授及院長、Dr. H. S. Gour大學藥學科學系的教授及系主任、新德里藥學院的院長、迪拜藥學院的客座教授(阿聯酋)以及德里大學藥學系的系主任。退休後,Jain教授擔任印度旁遮普省Moga的ISF藥學院院長,並在印度博帕爾的拉吉夫甘地技術大學擔任榮譽研究員(U.G.C.)。他在高聲望的期刊上發表了超過480篇研究文章,並擔任多個國際和國內研究期刊的審稿人。他獲得了多項獎項,特別是工業藥學的IDMA研究獎、印度藥學教師協會頒發的最佳藥學科學家Dr. (Mrs.) ManjuSree Pal紀念獎,以及印度醫院藥劑師協會頒發的Schroff紀念國家獎,以表彰他作為作者、學者和科學家的卓越貢獻,並被選為印度藥學科學家與技術人員協會(IAPST)頒發的終身成就獎的獲得者,該獎項在第五屆IAPST年會上頒發。最近,他於2022年9月2日在印度邁索爾的第25屆APTICON上獲得了印度藥學教師協會頒發的“APTI Shri Bhojraj Panjamool終身成就獎”。
根據斯坦福大學科學家最近公布的排名(基於超過10萬名世界頂尖科學家的標準化引用指標數據庫),N. K. Jain教授在藥理學和藥學領域連續三年被列入全球前2%科學家。