Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives
暫譯: 樹狀聚合物在奈米醫學中的應用：概念、理論與法規觀點
Mehra, Neelesh Kumar, Jain, Keerti
- 出版商: CRC
- 出版日期: 2021-03-23
- 售價: $8,100
- 貴賓價: 9.5 折 $7,695
- 語言: 英文
- 頁數: 314
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 0367466058
- ISBN-13: 9780367466053
海外代購書籍(需單獨結帳)
商品描述
Dendrimers, hyperbranched macromolecules, emerged just few decades ago but show promising potential as drug delivery nanocarriers, theranostic agents and gene vectors; in the pharmaceutical research and innovation area as well as in other healthcare applications. Although tremendous advancements have been made in dendrimer chemistry and their applications since their emergence, the synthesis, development and design of pure and safe dendrimer-based products have been a major challenge in this area.
This book, edited by well-known researchers in the area of nanomaterials and drug-based drug delivery applications, exhaustively covers the nanotechnological aspects, concepts, properties, characterisation, application, biofate and regulatory aspects of dendrimers. It includes sixteen vivid chapters by renowned formulators, researchers and academicians from all over the world, highlighting their specialised areas of interest in the fields of chemistry, biology, pharmacy and nanomedicine.
Features:
- Highlights dendrimers' advancements in nanomedicine in the development of safe healthcare and biotechnological products
- Covers physicochemical aspects, biofate, drug delivery aspects and gene therapy using dendrimers
- Covers biomedical application of dendrimers in the field of biological sciences
- Gives examples of dendrimer-guest interaction chemistry
Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives provides the comprehensive overview of the latest research efforts in designing, optimising, development and scale-up of dendrimer-mediated delivery systems. It analyses the key challenges of synthesis, design, molecular modelling, fundamental concepts, drug delivery aspects, analytical tools and biological fate as well as regulatory consideration to the practical use of dendrimer application.
Dr. Neelesh Kumar Mehra Assistant Professor of Pharmaceutics in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He has authored more than sixty peer-reviewed publications in highly reputed international journals, as well as book chapters and contributions on two patents. Dr. Mehra has 11 years of rich research and teaching experience in the formulation and development of complex, innovative biopharmaceutical products including micro- and nanotechnologies for regulated markets.
Dr. Keerti Jain Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, NIPER, Raebareli, India. For more than 10 years, she has been actively engaged in formulation and development of nanomedicines. Dr. Jain has supervised masters and doctoral pharmaceutics students in their research works which have been published in high quality, good impact factor journals. She has also authored more than 60 international manuscripts in peer reviewed high impact journals. In 2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.
商品描述(中文翻譯)
樹狀聚合物（Dendrimers），一種超支化大分子，僅在幾十年前出現，但在藥物傳遞奈米載體、治療診斷劑和基因載體方面顯示出良好的潛力；在製藥研究與創新領域以及其他醫療應用中。儘管自其出現以來，樹狀聚合物化學及其應用已取得了巨大的進展，但純淨且安全的樹狀聚合物產品的合成、開發和設計仍然是該領域的一大挑戰。
本書由奈米材料和基於藥物的藥物傳遞應用領域的知名研究者編輯，全面涵蓋了樹狀聚合物的奈米技術方面、概念、特性、表徵、應用、生物命運及監管方面。書中包含來自全球各地的知名配方師、研究者和學者撰寫的十六個生動章節，突顯他們在化學、生物學、藥學和奈米醫學領域的專業興趣。
特色：
- 突出樹狀聚合物在奈米醫學中在安全醫療和生物技術產品開發方面的進展
- 涵蓋樹狀聚合物的物理化學特性、生物命運、藥物傳遞方面及基因治療
- 涵蓋樹狀聚合物在生物科學領域的生物醫學應用
- 提供樹狀聚合物-客體相互作用化學的例子
《樹狀聚合物在奈米醫學中的應用：概念、理論與監管視角》提供了最新研究努力的全面概述，涵蓋樹狀聚合物介導的傳遞系統的設計、優化、開發和擴大。它分析了合成、設計、分子建模、基本概念、藥物傳遞方面、分析工具和生物命運的關鍵挑戰，以及樹狀聚合物應用的實際使用中的監管考量。
Dr. Neelesh Kumar Mehra 是印度海得拉巴國家藥物教育與研究所（NIPER）藥劑學系的助理教授。他在高度知名的國際期刊上發表了超過六十篇的同行評審出版物，並撰寫了書章及兩項專利的貢獻。Mehra博士在複雜、創新生物製藥產品的配方和開發方面擁有11年的豐富研究和教學經驗，包括針對受監管市場的微型和奈米技術。
Dr. Keerti Jain 是印度Raebareli的NIPER藥劑學系助理教授。她在奈米醫藥的配方和開發方面活躍了超過10年。Jain博士指導了碩士和博士藥劑學學生的研究工作，這些研究已在高品質、高影響因子的期刊上發表。她還在同行評審的高影響期刊上發表了超過60篇國際手稿。2019年，她獲得了享有盛譽的ICMR-Amir Shakuntala獎。
作者簡介
Dr. Neelesh Kumar Mehra is working as Assistant Professor of Pharmaceutics, at Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He earned his PhD with Prof. N.K. Jain from Dr. H.S. Gour University, Sagar and PostDoc from Texas A & M Health Science Centre, Kingsville, TX, USA. He served as Manager in Product Development, Sentiss Pharma Pvt Ltd. Gurgaon for development, scale-up and technology transfer of complex ophthalmic, inhalation, and otic pharmaceutical products. He received "TEAM AWARD" for successfully commercialization of Ophthalmic Suspension product. He is as an Editorial member of "Drug Delivery Letters" Journal, Bentham sciences. He has authored more than 50 peer-reviewed publications in high repute International Journals, 07 book chapters contributions. He guided PhD and M.S. students for their dissertations/research projects. He has received numerous outstanding awards including Young Scientist, Team Awards for their research output. He is peer reviewer of various international Journals and publishers. Currently he is editing books on Biopharmaceutical and nanotechnology based with CRC Press and Elsevier Pvt Ltd. He has 11 years rich research and teaching experience in the formulation and development of complex, innovative ophthalmic and injectable biopharmaceutical products including micro- and nano-technologies for regulated market and so on.
Dr. Keerti Jain earned her M. Pharm. and doctorate degree from Dr. H. S. Gour Central University, Sagar. She did her Post Doctorate from M. S. University of Vadodara, India as SERB-National Post-Doctoral Fellow. She has more 10 years of research experienced on Nanomedicine based drug delivery systems. Currently, she is efficiently fulfilling her responsibilities as Asst. Prof. and Scientists at Department of Pharmaceutics, NIPER, Rae Bareli, Lucknow, UP INDIA. Dr. Jain has supervised M. Pharm. and Pharm. D. students for their research works which have been published in quality journals with good impact factor. She is author of more than 60 international manuscripts in peer reviewed-high impact journals, including publications in Progress in Polymer Science having impact factor: 26.932, in biomaterials, drug discovery today, nanomedicine Current Opinion in Pharmacology, Antimicrobial agents and chemotherapy and other high impact factors. Her review articles entitled "Dendrimer Toxicity: Let's Meet the Challenge" and "Dendrimers as Nanocarriers in Drug Delivery" published in International Journal of Pharmaceutics (2010) and Progress in Polymer Science (2014) was listed in top 25 articles. She has been author of 10 books and book chapters with international publishers. She has been awarded with research fellowships including SERB - Post Doctorate Fellowship, Senior research fellowship (CSIR), Junior research fellowship (UGC), Fellowship for training of young scientist (MPCST), Travel grant award (INSA) and International Travel Fellowship (ICMR and DBT) apart from several other prestigious grants, fellowships and awards. She has been nominated for Ranbaxy Research Scholar Award - 2012 and BioAsia Innovation Award - 2015. She has also been awarded with many best research presentation award in international conferences like NIPiCON-2014, International Science Congress-2012, APTI - Jaipur - 2018, SPER-Bangkok - 2019 and so on. She has been recipient of Pharmaceutical Science Alumni Award-2006 at Dr. H. S. Gour University, Sagar (M.P.). Till date she has been invited to present her research work at several national and seven international conferences including ICYRAM-2012 held at Singapore, Bioencapsulation - 2016 held at Lisbon, Portugal and International Conference - 2019 held at Bangkok. She won most innovative Idea award in LUFTHANSA impact week, which is a Reputed international platform.
作者簡介(中文翻譯)
尼勒什·庫馬爾·梅赫拉博士目前擔任印度海得拉巴國立藥學教育與研究所（NIPER）藥劑學系的助理教授。他在德拉H.S. Gour大學（Sagar）獲得了N.K. Jain教授的博士學位，並在美國德克薩斯州金斯維爾的德州A&M健康科學中心完成了博士後研究。他曾在Sentiss Pharma Pvt Ltd.的產品開發部門擔任經理，負責複雜的眼科、吸入和耳用藥品的開發、放大和技術轉移。他因成功商業化眼科懸浮液產品而獲得了團隊獎。他是藥物傳遞快報期刊的編輯成員，該期刊由Bentham Sciences出版。他在高聲望的國際期刊上發表了超過50篇同行評審的論文，並貢獻了7章書籍。他指導了博士和碩士學生的論文/研究項目。他獲得了多項卓越獎項，包括青年科學家獎和研究成果團隊獎。他是多個國際期刊和出版商的同行評審人。目前，他正在與CRC Press和Elsevier Pvt Ltd編輯有關生物製藥和納米技術的書籍。他在複雜、創新眼科和注射生物製藥產品的配方和開發方面擁有11年的豐富研究和教學經驗，包括針對受管制市場的微型和納米技術等。
基爾提·賈因博士在德拉H.S. Gour中央大學（Sagar）獲得了藥學碩士和博士學位。她在印度瓦多達拉的M.S.大學完成了博士後研究，並獲得了SERB國家博士後獎學金。她在基於納米醫學的藥物傳遞系統方面擁有超過10年的研究經驗。目前，她在印度烏塔爾普拉德什州的NIPER（Rae Bareli）藥劑學系擔任助理教授和科學家，並高效地履行她的職責。賈因博士指導了藥學碩士和藥學博士學生的研究工作，這些研究成果已在高影響因子的優質期刊上發表。她在同行評審的高影響期刊上發表了超過60篇國際手稿，包括在聚合物科學進展上發表的影響因子為26.932的文章，以及在生物材料、藥物發現今日、納米醫學、藥理學當前意見、抗微生物劑和化療等高影響因子期刊上的發表。她的評論文章《樹狀聚合物毒性：讓我們迎接挑戰》和《樹狀聚合物作為藥物傳遞的納米載體》分別發表在《藥劑學國際期刊》（2010年）和《聚合物科學進展》（2014年），並被列為前25篇文章。她是10本書籍和書籍章節的作者，這些書籍由國際出版商出版。她獲得了多項研究獎學金，包括SERB博士後獎學金、高級研究獎學金（CSIR）、初級研究獎學金（UGC）、年輕科學家培訓獎學金（MPCST）、旅行補助金（INSA）和國際旅行獎學金（ICMR和DBT），以及其他多項著名的獎助金、獎學金和獎項。她曾被提名為2012年Ranbaxy研究學者獎和2015年BioAsia創新獎。她在NIPiCON-2014、國際科學大會-2012、APTI - Jaipur - 2018、SPER-Bangkok - 2019等國際會議上獲得了多項最佳研究報告獎。她是德拉H.S. Gour大學（Sagar，M.P.）藥學科學校友獎-2006的獲得者。至今，她已受邀在多個國內和七個國際會議上展示她的研究工作，包括2012年在新加坡舉行的ICYRAM、2016年在葡萄牙里斯本舉行的生物包埋會議和2019年在曼谷舉行的國際會議。她在Lufthansa影響周的創新理念獎中獲得了最具創新性的想法獎，這是一個著名的國際平台。
