Perinatal Stem Cells: Biology, Manufacturing and Translational Medicine
暫譯: 圍產期幹細胞:生物學、製造與轉譯醫學

Han, Zhong Chao, Takahashi, Tsuneo A., Han, Zhibo

  • 出版商: Springer
  • 出版日期: 2019-03-25
  • 售價: $4,200
  • 貴賓價: 9.5$3,990
  • 語言: 英文
  • 頁數: 173
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 9811327025
  • ISBN-13: 9789811327025
  • 海外代購書籍(需單獨結帳)

商品描述

This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury.

Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be cultured indefinitely ex vivo, and can differentiate into three germ layers, ethical issues, the teratoma formation of ESCs and oncogenic risk of iPSCs are major obstacles to their clinical application. More recently, perinatal stem cells have been isolated from the umbilical cord, Wharton's Jelly, placenta, amniotic membrane and amniotic fluid, which are normally discarded as medical waste. This book, after describing perinatal stem cells in detail, introduces readers to the various types of perinatal stem cells, addressing their characterization, banking, quality control and stability. Importantly, it also reviews the clinical applications of perinatal stem cells to therapy of diseases. Accordingly, it offers a valuable resource for clinicians, researchers and graduate students alike.


商品描述(中文翻譯)

這本書提供了對各類圍產期幹細胞的全面介紹。由於其獨特的再生能力,幹細胞在退行性疾病或損傷的治療中提供了一個有前景的途徑。

目前,出生後細胞來源的限制和擴增效率可能會限制自體幹細胞療法。雖然胚胎幹細胞(ESCs)和誘導多能幹細胞(iPSCs)可以在體外無限期培養,並且能夠分化為三個胚層,但倫理問題、ESCs的畸胎瘤形成以及iPSCs的致癌風險是其臨床應用的主要障礙。最近,圍產期幹細胞已從臍帶、華頓氏膠、胎盤、羊膜和羊水中分離出來,這些通常被視為醫療廢物而被丟棄。本書在詳細描述圍產期幹細胞後,向讀者介紹各類圍產期幹細胞,並探討其特徵、儲存、質量控制和穩定性。重要的是,它還回顧了圍產期幹細胞在疾病治療中的臨床應用。因此,這本書為臨床醫生、研究人員和研究生提供了寶貴的資源。

作者簡介

Zhong Chao Han is a professor and director at the State Key Lab of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences; Tsuneo A Takahashi is a visiting professor at the Institute for Frontier Medical Sciences, Kyoto University; Zhibo Han is an associate professor at the State Key Lab of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences.


作者簡介(中文翻譯)

中超漢是中國醫學科學院血液病研究所實驗血液學國家重點實驗室的教授及主任;高橋常夫是京都大學前沿醫學科學研究所的訪問教授;韓志博是中國醫學科學院血液病研究所實驗血液學國家重點實驗室的副教授。