The Future of Brain Repair: A Realist's Guide to Stem Cell Therapy
暫譯: 大腦修復的未來:現實主義者的幹細胞療法指南
Price, Jack
- 出版商: Summit Valley Press
- 出版日期: 2020-03-24
- 售價: $1,430
- 貴賓價: 9.5 折 $1,359
- 語言: 英文
- 頁數: 288
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 0262043750
- ISBN-13: 9780262043755
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商品描述
A scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimer's disease, and Parkinson's disease.
Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In this book, neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimer's disease, Parkinson's disease, and spinal cord injuries.
Certainly brain disorders are in need of effective treatments. These disorders don't just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because of its structural, functional, and developmental complexity. He examines the self-repairing capacity of blood and gut cells--and the lack of such capacity in the brain; describes the limitations of early brain stem cell therapies for neurodegenerative disorders; and discusses current clinical trials that may lead to the first licensed stem cell therapies for stroke, Parkinson's and macular degeneration. And he describes the real promise of pluripotential stem cells, which can make all the cell types that constitute the body.
New technologies, Price reports, challenge the very notion of cell transplantation, instead seeking to convince the brain itself to manufacture the new cells it needs. Could this be the true future of brain repair?
商品描述(中文翻譯)
一位科學家評估幹細胞療法在治療中風、阿茲海默症和帕金森病等腦部疾病的潛力。
幹細胞療法受到媒體的巨大宣傳,幾乎被賦予了神奇的特質,公眾也想像它能帶來奇蹟般的療效。幹細胞具有生成不同類型新細胞的潛力,並在某些案例中已經顯示出這一點。幹細胞移植能否修復受損的腦部?在這本書中,神經生物學家 Jack Price 評估幹細胞療法在治療中風、阿茲海默症、帕金森病和脊髓損傷等腦部疾病的潛力。
顯然,腦部疾病需要有效的治療。這些疾病不僅會致命,還會使人殘疾,而傳統的藥物療法在治療這些疾病方面並未取得太大成功。Price 解釋說,修復人類大腦是困難的,主要是因為其結構、功能和發展的複雜性。他檢視了血液和腸道細胞的自我修復能力,以及大腦缺乏這種能力的情況;描述了早期幹細胞療法在神經退行性疾病中的局限性;並討論了可能導致首批獲得許可的幹細胞療法的當前臨床試驗,這些療法針對中風、帕金森病和黃斑變性。他還描述了多潛能幹細胞的真正潛力,這些細胞可以生成構成身體的所有細胞類型。
Price 報告指出,新技術挑戰了細胞移植的概念,試圖說服大腦自身製造所需的新細胞。這是否可能是腦部修復的真正未來?