Advancement in the Pathophysiology of Cerebral Stroke
暫譯: 腦中風病理生理學的進展
Patnaik, Ranjana, Tripathi, Amit Kumar, Dwivedi, Ashish
- 出版商: Springer
- 出版日期: 2019-05-23
- 售價: $4,200
- 貴賓價: 9.5 折 $3,990
- 語言: 英文
- 頁數: 189
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 9811314527
- ISBN-13: 9789811314520
海外代購書籍(需單獨結帳)
商品描述
This book provides detailed and comprehensive mechanistic insights of the various risk factors that lead to the ischemic stroke and the novel therapeutic interventions against it. The first section discusses the different ischemic cerebral stroke-induced inflammatory pathways and dysfunctionality of blood-brain barrier. The later sections of the book deals with the role of endoplasmic reticulum stress and mitophagy in cerebral stroke and introduces the different neuroimaging techniques such as Computed tomography (CT), Magnetic resonance imaging (MRI), Positron emission tomography (PET) and Single-Photon emission computed tomography (SPECT) that are used to identify the arterial blockages. The final section comprises of chapters that focus on various neuroprotective strategies and emerging therapeutic interventions for combating stroke pathophysiology. The chapters cover the role of stem cell therapy, the therapeutic effect of low-frequency electromagnetic radiations (LF-EMR), and implications of non-coding RNAs such as micro-RNAs as the biomarkers for diagnosis, prognosis, and therapy in ischemic stroke.
商品描述(中文翻譯)
本書提供了導致缺血性中風的各種風險因素的詳細和全面的機制性見解,以及針對這些風險因素的新型治療干預措施。第一部分討論了不同的缺血性腦中風引起的炎症途徑和血腦屏障的功能障礙。書的後面幾個部分探討了內質網壓力和線粒體自噬在腦中風中的作用,並介紹了用於識別動脈阻塞的不同神經影像技術,如計算機斷層掃描(Computed tomography, CT)、磁共振成像(Magnetic resonance imaging, MRI)、正電子發射斷層掃描(Positron emission tomography, PET)和單光子發射計算機斷層掃描(Single-Photon emission computed tomography, SPECT)。最後一部分包含專注於各種神經保護策略和新興治療干預措施以對抗中風病理生理的章節。這些章節涵蓋了幹細胞療法的作用、低頻電磁輻射(Low-frequency electromagnetic radiations, LF-EMR)的治療效果,以及非編碼RNA(如微小RNA)作為缺血性中風診斷、預後和治療的生物標記的意涵。
作者簡介
Prof. Ranjana Patnaik is a Professor in School of Bio-Medical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi, India. She has thirty-three years of teaching and Research Experience. Till now, she has authored 15 book chapters and more than 150 research articles in various peer-reviewed journals. She is a member of numerous Boards including Board of Governors, Board of studies and Board of Examiners in different Universities and Institutions. She has received a number of Awards such as Rashtriya Gaurav Award (2014), Best Citizen of India Award (2014), Rajiv Gandhi Excellence Awards (2014), National Award 2011 (by Department of Science and Technology, Govt. of India) for Low Cost Multi-use Hearing Aid and Saraswati Samman (2010). She is a life member of eight Scholarly Societies including SFN, IBRO, IAN, IBNS, FICCI, APS, BNA and FENS. Her areas of interests are focused on Stroke, Heat/Cold Stress, Blood-Brain Barrier, Neurotoxicity, Neurodegeneration, and Neuroprotection.
Dr. Amit Kumar Tripathi is a National-Post-Doctoral Fellow (DST-SERB) in Electrophysiology Lab, School of Biomedical Engineering, IIT (BHU), Varanasi, India. He has done his Doctoral Research from Endocrinology Division, CSIR-Central Drug Research Institute, Lucknow, India. His doctoral research was focused on the mechanistic studies to understand the neuroprotection. He has ten years of research experience on rodent models of various neurological disorders such as transient Middle Cerebral Artery Occlusion (tMCAO), cerebral venous sinuses thrombotic (CVST), Traumatic brain injury (TBI) and Parkinson disease. He has published his research work in various peer-reviewed international journals including, Journal of Biomedical Science and Neuroscience Letter.
Dr. Ashish Diwedi is a Research Associate in Skaggs School of Pharmacy & Pharmaceutical Sciences, Colorado University, Anschutz Medical Campus, USA. Previously, he has worked as a Post-Doctoral Scientist in Pineal Research Lab, Department of Zoology, BHU, Varanasi, India. His Doctorate research work from Indian Institute of Toxicology Research (IITR), Lucknow was focused on phototoxicity assessment of different therapeutic drugs and environmental pollutants. He has ten years of research experience in Photosciences and published his research in various reputed journals of Photochemistry & Photobiology, Toxicology, Biomaterials, Hazardous materials etc.
作者簡介(中文翻譯)
蘭賈娜·帕特奈克教授是印度瓦拉納西的印度理工學院(班納拉斯印度大學)生物醫學工程學院的教授。她擁有三十三年的教學和研究經驗。至今,她已撰寫了15篇書章和超過150篇在各種同行評審期刊上發表的研究文章。她是多個委員會的成員,包括不同大學和機構的董事會、學術委員會和考試委員會。她獲得了多項獎項,如國家榮耀獎(2014年)、印度最佳公民獎(2014年)、拉吉夫·甘地卓越獎(2014年)、2011年國家獎(由印度政府科學與技術部頒發)以表彰其低成本多用途助聽器,以及薩拉斯瓦蒂獎(2010年)。她是八個學術社團的終身會員,包括SFN、IBRO、IAN、IBNS、FICCI、APS、BNA和FENS。她的研究興趣集中在中風、熱/冷壓力、血腦屏障、神經毒性、神經退行性變和神經保護等領域。
阿米特·庫馬爾·特里帕提博士是印度瓦拉納西印度理工學院(BHU)生物醫學工程學院電生理實驗室的國家博士後研究員(DST-SERB)。他在印度勒克瑙的中央藥物研究所內分泌學部完成了博士研究。他的博士研究專注於機制研究,以了解神經保護。他在各種神經系統疾病的鼠類模型上擁有十年的研究經驗,包括暫時性大腦中動脈阻塞(tMCAO)、腦靜脈竇血栓(CVST)、創傷性腦損傷(TBI)和帕金森病。他的研究成果已發表在多個國際同行評審期刊上,包括《生物醫學科學期刊》和《神經科學快報》。
阿希什·迪維迪博士是美國科羅拉多大學安舒茨醫學校的斯卡格斯藥學與藥物科學學院的研究助理。此前,他曾在印度瓦拉納西的班納拉斯印度大學動物學系的松果體研究實驗室擔任博士後科學家。他在印度毒理研究所(IITR)完成的博士研究專注於不同治療藥物和環境污染物的光毒性評估。他在光科學領域擁有十年的研究經驗,並在多個著名的光化學與光生物學、毒理學、生物材料、有害材料等期刊上發表了他的研究。