Collagen Mimetic Peptides and Their Biophysical Characterization

Xiao, Jianxi

Collagen Mimetic Peptides and Their Biophysical Characterization
  • 出版商: Springer
  • 出版日期: 2024-08-06
  • 售價: $5,790
  • 貴賓價: 9.5 折 $5,501
  • 語言: 英文
  • 頁數: 226
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 9811019401
  • ISBN-13: 9789811019401

    • 海外代購書籍(需單獨結帳)

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商品描述

This book embarks on an enlightening journey through the molecular landscape of collagen mimic peptides, shedding light on their significance and potential. In the intricate realm of biomolecules, collagen's preeminence as the most abundant protein in the human body, forming the foundational scaffolding of tissues and organs, renders it a subject of profound scientific interest. It explores diverse facets related to collagen mimic peptides, spanning aspects such as bioinformatic analysis, synthetic strategies, pathological collagen targeting, and the construction of homotrimeric, heterotrimeric and self-assembled peptide models. Furthermore, it provides an exhaustive investigation into biophysical techniques, encompassing Circular Dichroism (CD), X-ray crystallography, Nuclear Magnetic Resonance (NMR), Fluorescence, and Raman spectroscopy, thereby empowering researchers to unravel the structural intricacies of these peptides. The book unravels the profound implications of collagen mimic peptides across a spectrum of scientific domains, including protein science, biomaterials, bioanalysis, and beyond. Its accessibility and insights cater not only to seasoned researchers but also to undergraduate and graduate students eager to delve into the complexities of this fundamental protein.

商品描述(中文翻譯)

本書踏上了一段啟發性的旅程，穿越膠原蛋白類似肽的分子景觀，揭示了它們的重要性和潛力。在生物分子的錯綜複雜領域中，膠原蛋白作為人體中最豐富的蛋白質，構成組織和器官的基礎支架，使其成為一個深具科學興趣的研究對象。本書探索了與膠原蛋白類似肽相關的多個方面，包括生物信息學分析、合成策略、病理性膠原蛋白靶向以及同源三聚體、異源三聚體和自組裝肽模型的構建。此外，它還對生物物理技術進行了全面調查，包括圓二色光譜（CD）、X射線晶體學、核磁共振（NMR）、螢光和拉曼光譜，從而使研究人員能夠揭示這些肽的結構細節。本書揭示了膠原蛋白類似肽在蛋白質科學、生物材料、生物分析等多個科學領域的深遠影響。它的易讀性和深入見解不僅適用於經驗豐富的研究人員，也適用於渴望深入研究這一基礎蛋白質的本科生和研究生。

作者簡介

Dr. Jianxi Xiao received his bachelor's degree from Wuhan University in 2003 and completed his Ph.D. at Rutgers University-New Brunswick, New Jersey, in 2009. He pursued postdoctoral research at Rutgers University and subsequently attained a full professorship at Lanzhou University's College of Chemistry and Chemical Engineering in 2012. Dr. Xiao holds the distinguished title of Cuiying Scholar at Lanzhou University and is honored with the prestigious "Feitian Scholar" professorship in Gansu Province. In addition, he serves as Director of Medical Collagen Engineering Research Center in Gansu Province and as Director of Joint Collagen Research Center at Lanzhou University. His research interests encompass the development and characterization of innovative collagen mimic peptides, collagen-targeting peptide probes, and collagen-based biomaterials. Dr. Xiao's extensive work has significantly advanced our comprehension of collagen's structure, function, and pathology, leading to the publication of over 70 academic papers in esteemed journals.

作者簡介(中文翻譯)

肖建西博士於2003年獲得武漢大學學士學位，並於2009年在新澤西州羅格斯大學新布倫斯維克分校完成博士學位。他在羅格斯大學進行博士後研究，並於2012年獲得蘭州大學化學與化工學院的全職教授職位。肖博士在蘭州大學擁有崔英學者的尊榮稱號，並榮獲甘肅省著名的“飛天學者”教授職位。此外，他還擔任甘肅省醫用膠原工程研究中心主任和蘭州大學聯合膠原研究中心主任。他的研究興趣包括創新膠原類似肽、膠原靶向肽探針和基於膠原的生物材料的開發和表徵。肖博士的廣泛研究工作顯著推進了我們對膠原結構、功能和病理的理解，並在著名期刊上發表了70多篇學術論文。

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