Engrams: A Window Into the Memory Trace

Gräff, Johannes, Ramirez, Steve

Engrams: A Window Into the Memory Trace
  • 出版商: Springer
  • 出版日期: 2024-07-16
  • 售價: $7,780
  • 貴賓價: 9.5 折 $7,391
  • 語言: 英文
  • 頁數: 328
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 3031629825
  • ISBN-13: 9783031629822

    • 海外代購書籍(需單獨結帳)

相關主題

商品描述

This is the first book to extensively explore the current state-of-the-art and promise of engram cells, the closest physical approximation of the memory trace to date. Converging evidence suggests that memories are stored, at least in part, as specific populations of engram cells. In this book, the leading experts in engram biology share their continuously refined insights on how engram cells contribute to information encoding and storage, across diverse brain regions and behavioral modalities. "Engrams: A Window into the Memory Trace" is broad in scope and spans molecular, cellular, circuit, computational as well as societal-philosophical aspects of memory engrams. Particular emphasis is placed on their emerging translational value for memory dysfunctions in age and stress-related disorders.

商品描述(中文翻譯)

這是第一本廣泛探索記憶痕跡的最新狀態和前景的書籍，它介紹了到目前為止最接近記憶痕跡的物理近似物——記憶細胞。匯集的證據表明，記憶至少部分地以特定的記憶細胞群體形式儲存。在這本書中，記憶細胞生物學的領先專家分享了他們對記憶細胞如何在不同腦區和行為模式中貢獻於資訊編碼和儲存的不斷精煉的見解。《記憶痕跡的窗口：記憶細胞》的範圍廣泛，涵蓋了分子、細胞、電路、計算以及社會哲學等記憶痕跡的各個方面。特別強調了它們在年齡和壓力相關疾病的記憶功能障礙中的新興轉譯價值。

作者簡介

Johannes Gräff, PhD, is Associate Professor and Director of the Laboratory of Neuroepigenetics at the Brain Mind Institute of the Ecole Polytechnique Federale de Lausanne (EPFL) in Lausanne, Switzerland. Trained as a biologist at the University of Lausanne, Johannes Gräff obtained his PhD in Neuroscience at ETH Zurich before pursuing his postdoctoral studies at the Picower Institute of Learning and Memory at the Massachusetts Institute of Technology in Boston, USA. His laboratory studies the molecular underpinnings of memory formation, storage and change, with a particular emphasis on epigenetic mechanisms.

Steve Ramirez is an Associate Professor of Psychological and Brain Sciences at Boston University and a former Junior Fellow of Harvard University. He received his B.A. in neuroscience from Boston University and went on to receive his Ph.D. in neuroscience at MIT. His lab focuses on imaging and manipulating memories throughout the mammalian brain, with a particular emphasis on artificially modulating memories to alleviate symptoms associated with pathologies of the brain.

作者簡介(中文翻譯)

Johannes Gräff博士是瑞士洛桑洛桑聯邦理工學院（EPFL）腦心研究所神經表觀遺傳學實驗室的副教授和主任。他在洛桑大學接受生物學培訓，並在瑞士聯邦理工學院（ETH Zurich）獲得神經科學博士學位，然後在美國波士頓麻省理工學院（MIT）的皮科爾學習與記憶研究所進行博士後研究。他的實驗室研究記憶形成、儲存和變化的分子基礎，特別強調表觀遺傳機制。

Steve Ramirez是波士頓大學心理與腦科學副教授，曾是哈佛大學的初級研究員。他在波士頓大學獲得神經科學學士學位，並在麻省理工學院獲得神經科學博士學位。他的實驗室專注於在哺乳動物大腦中成像和操縱記憶，特別強調人工調節記憶以緩解與腦部病理相關的症狀。

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