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商品描述
The book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions and novel approaches for efficient drug delivery to the brain (e.g., pharmaceutical nanocarriers and transporter- and transcytosis-mediated drug delivery to the brain inhibition of the blood-brain barrier). Chapters dealing with state-of-the-art in silico and in vitro tools for predictive purposes related to CNS bioavailability are also be included.
This is an ideal book for undergraduate students and graduates in the field of medicine and pharmaceutics, and professionals working in the field of brain disorders.
商品描述(中文翻譯)
這本書涵蓋了中樞神經系統治療領域的最新進展,包括與中樞神經系統疾病相關的基礎知識擴展和有效藥物傳遞到大腦的新方法(例如,藥物納米載體和藥物通過載體和跨膜運輸傳遞到大腦,以及對血腦屏障的抑制)。書中還包括了關於預測中樞神經系統生物利用度的最新計算模擬和體外工具的章節。
這本書非常適合醫學和藥學領域的本科生和研究生,以及從事腦部疾病相關工作的專業人士。
作者簡介
Prof. Alan Talevi was born in Buenos Aires, 1980. He obtained his Pharmacy degree in 2004 and completed his PhD studies in 2007, both at the University of La Plata (UNLP, Argentina). Among other recognitions, he obtained the award for the best PhD thesis on Computational Chemistry from the Argentinean Chemical Society (2008), a Pacifichem Young Scholar Award (USA, 2010) and the Award to Scientific and Technological Production from UNLP (2016). Since 2010, he holds a permanent position at the Argentinean Council of Scientific and Technical Research (CONICET), where he currently occupies a Principal Researcher position, and he is a Full Professor (tenured) in charge of the Biopharmacy/Pharmacokinetics course at the Faculty of Exact Sciences, UNLP. He has published over 100 articles in periodicals and more than 80 book chapters/entries, mostly in the fields of machine learning, drug discovery and biopharmaceutics.
作者簡介(中文翻譯)
Prof. Alan Talevi於1980年出生於阿根廷布宜諾斯艾利斯。他於2004年獲得藥學學位,並於2007年完成博士學位,兩者均在拉普拉塔大學(阿根廷)取得。他獲得了阿根廷化學學會(2008年)頒發的計算化學最佳博士論文獎,以及Pacifichem Young Scholar Award(2010年)和拉普拉塔大學(2016年)的科學與技術生產獎等多項殊榮。自2010年以來,他在阿根廷科學與技術研究委員會(CONICET)擔任永久職位,目前擔任首席研究員職位,並在拉普拉塔大學精確科學學院擔任全職教授,負責生物藥學/藥物動力學課程。他在機器學習、藥物發現和生物藥學等領域發表了100多篇期刊文章和80多篇專書章節/條目。