Anti-Neutrophil Cytoplasmic Antibody (Anca) Associated Vasculitis
暫譯: 抗中性粒細胞胞漿抗體（ANCA）相關血管炎

Sinico, Renato Alberto, Guillevin, Loic

Anti-Neutrophil Cytoplasmic Antibody (Anca) Associated Vasculitis
  • 出版商: Springer
  • 出版日期: 2019-10-01
  • 售價: $4,890
  • 貴賓價: 9.5 折 $4,646
  • 語言: 英文
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 3030022382
  • ISBN-13: 9783030022389

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商品描述

 

This volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others.

The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area.

 

 

The book is part of Springer's series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. AAVs are systemic autoimmune diseases of unknown cause that affect small (to medium) sized blood vessels. They include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome).

 

This volume will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these diseases.

 

 

 

商品描述(中文翻譯)

本卷由該領域的知名專家撰寫，涵蓋了抗中性粒細胞胞漿抗體（Anti-Neutrophil Cytoplasmic Antibody, ANCA）相關血管炎（AAV）的所有方面。這個表達指的是一組疾病，其特徵是小血管的破壞和炎症。臨床症狀各異，影響多個器官，如腎臟、肺、皮膚、神經系統等。

開篇章節提供了一些歷史背景，解釋了該疾病的遺傳基礎，並根據最近的實驗研究提供了對病因學的見解，指導讀者了解分類和命名法。書中有很大一部分專門用於詳細描述相關的特定疾病及其臨床表現、疾病過程和潛在併發症。關於治療的建議是基於目前在這個不斷發展的領域中可用的最佳證據。

本書是Springer系列《免疫系統罕見疾病》的一部分，該系列呈現了最近獲得的有關病因學、診斷和治療的知識，旨在促進對這些疾病的更全面的理解。AAV是原因不明的系統性自體免疫疾病，影響小（至中）型血管。它們包括肉芽腫性多血管炎（前稱為韋根氏肉芽腫）、顯微鏡多血管炎和嗜酸性肉芽腫性多血管炎（前稱為楚爾格-施特勞斯綜合症）。

本卷將成為所有參與這些疾病患者護理的從業者的重要資訊來源。

作者簡介

Renato Alberto Sinico is a Professor of Nephrology and Director of the Postgraduate School of Nephrology at Università degli Studi di Milano - Bicocca. From 2005 to 2015 he was responsible for the Clinical Immunology Unit at Ospedale San Carlo Borromeo of Milan, where he has worked since 1980. He has been president of Forum Interdisciplinare delle Malattie Autoimmuni (FIRMA) and secretary of Immunopathology Study Group of the Italian Society of Nephrology. With a special interest in kidney failure, glomerulonephritis, vasculitis, lupus, cryoglobulinemia, rare autoimmune diseases, autoantibodies such as ANCA and anti-DNA, Prof. Sinico works with numerous international journals, and is the author of more than 160 scientific publications.

 


Loïc Guillevin is a specialist in internal medicine, involved for many years in the management and care of patients affected by systemic vasculitides, like eosinophilic granulomatosis with polyangitis syndrome, but also granulomatous polyangitis granulomatosis, classical or hepatitis B virus (HBV)-related polyarteritis nodosa, microscopic polyangiitis or mixed essential cryoglobulinemia. Founder of the French Vasculitis Study Group (FVSG) counting over 600 French physicians and with strong international contacts. More than 20 prospective therapeutic trials have been conducted so far by the FVSG, with subsequent publications in renowned international medical journals, with major practical findings: the most severe forms of the disease, identified as those having specific renal, cardiac, gastrointestinal and/or central nervous system involvement, should receive a combination of corticosteroids and immunosuppressant, mostly monthly cyclophosphamide pulses. Pr Loïc Guillevin and his main collaborators are currently based in the Department of Internal Medicine, Hôpital Cochin, Université Paris 5, Paris, France. In 2003 the FVSG created its web homepage, primarily dedicated to continuing medical education, but the development of a patients' homepage, with the help of patients and patients' associations, is planned for the very near future.

 

作者簡介(中文翻譯)

Renato Alberto Sinico 是米蘭比可卡大學（Università degli Studi di Milano - Bicocca）腎臟病學教授及腎臟病學研究所所長。從2005年到2015年，他負責米蘭聖卡洛博羅梅奧醫院（Ospedale San Carlo Borromeo）的臨床免疫學單位，自1980年以來一直在該醫院工作。他曾擔任自體免疫疾病跨學科論壇（Forum Interdisciplinare delle Malattie Autoimmuni, FIRMA）主席及意大利腎臟學會免疫病理學研究小組秘書。Sinico教授特別關注腎衰竭、腎小球腎炎、血管炎、紅斑狼瘡、冷球蛋白血症、罕見自體免疫疾病、自體抗體如ANCA和抗DNA，並與多本國際期刊合作，發表超過160篇科學出版物。



Loïc Guillevin 是內科專家，長期參與系統性血管炎患者的管理和護理，如嗜酸性肉芽腫性多血管炎綜合症，以及肉芽腫性多血管炎、經典或與乙型肝炎病毒（HBV）相關的多發性動脈炎、顯微鏡多血管炎或混合性冷球蛋白血症。他是法國血管炎研究小組（French Vasculitis Study Group, FVSG）的創始人，該小組擁有超過600名法國醫生，並與國際上有著密切的聯繫。FVSG迄今已進行超過20項前瞻性治療試驗，並在知名國際醫學期刊上發表了相關研究，得出了重要的實踐發現：最嚴重的疾病形式，特別是那些具有特定腎臟、心臟、消化道和/或中樞神經系統受累的患者，應接受以皮質類固醇和免疫抑制劑（主要是每月的環磷酰胺脈衝）為主的組合治療。Loïc Guillevin教授及其主要合作者目前在法國巴黎第五大學（Université Paris 5）科欣醫院（Hôpital Cochin）內科部門工作。2003年，FVSG創建了其網站首頁，主要用於持續醫學教育，但計劃在不久的將來開發一個患者專屬的首頁，並在患者及患者協會的幫助下進行。

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