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Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines (Immunomics Reviews:)
暫譯: 免疫組學發現佐劑及候選亞單位疫苗(免疫組學評論:)

  • 出版商: Springer
  • 出版日期: 2015-01-28
  • 售價: $6,930
  • 貴賓價: 9.5$6,584
  • 語言: 英文
  • 頁數: 324
  • 裝訂: Paperback
  • ISBN: 1489997954
  • ISBN-13: 9781489997951
  • 海外代購書籍(需單獨結帳)

商品描述

This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.

商品描述(中文翻譯)

本卷將探討免疫組學領域中的一個重要新興領域:在逆向疫苗學(reverse vaccinology)背景下發現抗原和佐劑。傳統的疫苗設計和開發方法需要在實驗室中培養病原體,並識別其中的免疫原性分子。傳統疫苗學不再普遍成功,特別是對於難以處理的病原體。通過使用基因組信息,我們可以在計算機中研究疫苗開發:逆向疫苗學可以通過識別抗原性蛋白來確定候選亞單位疫苗,並通過同樣合理的方法來識別新型的增強免疫反應的佐劑。

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