Chemogenomics: Methods and Protocols
暫譯: 化學基因組學:方法與實驗步驟

Merk, Daniel, Chaikuad, Apirat

  • 出版商: Humana Press
  • 出版日期: 2024-08-11
  • 售價: $6,400
  • 貴賓價: 9.5$6,080
  • 語言: 英文
  • 頁數: 234
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 1071633996
  • ISBN-13: 9781071633991
  • 無法訂購

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商品描述

This volume presents both theoretical guidance and protocols on chemogenomics including chemogenomics library assembly, compound profiling, and phenotypic assays. The chapters in this book cover topics such as the assembly and use of Kinase Chemogenomics; data mining for chemogenomic compound candidates; protocols for protein family-focused assay systems to profile chemogenomic compounds; functional and target engagement assays in cellular settings for broad characterization; and a discussion on phenotypic assays where chemogenomic sets may be applied. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Chemogenomics: Methods and Protocols is a valuable resource for all researchers whoare interested in learning more about this diverse and developing field.

商品描述(中文翻譯)

本卷提供了有關化學基因組學的理論指導和實驗流程,包括化學基因組學文庫的組建、化合物特徵分析和表型測試。本書的章節涵蓋了以下主題:激酶化學基因組學的組建和使用;化學基因組化合物候選者的數據挖掘;針對蛋白質家族的測試系統以分析化學基因組化合物的實驗流程;在細胞環境中進行的功能性和靶標參與測試以進行廣泛的特徵描述;以及關於表型測試的討論,這些測試可以應用化學基因組學集。這本書採用成功的《分子生物學方法》(Methods in Molecular Biology)系列格式編寫,章節包括各自主題的介紹、所需材料和試劑的清單、逐步的可重複實驗流程,以及故障排除和避免已知陷阱的提示。

《化學基因組學:方法與流程》(Chemogenomics: Methods and Protocols)內容前沿且全面,是所有對這個多樣且不斷發展的領域感興趣的研究者的寶貴資源。

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