Chemogenomics: Methods and Protocols
Merk, Daniel, Chaikuad, Apirat
- 出版商: Humana Press
- 出版日期: 2024-08-11
- 售價: $6,210
- 貴賓價: 9.5 折 $5,900
- 語言: 英文
- 頁數: 234
- 裝訂: Quality Paper - also called trade paper
- ISBN: 1071633996
- ISBN-13: 9781071633991
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商品描述
This volume presents both theoretical guidance and protocols on chemogenomics including chemogenomics library assembly, compound profiling, and phenotypic assays. The chapters in this book cover topics such as the assembly and use of Kinase Chemogenomics; data mining for chemogenomic compound candidates; protocols for protein family-focused assay systems to profile chemogenomic compounds; functional and target engagement assays in cellular settings for broad characterization; and a discussion on phenotypic assays where chemogenomic sets may be applied. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and thorough, Chemogenomics: Methods and Protocols is a valuable resource for all researchers whoare interested in learning more about this diverse and developing field.
Cutting-edge and thorough, Chemogenomics: Methods and Protocols is a valuable resource for all researchers whoare interested in learning more about this diverse and developing field.
商品描述(中文翻譯)
本卷提供了有關化學基因組學的理論指導和實驗流程,包括化學基因組學文庫的組建、化合物特徵分析和表型測試。本書的各章節涵蓋了多個主題,例如激酶化學基因組學的組建和使用;化學基因組化合物候選者的數據挖掘;針對蛋白質家族的測試系統以分析化學基因組化合物的實驗流程;在細胞環境中進行的功能性和靶向結合測試以進行廣泛的特徵描述;以及關於可以應用化學基因組集的表型測試的討論。本書採用成功的《Methods in Molecular Biology》系列格式撰寫,各章節包括對其主題的介紹、所需材料和試劑的清單、逐步的可重複實驗流程,以及故障排除和避免已知陷阱的提示。
《Chemogenomics: Methods and Protocols》是一本前沿且全面的資源,對於所有希望深入了解這一多樣化和發展中的領域的研究人員來說,都是一個寶貴的參考資料。