Carbonic Anhydrases: Biochemistry and Pharmacology of an Evergreen Pharmaceutical Target
暫譯: 碳酸酐酶:常青藥物靶點的生物化學與藥理學

Supuran, Claudiu T., Nocentini, Alessio

  • 出版商: Academic Press
  • 出版日期: 2019-07-18
  • 售價: $8,810
  • 貴賓價: 9.5$8,370
  • 語言: 英文
  • 頁數: 512
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 012816476X
  • ISBN-13: 9780128164761
  • 相關分類: 化學 Chemistry
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

Carbonic Anhydrases provides an interdisciplinary review of the burgeoning carbonic anhydrase (CA) research area, spanning from CAs classification (biochemical and structural features) to drug design and pharmacology of CA inhibitors and activators, finally touching on the biotechnological applications of these metalloenzymes. The book adopts a clear step-by-step approach and introduction to this intricate and highly interdisciplinary field. A diverse range of chapters from international experts speak to CA classification and distribution, the mechanisms of action and drug design of inhibitors and activators, the druggability of the various isoforms in the treatment of a multitude of diseases, and threats to human health. Carbonic Anhydrases provides biology, biochemistry, and medicinal chemistry students and researchers a thorough discussion and update on the evergreen and expanding research area of CAs.

● Offers a full overview of CAs' biochemical and structural features, as well as drug design and pharmacology of inhibitors and activators.
● Provides a thorough update on the newly identified isoforms, modulating chemotypes, and innovative biomedical applications.
● Describes the current biotechnological applications of CAs, including processes for CO2 capture.
● Features chapter contributions from international leaders in CA biology, medicinal chemistry, and pharmacology.

商品描述(中文翻譯)

《碳酸酐酶》提供了一個跨學科的回顧,涵蓋了不斷增長的碳酸酐酶(CA)研究領域,從CA的分類(生化和結構特徵)到CA抑制劑和激活劑的藥物設計和藥理學,最後觸及這些金屬酶的生物技術應用。這本書採用清晰的逐步方法和介紹,進入這個錯綜複雜且高度跨學科的領域。來自國際專家的多樣化章節探討了CA的分類和分佈、抑制劑和激活劑的作用機制及藥物設計、各種亞型在治療多種疾病中的藥物可行性,以及對人類健康的威脅。《碳酸酐酶》為生物學、生物化學和藥物化學的學生和研究人員提供了對這一持續增長的CA研究領域的全面討論和最新資訊。

● 提供CA的生化和結構特徵的全面概述,以及抑制劑和激活劑的藥物設計和藥理學。
● 提供對新識別的亞型、調節化學類型和創新生物醫學應用的徹底更新。
● 描述CA的當前生物技術應用,包括二氧化碳捕集的過程。
● 特色章節由CA生物學、藥物化學和藥理學的國際領導者貢獻。