The Autoimmune Diseases
暫譯: 自體免疫疾病

Rose, Noel R., MacKay, Ian R.

The Autoimmune Diseases
  • 出版商: Academic Press
  • 出版日期: 2019-11-11
  • 售價: $11,230
  • 貴賓價: 9.5 折 $10,669
  • 語言: 英文
  • 頁數: 1532
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0128121025
  • ISBN-13: 9780128121023

    • 海外代購書籍(需單獨結帳)

商品描述

The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments.

The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.

商品描述(中文翻譯)

《自體免疫疾病，第六版》強調21世紀醫學的「三個P」：精準、預測和預防。內容涵蓋現代生物學的系統方法，涉及大量個性化的持續生理數據（「組學」），結合先進的分析方法、新的基因工程檢測技術，如CRISPR、自體炎症疾病、自體免疫對腫瘤免疫療法的反應，以及正常免疫反應和疾病的相關資訊。每一種主要的自體免疫疾病均由經驗豐富的研究人員和臨床研究者討論，他們在處理患者方面具有豐富的經驗。各章節強調疾病的免疫學基礎，以及免疫學診斷方法和治療的應用。

本書還涵蓋了與自體免疫疾病的識別和治療相關的幾個交叉議題，包括自體抗體和T細胞的測量、作為疾病早期預測指標的生物標記物的使用，以及新的治療方法。

目錄大綱

Section 1: Immunologic Basis of Autoimmunity
1. Prelude: Historical introduction to autoimmunity and autoimmune disease
2. Structural and Functional Aspects of the Innate and Adaptive Systems of Immunity
3. General Features of Autoimmune Diseases
4. Antigen Presentation, Dendritic Cells, and Autoimmunity
5. T cells and their subsets
6. Role of Th1 Th2 Th17 Cells in Autoimmunity
7. Tolerance and Autoimmunity: T Cells
8. Regulatory T Cells
9. B Cells and Autoimmunity
10. Immunological memory T cells
11. Immunological memory B cells 12. Apoptotic Cells as a Source of Autoantigens
13. Effector Mechanisms of Autoimmunity: Antibodies and Immune Complexes
14. Functional Effects of Autoantibodies
15. Cytokine Chemokines
16. Signaling Pathways in T and B Lymphocytes
17. HLA Genetics and Autoimmunity
18. Non HLA Genetics
19. AIRE related Autoimmunity
20. Immune Deficiencies and Autoimmunity
21. Infections and Autoimmunity
22. Noninfectious Environmental Agents and Autoimmunity
23. Sex, Pregnancy and Autoimmunity
24. Animal Models of Autoimmune Disease

Section 2: Multisystem Diseases
25. Systemic Lupus Erythematosus
26. Systemic Sclerosis, Scleroderma
27. Antiphospholipid Syndrome
28. Sjogren Syndrome
29. Rheumatoid Arthritis
30. Spondyloarthritis and Chronic Idiopathic Arthropathies
31. Myositis
32. Thyroid Disease
33. Type 1 Diabetes
34. Adrenalitis
35. Polyendocrine Syndromes
36. Gastritis and Pernicious Anemia
37. Hypophysitis
38. Hemolytic Anemia
39. Thrombocytopenic Purpura
40. Neutropenia
41. Aplastic Anemia
42. Clotting Disorders
43. Multiple Sclerosis
44. Peripheral Neuropathy
45. Myasthenia Gravis
46. Ocular Disease
47. Inner Ear Disease
48. Celiac Disease
49. Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn’s Disease
50. Chronic Hepatitis
51. Primary Billiary Cirrhosis
52. Primary Sclerosing Cholangitis
53. Pancreatitis
54. Bullous Skin Diseases: Pemphigus and Pemphigoid
55. Non-Bullous Skin Diseases: Alopecia, Vitiligo, Psoriasis and Urticaria
56. Kidney Disease: Goodpasture’s Disease, Lupus Nephritis, ANCA-Associated Glomerulonephritis
57. Orchitis and Male Infertility
58. Oophoritis
59. Rheumatic Heart Disease
60. Myocarditis and Dilated Cardiomyopathy
61. Necrotizing Arteritis and Small Vessel Vasculitis
62. Large and Medium Vessel Vasculitides
63. Autoimmune Disorders of the Lung
64. Paraneoplastic Diseases
65. Antibody-Associated Neurological Diseases
66. Autoinflammatory and other Related Diseases

Section 3: Diagnosis, Prevention, and Therapy
67. Autoantibody Assays, Testing, and Standardization
68. Prediction of Autoimmune Disease
69. Emerging Therapies for Autoimmune Diseases
70. Postlude 

目錄大綱(中文翻譯)

Section 1: Immunologic Basis of Autoimmunity

1. Prelude: Historical introduction to autoimmunity and autoimmune disease

2. Structural and Functional Aspects of the Innate and Adaptive Systems of Immunity

3. General Features of Autoimmune Diseases

4. Antigen Presentation, Dendritic Cells, and Autoimmunity

5. T cells and their subsets

6. Role of Th1 Th2 Th17 Cells in Autoimmunity

7. Tolerance and Autoimmunity: T Cells

8. Regulatory T Cells

9. B Cells and Autoimmunity

10. Immunological memory T cells

11. Immunological memory B cells 12. Apoptotic Cells as a Source of Autoantigens

13. Effector Mechanisms of Autoimmunity: Antibodies and Immune Complexes

14. Functional Effects of Autoantibodies

15. Cytokine Chemokines

16. Signaling Pathways in T and B Lymphocytes

17. HLA Genetics and Autoimmunity

18. Non HLA Genetics

19. AIRE related Autoimmunity

20. Immune Deficiencies and Autoimmunity

21. Infections and Autoimmunity

22. Noninfectious Environmental Agents and Autoimmunity

23. Sex, Pregnancy and Autoimmunity

24. Animal Models of Autoimmune Disease

Section 2: Multisystem Diseases

25. Systemic Lupus Erythematosus

26. Systemic Sclerosis, Scleroderma

27. Antiphospholipid Syndrome

28. Sjogren Syndrome

29. Rheumatoid Arthritis

30. Spondyloarthritis and Chronic Idiopathic Arthropathies

31. Myositis

32. Thyroid Disease

33. Type 1 Diabetes

34. Adrenalitis

35. Polyendocrine Syndromes

36. Gastritis and Pernicious Anemia

37. Hypophysitis

38. Hemolytic Anemia

39. Thrombocytopenic Purpura

40. Neutropenia

41. Aplastic Anemia

42. Clotting Disorders

43. Multiple Sclerosis

44. Peripheral Neuropathy

45. Myasthenia Gravis

46. Ocular Disease

47. Inner Ear Disease

48. Celiac Disease

49. Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn’s Disease

50. Chronic Hepatitis

51. Primary Billiary Cirrhosis

52. Primary Sclerosing Cholangitis

53. Pancreatitis

54. Bullous Skin Diseases: Pemphigus and Pemphigoid

55. Non-Bullous Skin Diseases: Alopecia, Vitiligo, Psoriasis and Urticaria

56. Kidney Disease: Goodpasture’s Disease, Lupus Nephritis, ANCA-Associated Glomerulonephritis

57. Orchitis and Male Infertility

58. Oophoritis

59. Rheumatic Heart Disease

60. Myocarditis and Dilated Cardiomyopathy

61. Necrotizing Arteritis and Small Vessel Vasculitis

62. Large and Medium Vessel Vasculitides

63. Autoimmune Disorders of the Lung

64. Paraneoplastic Diseases

65. Antibody-Associated Neurological Diseases

66. Autoinflammatory and other Related Diseases

Section 3: Diagnosis, Prevention, and Therapy

67. Autoantibody Assays, Testing, and Standardization

68. Prediction of Autoimmune Disease

69. Emerging Therapies for Autoimmune Diseases

70. Postlude 

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