Staphylococcus Aureus: Interplay Between Bacteria and Hosts

Akio Nakane is emeritus professor at Hirosaki University, specially appointed professor at Hirosaki University Graduate School of Medicine, and professor at Hirosaki University of Health and Welfare, Hirosaki, Aomori, Japan. With expertise in bacteriology, virology and immunology, Nakane investigated roles of cytokines including interferons (IFNs) in infections with Listeria monocytogenes, Staphylococcus aureus and Theiler's murine encephalomyelitis virus at Hokkaido University Graduate School of Medicine, Sapporo, Japan (1976-1994). Nakane verified that the essential roles of TNF-a and IFN-g in innate and adaptive defense against L. monocytogenes infection. After transfer to Hirosaki University Graduate School of Medicine (1994-), Nakane noticed staphylococcal superantigenic toxins and his project developed toxic shock syndrome toxin-1 (TSST-1) vaccine against S. aureus infection with Prof. Hu and also clarified novel functions of TSST-1 with Prof. Asano and an emetic mechanism of staphylococcal enterotoxin A using house musk shrew and common marmoset.

Krisana Asano

Krisana Asano is a professor at Hirosaki University Graduate School of Medicine in Hirosaki, Aomori Prefecture, Japan. With expertise in molecular biology and genetic engineering, Asano brings a wealth of experience in bacteria-host interactions to her work with the team of Professor Akio Nakane. With over fifteen years' experiences, Asano has a proven track record of publishing papers on bacterial infection mechanisms, particularly on Listeria monocytogenes and Staphylococcus aureus infections. Based on the intracellular survival mechanism of bacteria, Asano specializes in immune invasion and autophagy interaction to S. aureus. Her expertise and enthusiastic approach enhance the quality of this book, providing readers with profound insights and knowledge.

中根明夫
中根明夫是日本青森縣弘前市的弘前大學名譽教授，弘前大學醫學研究所特聘教授，以及弘前健康福祉大學的教授。中根教授在細菌學、病毒學和免疫學方面具有專業知識，曾在日本北海道大學醫學研究所進行研究，探討細菌感染中細胞激素（包括干擾素）在與李斯特菌、金黃色葡萄球菌和Theiler's小鼠腦脊髓炎病毒感染中的作用（1976-1994）。中根教授證實了TNF-a和IFN-g在對李斯特菌感染的先天和適應性防禦中的重要作用。在轉到弘前大學醫學研究所後（1994年至今），中根教授注意到金黃色葡萄球菌超抗原毒素，並與胡教授合作開發了針對金黃色葡萄球菌感染的致命性休克綜合症毒素-1（TSST-1）疫苗，並與浅野教授一起澄清了TSST-1的新功能，以及金黃色葡萄球菌肠毒素A的催吐機制，使用了家鼠和普通狨猴進行研究。

浅野克紗奈
浅野克紗奈是日本青森縣弘前市的弘前大學醫學研究所的教授。浅野教授在分子生物學和基因工程方面具有專業知識，並與中根明夫教授的團隊合作，致力於細菌與宿主的相互作用研究。浅野教授擁有超過十五年的經驗，在細菌感染機制方面發表了多篇論文，尤其是關於李斯特菌和金黃色葡萄球菌感染。基於細菌的細胞內存活機制，浅野教授專注於免疫入侵和自噬與金黃色葡萄球菌的相互作用。她的專業知識和熱情的態度提升了本書的質量，為讀者提供深入的見解和知識。