The Quintessence of Basic and Clinical Research and Scientific Publishing

這本書旨在幫助生物醫學研究者，試圖促進對影響科學研究的各種元素的全面理解，例如臨床試驗設計、溝通和出版方法。

書中介紹了創意生成和創造性/批判性思維的過程，導致關鍵概念的發展，這些概念最終凝聚成理論構想和工作假設。該書系統性地劃分了與從實驗室到臨床轉化方法相關的研究階段，提供了藥物發現和開發的全面深度和廣度：設計、合成和優化與疾病相關的靶點互動的藥物候選物，以及臨床試驗設計，以獲取針對目標病人群體的候選藥物的有效性和安全性的重要證據。

書中還納入了新興和發展中的主題，如人工智慧、機器學習和深度學習、藥物再利用方法以及生物資訊學，因為這些特徵正逐漸融入藥物研究和開發中。此外，書中涵蓋了出版策略，包括文獻搜尋、手稿準備、數據呈現、相關討論、編輯過程、同行評審的要素以及文獻計量學。最後，該書探討了撰寫研究經費的技巧、建立有效網絡的關鍵策略、導師制度、維持研究誠信以及創造職業發展機會，包括創業。

Gowraganahalli Jagadeesh, Ph.D. has worked for more than three decades for the US Food and Drug Administration as a Senior Expert Pharmacologist in the Office of Cardiology, Hematology, Endocrinology, and Nephrology at the Center for Drug Evaluation and Research. He was an Adjunct Scientist at the NIH, Bethesda while working at the FDA. He had also taught at Banaras Hindu University, Varanasi, India, and was a Canadian Heart Foundation Fellow and NIH staff scientist (at Northeastern University, Boston). Dr. Jagadeesh received B. Pharm, MSc and Ph.D. degrees from RGUS-Bengaluru, All-India Institute of Medical Sciences-Delhi, and BHU, respectively. He is currently a Distinguished Visiting Professor at College of Pharmaceutical Sciences, Dayananda Sagar University, Bengaluru; and a visiting professor at College of Pharmacy, Adichunchanagiri University, BG Nagara, Karnataka; and College of Pharmaceutical Sciences, Manipal Academy of Higher Education (Deemed-to-be University), Manipal, India. More than 60 scientific papers, including book chapters, have been authored by him, and he has edited three books as well.

Pitchai Balakumar, M.Pharm., Ph.D. is working as Professor & Director, Centre for Scholarly Scientific Training and Publishing, The Office of Research and Development, Periyar Maniammai Institute of Science & Technology (Deemed-to-be University), Vallam, Tamil Nadu, India. Previously, he was a Professor of Pharmacology at King Khalid University, Saudi Arabia, and Senior Associate Professor and Head of Pharmacology Unit at the Faculty of Pharmacy, AIMST University, Malaysia. He was the Visiting Scientist at the University of Montreal, Canada in 2009. Prof. Balakumar's name has been featured, for the third consecutive time (since 2020), among the World Ranking Top 2% Scientists in the Field: Pharmacology & Pharmacy, based on a study done by Stanford University scientists. He obtained M.Pharm and Ph.D. degrees in Pharmacology specialized in Cardiovascular Pharmacology from Punjabi University-Patiala, Punjab, India. He has two decades of teaching, research and editorial experience in the field of Cardiovascular-Renal Sciences, and trained several graduates in India and abroad. He has published around 125 scientific papers (over 5350 citations with h-index 40), and received several awards and honors for excellence in overall academic and research performance. Along with two senior scientists from the US FDA, Prof. Balakumar edited a reference book titled 'Pathophysiology and Pharmacotherapy of Cardiovascular Disease' published by Springer in 2015. He also edited a number of focused Special Issues in cardiovascular sciences. Prof. Balakumar is a 'Consulting Editor' at Pharmacological Research-Elsevier.

Fortunato Fred Senatore, MD, PhD, FACC received his bachelor degree in biochemistry and master degree in biomedical engineering from Columbia University, and Ph.D. in chemicalengineering from Rutgers University. He served as an assistant professor of chemical engineering at Texas Tech University and focused on artificial organ research and biocompatible prostheses. He attended medical school at the Texas Tech University School of Medicine during his tenure at the Texas Tech University School of Engineering. He trained in Internal Medicine at the Mayo Clinic and Cardiology at Harvard University-Massachusetts General Hospital. He served in the pharmaceutical industry with increasing levels of responsibility for 17 years where he conducted and supervised clinical research in cardiovascular disease, renal disease, and endocrinology. He subsequently joined the FDA in the Division of Cardiology and Nephrology and has been serving as Medical Officer since 2012. For the past four years, he has been serving as Lead Physician.

Gowraganahalli Jagadeesh, Ph.D. 在美國食品藥品監督管理局工作超過三十年，擔任心臟病學、血液學、內分泌學和腎臟病學辦公室的高級專家藥理學家，隸屬於藥物評估與研究中心。在FDA工作期間，他曾擔任國立衛生研究院（NIH）貝塞斯達的兼任科學家。他也曾在印度瓦拉納西的班納拉斯印度大學任教，並曾是加拿大心臟基金會的研究員及NIH的職員科學家（在波士頓的東北大學）。Jagadeesh博士分別在RGUS-班加羅爾、全印度醫學科學院-德里和班納拉斯印度大學獲得藥學學士、碩士及博士學位。他目前是班加羅爾達亞南達薩加大學藥學院的特聘訪問教授；同時也是卡納塔克邦阿迪丘恩查那吉里大學藥學院的訪問教授，以及印度馬尼帕爾高等教育學院（被認定為大學）的藥學院的訪問教授。他已發表超過60篇科學論文，包括書籍章節，並編輯了三本書籍。

Pitchai Balakumar, M.Pharm., Ph.D. 擔任印度泰米爾納德邦佩里亞爾馬尼安邁科技學院（被認定為大學）學術科學訓練與出版中心的教授及主任。此前，他曾在沙烏地阿拉伯的哈立德王大學擔任藥理學教授，以及在馬來西亞AIMST大學藥學院擔任高級副教授及藥理學單位主任。他於2009年擔任加拿大蒙特利爾大學的訪問科學家。根據史丹佛大學科學家的研究，Balakumar教授的名字自2020年以來第三次連續出現在世界排名前2%的藥理學與藥學領域科學家名單中。他在印度旁遮普大學-帕提亞拉獲得心血管藥理學專業的藥學碩士及博士學位。他在心血管-腎臟科學領域擁有二十年的教學、研究及編輯經驗，並培訓了多位國內外的畢業生。他已發表約125篇科學論文（引用次數超過5350次，h指數40），並因其卓越的學術及研究表現獲得多項獎項和榮譽。與兩位美國FDA的高級科學家共同編輯了2015年由Springer出版的參考書籍《心血管疾病的病理生理學與藥物治療》。他還編輯了多個心血管科學的專題特刊。Balakumar教授是《藥理學研究-Elsevier》的顧問編輯。

Fortunato Fred Senatore, MD, PhD, FACC 獲得哥倫比亞大學的生物化學學士學位和生物醫學工程碩士學位，並在羅格斯大學獲得化學工程博士學位。他曾擔任德州科技大學的化學工程助理教授，專注於人工器官研究和生物相容性假體。在德州科技大學工程學院任職期間，他也就讀於德州科技大學醫學院。他在梅奧診所接受內科訓練，並在哈佛大學-麻薩諸塞州總醫院接受心臟病學訓練。他在製藥行業工作了17年，負責臨床研究，專注於心血管疾病、腎臟疾病和內分泌學，並逐步提升職位。隨後，他加入FDA的心臟病學和腎臟病學部門，自2012年以來擔任醫療官員。在過去四年中，他擔任首席醫生。