Epigenetic Mechanisms of Cell Programming and Reprogramming

Pei, Gang

Epigenetic Mechanisms of Cell Programming and Reprogramming
  • 出版商: Springer
  • 出版日期: 2024-08-21
  • 售價: $4,350
  • 貴賓價: 9.5 折 $4,133
  • 語言: 英文
  • 頁數: 55
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 9811974217
  • ISBN-13: 9789811974212

    • 海外代購書籍(需單獨結帳)

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商品描述

This book presents a major research program on epigenetic mechanisms of cell programming and reprogramming. The program was launched by the National Natural Science Foundation of China during the 11th Five-Year Plan period, which was started in October 2008 and concluded at the end of 2016. It first summarizes the epigenetic research plans and the current situation of epigenetic research in China and the international frontier. With the application of interdisciplinary research methods, the book discusses the development trends of epigenetic research, such as mechanisms of establishment and maintenance of epigenetic information and epigenetic regulation on reproduction and development. It also presents a variety of research achievements. For example, the discovery of new epigenetic regulators and chromatin remodulaters and their biological functions and mechanisms are highlighted. Several regulation mechanisms of cell differentiation and trans-differentiation are discussed, especially the discovery of the key factors to promote the trans-differentiation of somatic cells to hepatocytes. In addition, this book puts forward some key academic fields with increasing importance, such as biochemistry, cell biology, and clinical medicine. Given its scope, the book is of interest to researchers who work in cell biology, biochemistry, structural biology, bioinformatics, clinical medicine, and other related fields.

商品描述(中文翻譯)

本書介紹了一項關於細胞編程和重編程的表觀遺傳機制的重大研究計畫。該計畫由中國國家自然科學基金會於第十一個五年計畫期間啟動，該計畫始於2008年10月，並於2016年底結束。本書首先總結了中國的表觀遺傳研究計畫及其現狀，以及國際前沿的表觀遺傳研究。透過跨學科的研究方法，本書討論了表觀遺傳研究的發展趨勢，例如表觀遺傳信息的建立和維持機制，以及表觀遺傳對生殖和發展的調控。書中還展示了各種研究成果，例如新型表觀遺傳調控因子和染色質重塑因子的發現及其生物功能和機制。討論了幾種細胞分化和轉分化的調控機制，特別是促進體細胞轉分化為肝細胞的關鍵因素的發現。此外，本書提出了一些日益重要的關鍵學術領域，如生物化學、細胞生物學和臨床醫學。考慮到其範疇，本書對於從事細胞生物學、生物化學、結構生物學、生物資訊學、臨床醫學及其他相關領域的研究人員具有吸引力。

作者簡介

Professor Gang Pei was elected as an academician of the Chinese Academy of Sciences in 1999 and academician of the Third World Academy of Sciences in 2001. He is now the chairman of the Chinese Society of Cell Biology, vice chairman of the Chinese Medicine Globalization Alliance, chief editor of Cell Research, and editorial board member of various international academic journals. He also served as a member of the fourth and fifth expert advisory groups of the national key basic research and development plan (973 Plan), the convener of the first expert group of the national major scientific research plan of "stem cell research," and a member of the expert group of the national major infrastructure platform construction. He has long been engaged in cell signal transduction research and has published more than 100 research papers in international academic journals. He won the National Science Fund for Distinguished Young Scholars in 1996, the "Outstanding Young Scholar Award" of Qiushi Science and Technology Foundation in 1997, the Heliang Heli Science and Technology Progress Award in 1999, the second prize of the National Natural Science Award in 2002, the first prize of Shanghai Natural Science Award in 2006, the second prize of the National Natural Science Award in 2007, the Chen Jiageng Life Science Award in 2010, and the Tan Jiazhen Life Science Achievement Award in 2011.

作者簡介(中文翻譯)

裴剛教授於1999年當選為中國科學院院士，並於2001年當選為第三世界科學院院士。他目前擔任中國細胞生物學會會長、中國醫藥全球化聯盟副會長、《細胞研究》主編，以及多本國際學術期刊的編輯委員。他還曾擔任國家重點基礎研究發展計畫（973計畫）第四和第五屆專家諮詢小組成員、國家重大科學研究計畫「幹細胞研究」第一專家小組召集人，以及國家重大基礎設施平台建設專家小組成員。他長期從事細胞信號轉導研究，並在國際學術期刊上發表了超過100篇研究論文。他於1996年獲得國家優秀青年科學基金，1997年獲得求是科技基金「傑出青年學者獎」，1999年獲得何梁何利科學與技術進步獎，2002年獲得國家自然科學獎二等獎，2006年獲得上海自然科學獎一等獎，2007年獲得國家自然科學獎二等獎，2010年獲得陳嘉庚生命科學獎，2011年獲得譚家珍生命科學成就獎。

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