Skin Aging & Cancer: Ambient Uv-R Exposure
暫譯: 皮膚老化與癌症：環境紫外線輻射暴露
Dwivedi, Ashish, Agarwal, Neeraj, Ray, Lipika
- 出版商: Springer
- 出版日期: 2019-11-25
- 售價: $6,250
- 貴賓價: 9.5 折 $5,938
- 語言: 英文
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 9811325405
- ISBN-13: 9789811325403
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相關主題
商品描述
This book summarizes the potent effect of ultraviolet radiation (UVR) on the photoaging and cancer formation. Skin is the largest human organ which continually reconstructs itself to ensure its viability, integrity, and ability to provide protection for the body. This protection can be compromised by the aging of the skin which ultimately promotes skin inflammation, impaired wound repair, and increased risk of skin cancer. The book entails mechanistic insights into the UVR-induced immunomodulation and DNA damage in the skin to delineate the pathogenesis, and develop novel ways for prevention of photoaging of the skin cells. It also elucidates the potential of nanotechnology in the treatment of skin cancer. Further, it discusses the bioinformatics approaches to understand the molecular mechanism of photoaging and cancer formation.
商品描述(中文翻譯)
本書總結了紫外線輻射（UVR）對光老化和癌症形成的強大影響。皮膚是人體最大的器官，持續重建自身以確保其生存能力、完整性以及為身體提供保護的能力。這種保護可能會因皮膚老化而受到損害，最終促進皮膚發炎、傷口修復受損以及增加皮膚癌的風險。本書包含了有關UVR誘導的免疫調節和皮膚DNA損傷的機制性見解，以闡明發病機制，並開發預防皮膚細胞光老化的新方法。它還闡明了納米技術在皮膚癌治療中的潛力。此外，本書討論了生物資訊學方法，以理解光老化和癌症形成的分子機制。
作者簡介
Dr. Ashish Dwivedi is a Post-Doctoral Scientist in Skaggs School of Pharmacy & Pharmaceutical Sciences, Colorado University, Anschutz Medical Campus, USA. He has done his Doctoral Research from Photobiology Division, Indian Institute of Toxicology Research (IITR), Lucknow. His Doctorate research work was focused on phototoxicity assessment of different therapeutic drugs and environmental pollutants. He has eleven years of research experience in Photosciences and published numerous papers in reputed journals of Photochemistry & Photobiology, Toxicology, Biomaterials, Hazardous materials etc.
Dr. Neeraj Agarwal is working as a Scientist in NCI-designated University of Colorado Comprehensive Cancer Center, Aurora, CO, USA. Previously, he has completed his Ph.D. (2001 to 2007) from Photobiology, Division of Indian Institute of Toxicology Research (IITR), Lucknow. His work was focused on determining the phototoxic potential of commonly used therapeutic drugs and their mechanism of action. He has published seven research papers and presented his work at various conferences. He has received best poster award in 2002 for the work related to ciprofloxacin phototoxicity. In 2007, he joined Louisiana Health Sciences Center (LSUHSC), New Orleans, USA as a Postdoctoral Researcher and worked for five years towards understating the role of MTBP protein in osteosarcoma metastasis and also on identifying and characterizing the cancer stem cells in osteosarcoma. He has received Scientific Excellence Award and was invited to present his work in Cancer Center Retreat in 2010. Till now, he has published 18 research articles in reputed international journals with high impact factors, including Cancer Research, Oncogene, Cell Death and Differentiation, Clinical Cancer Research, and Photochemistry and Photobiology.
Dr. Lipika Ray is a Scientist in Pharmaceutics and Pharmacokinetics division, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow. She has expertise in the field of nanomedicine. Previously, she has done post-doctoral research as a DST-Young Scientist in Photobiology Division, Indian Institute of Toxicology Research (IITR), Lucknow. The project was mainly focused on phototoxicity assessment of bulk and nano-curcumin. Till now, she has fifteen years of research experience and published numerous papers in peer-reviewed journals such as Biomaterials, International Journal of Pharmaceutics, European Journal of Pharmaceutics and Biopharmaceutics, etc.
作者簡介(中文翻譯)
阿希什·德維迪博士是美國科羅拉多大學安舒茨醫學校的斯卡格斯藥學與藥物科學研究所的博士後科學家。他在印度毒理研究所（IITR）光生物學部完成了博士研究。他的博士研究工作專注於不同治療藥物和環境污染物的光毒性評估。他在光科學領域擁有十一年的研究經驗，並在光化學與光生物學、毒理學、生物材料、有害材料等知名期刊上發表了多篇論文。
尼拉吉·阿加瓦爾博士在美國科羅拉多大學綜合癌症中心（NCI指定）擔任科學家，位於科羅拉多州奧羅拉。之前，他於2001年至2007年在印度毒理研究所（IITR）光生物學部完成了博士學位。他的工作專注於確定常用治療藥物的光毒性潛力及其作用機制。他已發表七篇研究論文，並在各種會議上展示了他的工作。他在2002年因與環丙沙星光毒性相關的工作獲得最佳海報獎。2007年，他加入美國路易斯安那州健康科學中心（LSUHSC）作為博士後研究員，並在五年內研究MTBP蛋白在骨肉瘤轉移中的角色，以及識別和表徵骨肉瘤中的癌幹細胞。他獲得了科學卓越獎，並於2010年受邀在癌症中心退修會上展示他的工作。至今，他已在包括《癌症研究》、《腫瘤基因》、《細胞死亡與分化》、《臨床癌症研究》和《光化學與光生物學》等高影響因子的國際知名期刊上發表了18篇研究文章。
莉皮卡·雷博士是位於印度盧克瑙的CSIR中央藥物研究所（CSIR-CDRI）藥物學與藥物動力學部的科學家。她在納米醫學領域擁有專業知識。之前，她在印度毒理研究所（IITR）光生物學部作為DST青年科學家進行博士後研究。該項目主要專注於大宗和納米薑黃素的光毒性評估。至今，她擁有十五年的研究經驗，並在《生物材料》、《國際藥物學期刊》、《歐洲藥物學與生物藥物學期刊》等同行評審期刊上發表了多篇論文。
