Essentials of Single-Cell Analysis: Concepts, Applications and Future Prospects (Series in BioEngineering)
暫譯: 單細胞分析的基本要素:概念、應用與未來展望(生物工程系列)

  • 出版商: Springer
  • 出版日期: 2018-03-30
  • 售價: $4,600
  • 貴賓價: 9.5$4,370
  • 語言: 英文
  • 頁數: 424
  • 裝訂: Paperback
  • ISBN: 3662569809
  • ISBN-13: 9783662569801
  • 海外代購書籍(需單獨結帳)

商品描述

This book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations.

This book is enjoyable reading material while at the same time providing essential information to scientists in academia and professionals in industry working on different aspects of single-cell analysis. 

Dr. Fan-Gang Tseng is a Distinguished Professor of Engineering and System Science at the National Tsing Hua University, Taiwan.

Dr. Tuhin Subhra Santra is a Research Associate at the California Nano Systems Institute, University of California at Los Angeles, USA.

商品描述(中文翻譯)

這本書提供了單細胞分離、隔離、注射、裂解及動態分析的概述,並利用不同的微型裝置研究其異質性。作為單細胞分析的重要部分,書中詳細描述了包括電穿孔(electroporation)、微注射(microinjection)、光學捕捉(optical trapping)、光穿孔(optoportation)、快速電動力學圖案化(rapid electrokinetic patterning)和光電捕捉器(optoelectronic tweezers)等不同技術。它介紹了不同的流體系統(例如,連續微/納米流體裝置、微流體細胞計數技術)及其與傳感器技術、光學和流體動力學拉伸器等的整合,並展示了單細胞分析在系統生物學、蛋白質組學、基因組學、表觀基因組學、癌症轉錄組學、代謝組學、生物醫學和藥物傳遞系統中的應用。書中還討論了單細胞分析的未來挑戰,包括其優勢和限制。

這本書不僅是愉快的閱讀材料,同時也為學術界的科學家和業界專業人士提供了有關單細胞分析不同方面的必要資訊。

曾繁剛博士是國立清華大學工程與系統科學系的特聘教授。

Tuhin Subhra Santra博士是美國加州大學洛杉磯分校加州奈米系統研究所的研究助理。