Perioperative Inflammation as Triggering Origin of Metastasis Development
暫譯: 圍手術期炎症作為轉移發展的觸發來源
Retsky, Michael W., Demicheli, Romano
- 出版商: Springer
- 出版日期: 2018-08-12
- 售價: $6,930
- 貴賓價: 9.5 折 $6,584
- 語言: 英文
- 頁數: 236
- 裝訂: Quality Paper - also called trade paper
- ISBN: 3319862898
- ISBN-13: 9783319862897
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相關主題
商品描述
The book will explain previously unconnected clinical data such as why mammography works better for women age 50-59 than it does for women age 40-49, why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes, and it may also explain the racial disparity in outcome. In particular, it points to the perioperative period when systemic inflammation persists for a week or so. This can lead to a variety of mechanisms whereby single cancer cells (perhaps from the marrow) begin division and angiogenesis of dormant avascular micrometastases occurs leading to early relapses.
With chapters presented from distinguished scientists and physicians in a variety of specialties that relate to and border the effects we present, this volume can be used as a reference for practicing physicians and as a jumping-off point for researchers to explore new therapeutic opportunities.
商品描述(中文翻譯)
這本書將解釋先前未連結的臨床數據,例如為什麼乳房攝影對於50至59歲的女性效果較40至49歲的女性更佳,為什麼輔助化療對於淋巴結陽性的絕經前患者效果最佳,並且可能解釋結果中的種族差異。特別是,它指出在全身性炎症持續約一週的圍手術期。這可能導致多種機制,使得單一癌細胞(可能來自骨髓)開始分裂,並且潛伏的無血管微轉移的血管生成發生,導致早期復發。
本書的章節由各個專業領域的傑出科學家和醫生撰寫,這些領域與我們所呈現的影響相關或相互交錯,這本書可以作為執業醫生的參考資料,也可以作為研究人員探索新治療機會的起點。
作者簡介
Romano Demicheli, MD, PhD, is Senior Researcher, Istituto Nazionale Tumori di Milano
作者簡介(中文翻譯)
邁克爾·瑞茲基 (Michael Retsky), 博士 是哈佛大學 T.H. 陳公共衛生學院的研究助理及倫敦大學學院的榮譽教員。
羅馬諾·德米凱利 (Romano Demicheli), 醫學博士、博士 是米蘭國家腫瘤研究所的高級研究員。