Asbestos and Mesothelioma
暫譯: 石棉與間皮瘤

Testa, Joseph R.

Asbestos and Mesothelioma
  • 出版商: Springer
  • 出版日期: 2018-08-08
  • 售價: $5,760
  • 貴賓價: 9.5 折 $5,472
  • 語言: 英文
  • 頁數: 407
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3319851837
  • ISBN-13: 9783319851839

    • 海外代購書籍(需單獨結帳)

商品描述

This volume is comprised of a multidisciplinary assessment of the interplay between asbestos and cancer as well as new research about the biology and treatment of malignant mesothelioma. Chapters on the various types of asbestos and other mineral fibers, epidemiology, history and future of asbestos-related diseases are included. Other reviews present new information about the role of asbestos-related inflammation and genetic factors, including the role of inherited mutations of BAP1, in mesothelioma causation, as well as recent research about gene signatures, cell signaling, and epigenetic mechanisms in asbestos-related diseases. Other chapters provide updates of novel disease biomarkers and prevention, mechanistic lesson from genetically engineered mouse and 3-D models of mesothelioma tumorigenesis and therapeutic resistance. Also included are up-to-date reviews of surgical, molecularly targeted chemotherapeutic, and immunotherapeutic approaches for mesothelioma as well as an overview of legal issues.

商品描述(中文翻譯)

本卷包含了對石棉與癌症之間相互作用的多學科評估，以及有關惡性間皮瘤的生物學和治療的新研究。章節涵蓋了各種石棉及其他礦物纖維的類型、流行病學、石棉相關疾病的歷史與未來。其他評論則提供了有關石棉相關炎症和遺傳因素的新資訊，包括遺傳突變 BAP1 在間皮瘤致病中的角色，以及最近有關基因特徵、細胞信號傳遞和表觀遺傳機制在石棉相關疾病中的研究。其他章節提供了新型疾病生物標記和預防的最新資訊，從基因工程小鼠和間皮瘤腫瘤生成及治療抵抗的三維模型中獲得的機制性教訓。此外，還包括了對於間皮瘤的外科、分子靶向化療和免疫療法方法的最新評論，以及法律問題的概述。

作者簡介

Joseph R. Testa, PhD, FACMG is Senior Member/Professor, Carol and Kenneth E. Weg Chair in Human Genetics, Chief of Laboratory Genetics, and Co-Leader of the Cancer Biology Program at Fox Chase Cancer Center, Philadelphia, PA. His research interests focus on mesothelioma pathogenesis and AKT-related oncogenesis. He has published numerous papers and reviews, and serves on the editorial boards of several journals, including as Senior Editor for Cancer Research. He has received multiple science awards, including the J. Christopher Wagner Medal from the International Mesothelioma Interest Group and the Pioneer Research Award from the Mesothelioma Applied Research Foundation. He is also a Fellow of the American Association for the Advancement of Science.

作者簡介(中文翻譯)

約瑟夫·R·泰斯塔（Joseph R. Testa），博士，FACMG，是賓夕法尼亞州費城福克斯查斯癌症中心（Fox Chase Cancer Center）的人類遺傳學卡羅爾與肯尼斯·E·韋格（Carol and Kenneth E. Weg）講座教授、高級成員、實驗室遺傳學主任及癌症生物學計畫的共同領導者。他的研究興趣集中在間皮瘤的發病機制及AKT相關的腫瘤生成上。他發表了多篇論文和評論，並擔任多本期刊的編輯委員會成員，包括擔任《癌症研究》（Cancer Research）的高級編輯。他獲得了多項科學獎項，包括國際間皮瘤關注小組頒發的J·克里斯托弗·瓦格納獎章（J. Christopher Wagner Medal）及間皮瘤應用研究基金會的先驅研究獎（Pioneer Research Award）。他也是美國科學促進會（American Association for the Advancement of Science）的會士。

類似商品

最後瀏覽商品 (9)