Catharanthus Roseus: Current Research and Future Prospects
暫譯: 長春花：當前研究與未來展望

本書研究了重要藥用植物 Catharanthus roseus (L.) G. Don，通常稱為長春花，所產生的吲哚生物鹼。抗癌生物鹼，如長春新碱（vinblastine）和長春花鹼（vincristine），主要存在於 C. roseus 的葉子中，通過阻礙細胞分裂過程中有絲分裂器的形成來抑制癌細胞的生長。此外，長春新碱有助於提高兒童白血病的存活機會，而長春花鹼則用於治療霍奇金病。為了大規模生產這些生物鹼，已經進行了大量努力，通過植物細胞培養來實現。考慮到全球對商業用途的需求，本書探討了如何最大化從 C. roseus 中生產抗癌生物鹼。本參考書將對研究生、教師、民族植物學家、藥理學家以及對這種極其重要的抗癌藥用植物有濃厚興趣的草藥種植者有所幫助。

Dr. M. Naeem is a Postdoctoral Fellow (Young Scientist) in the Department of Botany at Aligarh Muslim University, India. For more than a decade, he has devoted his research to improving the yield and quality of commercially important medicinal and aromatic plants (MAPs). His research focuses on escalating the production of MAPs and their active principles using a novel and safe technique involving radiation-processed polysaccharides as well as the application of potent PGRs. To date, he has successfully run three major research projects as Principal Investigator, two of which were sanctioned by the Department of Science & Technology, New Delhi. He also completed another intriguing research project on Catharanthus roseus awarded by CSTUP, Lucknow. Dr. Naeem has published more than 75 research papers in reputable national and international journals as well as six books. He has also participated in various national and international conferences and acquired life memberships to various scientific bodies in India and abroad. Based on his research contributions, Dr. Naeem has been awarded a Research Associateship from the Council of Scientific & Industrial Research, New Delhi; a Young Scientist Award (2011) from the State Government of Uttar Pradesh; a Fast Track-Young Scientist Award from the Department of Science & Technology, India; a Young Scientist of the Year Award (2015) from the Scientific and Environmental Research Institute, Kolkata; and a Rashtriya Gaurav Award (2016) from the International Friendship Society, New Delhi.

Tariq Aftab received his Ph.D. in the Department of Botany at Aligarh Muslim University, India, and is currently an Assistant Professor there. He is the recipient of a prestigious Leibniz-DAAD fellowship from Germany, a Raman Fellowship from the Government of India, and Young Scientist Awards from the State Government of Uttar Pradesh and Government of India. He is also a member of various scientific associations from India and abroad. He has worked as Visiting Scientist at IPK, Gaterleben, Germany and in the Department of Plant Biology, Michigan State University, USA. He has published research articles in several peer-reviewed national and international journals and is the lead editor of the book Artemisia annua: Pharmacology and Biotechnology. His research interests include physiological, proteomic, and molecular studies on medicinal and aromatic plants.

Prof. M. Masroor A. Khan is a professor in the Department of Botany at Aligarh Muslim University, India. After completing his Ph.D., he worked as a postdoctoral fellow at Ohio State University, USA (1987-88). Then he worked as Pool Scientist for the Council of Scientific and Industrial Research and a Research Associate for CSIR and the University Grants Commission before he joined AMU as an Assistant Professor. In his 30 years of teaching experience at the university level, he has guided 8 Ph.D., 2 M.Phil., and 27 M.Sc. students. For the convenience of his students, he has also developed study materials and launched more than 100 class notes and PowerPoint presentations on his website. Prof. Khan has run six research projects sponsored by national and international funding agencies and has published more than one hundred research papers in reputable journals and books. In his research, Prof. Khan is working to promote the productivity and active ingredients of medicinal and aromatic plants using different strategies such as the application of mineral nutrition, PGRs, and nanoparticles. Prof. Khan has contributed greatly towards the establishment of Radiation-Processed Polysaccharides (RPPs) as plant growth promoters. In collaboration with the Bhabha Atomic Research Centre, Mumbai, he is researching the appropriate doses of RPPs that would help farmers increase the productivity of medicinal and aromatic plants and their active constituents. Another field of his research is nanoparticles, some of which he has found can enhance the essential oil production of some aromatic plants. He has also filed a patent in this regard.

Dr. M. Naeem 是印度阿里格爾穆斯林大學植物學系的博士後研究員（青年科學家）。十多年來，他專注於提高商業上重要的藥用和芳香植物（MAPs）的產量和品質。他的研究重點是利用一種新穎且安全的技術，通過輻射處理的多醣類以及強效植物生長調節劑（PGRs）的應用，來提升MAPs及其活性成分的產量。迄今為止，他作為主要研究者成功執行了三個主要研究項目，其中兩個獲得了新德里科學與技術部的批准。他還完成了一個由盧克瑙CSTUP頒發的有趣研究項目，研究對象為Catharanthus roseus。Dr. Naeem在國內外知名期刊上發表了超過75篇研究論文，並出版了六本書籍。他還參加了各種國內外會議，並獲得了印度及國外多個科學機構的終身會員資格。基於他的研究貢獻，Dr. Naeem獲得了新德里科學與工業研究委員會的研究助理獎、烏塔爾邦州政府的青年科學家獎（2011）、印度科學與技術部的快速通道青年科學家獎、加爾各答科學與環境研究所的年度青年科學家獎（2015），以及新德里國際友誼協會的國家榮耀獎（2016）。

Tariq Aftab 在印度阿里格爾穆斯林大學植物學系獲得博士學位，目前擔任該校的助理教授。他是德國著名的萊布尼茨-DAAD獎學金獲得者、印度政府的拉曼獎學金獲得者，以及烏塔爾邦州政府和印度政府的青年科學家獎獲得者。他還是來自印度及國外的多個科學協會的成員。他曾在德國Gaterleben的IPK擔任訪問科學家，並在美國密西根州立大學的植物生物學系工作。他在多個同行評審的國內外期刊上發表了研究文章，並擔任書籍《Artemisia annua: Pharmacology and Biotechnology》的主編。他的研究興趣包括藥用和芳香植物的生理學、蛋白質組學和分子研究。

Prof. M. Masroor A. Khan 是印度阿里格爾穆斯林大學植物學系的教授。在完成博士學位後，他在美國俄亥俄州立大學擔任博士後研究員（1987-88）。隨後，他擔任科學與工業研究委員會的池科學家及CSIR和大學補助委員會的研究助理，然後加入AMU擔任助理教授。在他30年的大學教學經驗中，他指導了8名博士生、2名碩士生和27名碩士學生。為了方便學生，他還開發了學習材料，並在其網站上發布了超過100份課堂筆記和PowerPoint簡報。Prof. Khan執行了六個由國內外資助機構贊助的研究項目，並在知名期刊和書籍上發表了超過一百篇研究論文。在他的研究中，Prof. Khan致力於通過應用礦物營養、PGRs和納米顆粒等不同策略來促進藥用和芳香植物的生產力和活性成分。Prof. Khan對於建立輻射處理多醣類（RPPs）作為植物生長促進劑做出了重大貢獻。他與孟買的巴巴原子研究中心合作，研究適當劑量的RPPs，以幫助農民提高藥用和芳香植物及其活性成分的產量。他的另一個研究領域是納米顆粒，其中一些他發現可以增強某些芳香植物的精油產量。他還就此申請了專利。