Next Generation Antibody Drug Conjugates (Adcs) and Immunotoxins
暫譯: 下一代抗體藥物偶聯物(ADCs)與免疫毒素

Grawunder, Ulf, Barth, Stefan

  • 出版商: Springer
  • 出版日期: 2018-07-18
  • 售價: $6,930
  • 貴賓價: 9.5$6,584
  • 語言: 英文
  • 頁數: 181
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3319836099
  • ISBN-13: 9783319836096
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities.

The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.


商品描述(中文翻譯)

本書描述了抗體藥物偶聯物和免疫毒素的最新發展,為其臨床應用鋪平道路。從當前最先進技術中獲得的經驗教訓被用來進一步改善我們對其作用機制和非靶向活性的理解。

本書向科學家介紹了必須妥善處理的所有前提條件,包括正確靶標的識別、靶向結合抗體的特定特徵、毒性載荷的正確選擇、由結合引起的內化,以及下一代偶聯和連接技術。這些基於知識的革命性新藥原則將成為未來護理標準的基石,並將促進應用的重大進展,以及改善生活質量和患者生存率。本書將吸引在免疫學、藥理學和腫瘤學領域工作的生技公司和研究人員。

最後瀏覽商品 (20)