Environmental Factors in the Pathogenesis of Cardiovascular Diseases
Djuric, Dragan M., Agrawal, Devendra K.
- 出版商: Springer
- 出版日期: 2024-08-02
- 售價: $10,250
- 貴賓價: 9.5 折 $9,738
- 語言: 英文
- 頁數: 988
- 裝訂: Hardcover - also called cloth, retail trade, or trade
- ISBN: 3031628055
- ISBN-13: 9783031628054
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商品描述
Environmental conditions and processes are one of the major pillars on which the human well-being rests. It is the core responsibility of the society to preserve and enhance better conditions for the human well-being. Indeed, there are several evolving unmet needs in public health. Emerging and re-emerging infectious diseases and a surge in the incidence of non-communicable diseases, including cardiovascular diseases (CAD), chronic respiratory diseases, and metabolic diseases have been impediments to sustainable well-being.
Many factors are critical in the global surge in the rate and incidence of cardiovascular diseases. These include the shift from acute to chronic conditions, the shift from single risk factor vs. multiple influences, aging population, global health disparities, exposure to lower harmful influences over a longer period, etc. However, the epigenetic factors due to unhealthy environment play a most significant role in the underlying pathogenesis of cardiovascular diseases. Unfortunately, this has been ignored for a long time and realized lately to expand and disseminate knowledge to general population, expand research activities to investigate the cellular and molecular mechanisms, and develop better preventive and treatment strategies.
The most significant environmental impoverishment in the pathogenesis of cardiovascular diseases include different genetical, chemical, physical, and biological influences, but not limited to, socio-economic status and lack of nutrients, nutritional aspects including habits, diets and additives, inhaled and ingested pollutants, exhaust gas and gasoline products, tobacco smoke, water pollution, alcohol consumption, soil and mineral pollution, solvents, pesticides, microplastics, non-critical usage of drugs, climate change, extreme atmospheric conditions, extremes in noise and temperature, electromagnetic influences, microwaves and radiation, outdoor light pollution, mental stressors, lack of or over exercise, microbiota and microbiological agents like SARS CoV-2 virus, etc.
商品描述(中文翻譯)
環境條件和過程是人類福祉的主要支柱之一。保護和改善人類福祉的條件是社會的核心責任。事實上,公共衛生領域存在著幾個不斷發展的未滿足需求。新興和再次出現的傳染病以及非傳染性疾病的發病率激增,包括心血管疾病(CAD)、慢性呼吸道疾病和代謝性疾病,已成為可持續福祉的障礙。
許多因素對全球心血管疾病的發病率和發病率激增至關重要。這些因素包括從急性病變轉變為慢性病變、單一風險因素與多重影響之間的轉變、人口老化、全球衛生差距、長期暴露於較低有害影響、等等。然而,由於不健康環境而引起的表觀遺傳因素在心血管疾病的潛在發病機制中起著最重要的作用。不幸的是,這個問題長期以來一直被忽視,直到最近才意識到需要向廣大人口擴展和傳播知識,擴大研究活動以研究細胞和分子機制,並制定更好的預防和治療策略。
在心血管疾病發病機制中,最重要的環境貧困因素包括不同的遺傳、化學、物理和生物影響,但不限於社會經濟地位和營養不良、營養方面包括習慣、飲食和添加劑、吸入和攝入的污染物、廢氣和汽油產品、煙草煙霧、水污染、酒精消耗、土壤和礦物污染、溶劑、農藥、微塑料、非關鍵性藥物使用、氣候變化、極端大氣條件、極端噪音和溫度、電磁影響、微波和輻射、戶外光污染、心理壓力、缺乏或過度運動、微生物群落和SARS CoV-2病毒等微生物因子。
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