Primary Adrenal Malignancies

Tiberio, Guido A. M.

  • 出版商: Springer
  • 出版日期: 2024-11-14
  • 售價: $2,320
  • 貴賓價: 9.5$2,204
  • 語言: 英文
  • 頁數: 176
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3031623002
  • ISBN-13: 9783031623004
  • 尚未上市,無法訂購

商品描述

Dissemination of knowledge is the best and only strategy capable of improving clinical management in rare and ultra-rare malignancies, including primary adrenal malignancies. It is preliminary to any further healthcare policy such as, for example, the centralization of cases in referral institutions.

Adrenal primary malignancies are probably the rarest among rare pathologies. This epidemiological consideration is at the origin of a vicious circle: the lack of preoperative diagnosis leads to inappropriate surgical procedures and to inadequate follow-up and systemic therapy strategies. Furthermore, when malignancy is recognized, the relative role of systemic, surgical, or other local ablative techniques is often misinterpreted. All this produces a negative impact on survival, also in patients who could have been cured with a correct therapeutic strategy.

This open access book provides a user-friendly exploration of these rare conditions, using a transversal approach common in modern precision medicine. The text covers various clinical aspects, including epidemiology, genetics, molecular medicine, imaging, and surgery. Guidelines for managing syndromic situations are provided. The book thoroughly addresses all the different surgical issues and emphasizes the importance of pathology in assessing prognosis. The pivotal role of medical oncologists in managing these patients is explored, along with alternative treatments such as nuclear medicine and radiotherapy. Finally, the book highlights the latest preclinical research and its implications for translational medicine.

商品描述(中文翻譯)

知識的傳播是改善罕見及超罕見惡性腫瘤(包括原發性腎上腺惡性腫瘤)臨床管理的最佳且唯一策略。這是任何進一步醫療政策的前提,例如將病例集中於轉診機構。

原發性腎上腺惡性腫瘤可能是所有罕見病症中最罕見的。這一流行病學考量導致了一個惡性循環:術前診斷的缺乏導致不當的手術程序以及不充分的隨訪和系統治療策略。此外,當惡性腫瘤被識別時,系統性、外科或其他局部消融技術的相對作用常常被誤解。所有這些都對生存率產生了負面影響,即使在那些本可以通過正確治療策略治癒的患者中也是如此。

這本開放存取的書籍以使用者友好的方式探索這些罕見病症,採用現代精準醫學中常見的橫向方法。文本涵蓋了各種臨床方面,包括流行病學、遺傳學、分子醫學、影像學和外科手術。提供了管理綜合症情況的指導方針。書中徹底探討了所有不同的外科問題,並強調病理學在評估預後中的重要性。醫學腫瘤學家在管理這些患者中的關鍵角色也得到了探討,並介紹了核醫學和放射治療等替代療法。最後,書中突顯了最新的臨床前研究及其對轉化醫學的影響。

作者簡介

Professor Tiberio started his academic career as an Assistant Professor of General Surgery at the University of Brescia in 1995. From 1997 to 1998 he worked as Assistant étranger en Chirurgie Générale et Digestive at the Université Luis Pasteur in Strasbourg, France. In 2000 he was appointed Associate Professor of General Surgery at the University of Brescia. Full Professor of General Surgery from 2006, he served at the Campus Bio-Medico University in Rome and, from 2012, at the University of Brescia. His surgical activity is mainly carried out as a Senior Consultant at ASST Spedali Civili di Brescia, a regional tertiary university hospital. His areas of main interest include digestive (with particular emphasis on gastric neoplasms), hepatic, pancreatic and adrenal surgery, emergency surgery and surgery of peritoneal surface malignancies. Prof. Tiberio's scientific activity addresses both clinical research and basic science with translational interest.

作者簡介(中文翻譯)

提貝里奧教授於1995年開始他的學術生涯,擔任布雷西亞大學的普通外科助理教授。1997年至1998年間,他在法國斯特拉斯堡的路易斯·巴斯德大學擔任普通及消化外科的外國助理。2000年,他被任命為布雷西亞大學的普通外科副教授。自2006年起擔任普通外科的正教授,他在羅馬的生物醫學大學任職,並自2012年起回到布雷西亞大學。他的外科活動主要在布雷西亞的ASST Spedali Civili,這是一所區域性三級大學醫院,擔任高級顧問。他的主要研究領域包括消化外科(特別強調胃腫瘤)、肝臟、胰臟和腎上腺外科、急診外科以及腹膜表面惡性腫瘤的外科手術。提貝里奧教授的科學活動涵蓋臨床研究和基礎科學,並具有轉譯研究的興趣。