Autism Spectrum Disorder: Understanding the Female Phenotype

Mazzone, Luigi, Siracusano, Martina, Pelphrey, Kevin A.

Autism Spectrum Disorder: Understanding the Female Phenotype
  • 出版商: Springer
  • 出版日期: 2024-08-20
  • 售價: $4,960
  • 貴賓價: 9.5 折 $4,712
  • 語言: 英文
  • 頁數: 198
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 3031620712
  • ISBN-13: 9783031620713

    • 海外代購書籍(需單獨結帳)

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商品描述

This book provides a comprehensive overview of the current state of knowledge on autism in females, in order to help understand and clarify gender implications in the autistic female phenotype. Despite the reported higher risk of developing autism in males than in females, few studies have investigated the gender differences at the clinical and neurobiological level. Possible genetic protective factors, as well as differing neurobiological brain trajectories, could be responsible for the male/female discrepancy in prevalence rates (4:1). Moreover, a different clinical phenotype regarding the onset of symptoms, behavioral features and social motivation often skews diagnosis in women. Specifically, the phenomenon of camouflaging or hiding symptoms in high functioning females, due to behavioral coping strategies, contributes to incorrect or delayed diagnosis.

In addition to addressing an important gap in the literature, this book provides concrete and specific diagnostic recommendations and intervention strategies. In addition, a dedicated chapter presents clinical case reports and shares the personal experiences of autistic women. Given its scope, the book will appeal to clinicians and practitioners, as well as researchers and students in the fields of child and adult psychiatry, psychology and neuropsychiatry.

商品描述(中文翻譯)

本書提供了對女性自閉症的現有知識的全面概述，以幫助理解和澄清自閉症女性表型中的性別影響。儘管男性發展自閉症的風險報告比女性高，但很少有研究在臨床和神經生物學層面上探討性別差異。可能的遺傳保護因子以及不同的神經生物學腦部發展軌跡可能是男性/女性患病率差異（4:1）的原因。此外，關於症狀發作的開始、行為特徵和社交動機的不同臨床表型常常使女性的診斷出現偏差。具體而言，高功能女性因行為應對策略而掩飾或隱藏症狀的現象，導致診斷不正確或延遲。

除了填補文獻中的重要空白，本書還提供具體和具體的診斷建議和干預策略。此外，一個專門的章節介紹了臨床案例報告，並分享了自閉症女性的個人經歷。鑑於其範圍，本書將吸引兒童和成人精神病學、心理學和神經精神病學領域的臨床醫生、從業人員、研究人員和學生。

作者簡介

Luigi Mazzone, MD, PhD, Full Professor in Child Neuropsychiatry. He is currently the Chief of the Child and Adolescent Psychiatry Division and the Director of the Medical Residency School of the University of Rome Tor Vergata, Italy. Several are the international fellowships he experienced during his academic career: the National Institute of Mental Health (NIMH), Bethesda, MD, USA; the Pediatric Brain Imaging Laboratory at Columbia University, NY, USA. Luigi Mazzone has focused his research and clinical activity both on the study of neurobiological substrates and on the characterization of the clinical phenotype of neurodevelopmental disorders such as autism spectrum disorder and ADHD. To date, he has published more than 150 articles in peer reviewed international scientific journals. He has already published with Springer the volume "Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder" in 2016.

Martina Siracusano, MD, PhD, is currently a Clinical Researcher at the Department of Biomedicine and Prevention of the University of Rome Tor Vergata (Italy) and carries out her main clinical activity in the Child and Adolescent Psychiatry Division of the Rome Tor Vergata University Hospital. Her primary research and clinical topic of interest is on autism spectrum disorder (early diagnosis, identification of biomarkers, medical comorbidities, genetic syndromes). She is actually involved in several research projects granted by the Italian National Health System focused on these themes.

Kevin Pelphrey, a neuroscientist and expert on child brain development, is the Harrison-Wood Professor of Neurology at the University of Virginia, USA. As a cognitive neuroscientist, his research investigates the brain basis of autism and related neurodevelopmental disorders. His multidisciplinary team seeks to understand the causes of autism to help get the right treatment to the right individual at the right time. Kevin is the Principal Investigator of the NIH Autism Center for Excellence--Neurogenetics of Females with Autism Network. His contributions to science have been recognized by receipt of a NIH Scientist Career Development Award, the John Merck Scholars Award, the Microsoft Corporation's Breakthrough Award, and the American Psychological Association's Boyd McCandless Award for distinguished early career theoretical contributions to Developmental Psychology. As a father and advocate, he serves by appointment of the United States Secretary of Health and Human Services as a member of the Federal Interagency Autism Coordinating Committee, USA.

作者簡介(中文翻譯)

Luigi Mazzone，醫學博士、哲學博士，是義大利羅馬托爾維爾加塔大學兒童神經精神病學的全職教授。他目前擔任兒童與青少年精神病學部門主任，以及羅馬托爾維爾加塔大學醫學住院醫師學校的主任。在他的學術生涯中，他曾經有過多次國際研究經歷，包括美國國家精神健康研究所（NIMH）和哥倫比亞大學兒童腦影像實驗室。Luigi Mazzone的研究和臨床活動主要集中在神經生物學基礎的研究和自閉症譜系障礙和注意力缺陷過動症等神經發育障礙的臨床表型特徵的描述上。迄今為止，他已在同行評審的國際科學期刊上發表了150多篇文章。他已於2016年與Springer出版了《自閉症譜系障礙中的精神病症狀和共病》一書。

Martina Siracusano，醫學博士、哲學博士，目前是義大利羅馬托爾維爾加塔大學生物醫學與預防學系的臨床研究員，並在羅馬托爾維爾加塔大學醫院的兒童與青少年精神病學部門從事主要臨床工作。她主要的研究和臨床興趣集中在自閉症譜系障礙（早期診斷、生物標記的鑑定、醫學共病、遺傳綜合症）上。她目前參與了幾個由義大利國家衛生系統資助的研究項目，重點是這些主題。

Kevin Pelphrey，神經科學家和兒童腦發育專家，是美國維吉尼亞大學的哈里森-伍德神經學教授。作為一位認知神經科學家，他的研究探討自閉症和相關神經發育障礙的大腦基礎。他的跨學科團隊致力於了解自閉症的原因，以便在適當的時間給予適當的治療。Kevin是美國國家衛生研究院自閉症卓越中心的首席研究員，該中心專注於女性自閉症的神經遺傳學。他的科學貢獻獲得了美國國家衛生研究院科學家職業發展獎、約翰·默克學者獎、微軟公司突破獎和美國心理學協會發展心理學早期理論貢獻博伊德·麥坎德萊斯獎的認可。作為一位父親和倡導者，他被美國衛生與公共服務部任命為聯邦政府自閉症協調委員會的成員。

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