Physical Virology: From the State-Of-The-Art Research to the Future of Applied Virology
Comas-Garcia, Mauricio, Rosales-Mendoza, Sergio
- 出版商: Springer
- 出版日期: 2024-10-03
- 售價: $7,030
- 貴賓價: 9.5 折 $6,679
- 語言: 英文
- 頁數: 340
- 裝訂: Quality Paper - also called trade paper
- ISBN: 3031368177
- ISBN-13: 9783031368172
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相關主題
商品描述
This book highlights key findings generated during the past years from the main disciplines that constitute Physical Virology, from theoretical physics and simulations to material sciences and vaccines development to structural biology. Each chapter is written by world-class scientists from these areas and is a comprehensive review of where this field stands, as well as the future of Physical Virology. The diversity in the formal training of these scientists results in solving common problems using very distinct approaches, which can produce surprising findings. The multi- and interdisciplinary nature of this field has created a remarkable community that aims at understanding how viruses work and how they can be used in material sciences, chemistry, and biomedicine. Furthermore, the development of Physical Virology has resulted in technological advances that have shaped other fields; for example, it would be impossible to think about the development of Cryo-EM to solve the structure of complex viruses with atomic resolution without the contribution of scientists that created the field of Physical Virology. In the past decade, there has been a great success in the generation of viral systems that can encapsulate drugs, non-viral genetic material, or nanoparticles, as well as in the chemical and genetical modification of virions. Without any doubt in the immediate future, some of these technologies will jump from the bench to the market, creating a revolution in translational and biomedical sciences. The book provides key perspectives for the field, derived from expert s opinions.
商品描述(中文翻譯)
本書突顯了過去幾年在構成物理病毒學的主要學科中產生的關鍵發現,這些學科包括理論物理學與模擬、材料科學、疫苗開發以及結構生物學。每一章均由來自這些領域的世界級科學家撰寫,全面回顧了該領域的現狀以及物理病毒學的未來。這些科學家在正式訓練上的多樣性使得他們能夠以非常不同的方法解決共同的問題,從而產生驚人的發現。該領域的多學科和跨學科特性創造了一個卓越的社群,旨在理解病毒的運作方式以及如何在材料科學、化學和生物醫學中加以利用。此外,物理病毒學的發展促成了技術上的進步,這些進步影響了其他領域;例如,若沒有創建物理病毒學領域的科學家的貢獻,無法想像如何發展出冷凍電子顯微鏡(Cryo-EM)以原子解析度解決複雜病毒的結構。在過去十年中,成功生成了能夠包裹藥物、非病毒遺傳物質或納米顆粒的病毒系統,以及對病毒顆粒的化學和遺傳修飾。毫無疑問,在不久的將來,這些技術中的一些將從實驗室轉向市場,為轉化醫學和生物醫學科學帶來革命。本書提供了該領域的關鍵觀點,源自專家的意見。
作者簡介
Dr. Sergio Rosales-Mendoza is a Professor of Biotechnology at the University of San Luis Potosi, Mexico. He holds a Ph.D. in Molecular Biology, and his research interests include developing innovative vaccines by applying rational antigen design approaches and using innovative expression hosts and advanced antigen delivery vehicles. Dr. Rosales-Mendoza has published over 150scientific articles in peer-reviewed journals (H index: 32) and edited/written four books. In addition, he has trained several Ph.D. and postdoctoral fellows. Viral diseases had been a main target in Dr. Rosales´ research activity, with an interest in developing attractive vaccine prototypes against HIV, CHIKV, ZIKV, and SARS-CoV-2.
作者簡介(中文翻譯)
毛里西奧·科馬斯-加西亞博士是墨西哥聖路易斯波托西大學的生物學教授。他擁有加州大學洛杉磯分校的物理化學博士學位。他的研究興趣包括病毒如何重塑細胞,以及控制RNA病毒組裝和基因組包裝的物理互動。科馬斯-加西亞博士在同行評審的期刊上發表了超過20篇科學文章,並共同編輯了兩本書籍。他的研究活動專注於病毒如茲卡病毒(Zika)、基孔肯雅病毒(Chikungunya)和SARS-CoV-2的組裝、基因組包裝和病毒樣顆粒的生成。
塞爾吉奧·羅薩萊斯-門多薩博士是墨西哥聖路易斯波托西大學的生物技術教授。他擁有分子生物學的博士學位,研究興趣包括通過應用理性抗原設計方法和使用創新的表達宿主及先進的抗原遞送載體來開發創新疫苗。羅薩萊斯-門多薩博士在同行評審的期刊上發表了超過150篇科學文章(H指數:32),並編輯/撰寫了四本書。此外,他還培訓了多位博士及博士後研究員。病毒性疾病一直是羅薩萊斯博士研究活動的主要目標,他對開發針對HIV、基孔肯雅病毒、茲卡病毒和SARS-CoV-2的有吸引力的疫苗原型充滿興趣。