Heterocycles from Carbenes and Nitrenes: Methods, Reactions and Synthetic Applications

Doyle, Michael P., Xu, Xinfang

  • 出版商: Springer
  • 出版日期: 2024-08-11
  • 售價: $10,250
  • 貴賓價: 9.5$9,738
  • 語言: 英文
  • 頁數: 377
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3031367375
  • ISBN-13: 9783031367373
  • 海外代購書籍(需單獨結帳)

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商品描述

This book provides researchers in the fields of organic chemistry, organometallic chemistry and homogeneous catalysis with an overview of recent developments in the applications of reactions involving carbene and nitrene intermediates directed to the synthesis of heterocyclic compounds. Multiple pathways through which diverse heterocyclic compounds are accessed occur from a variety of carbene and nitrene precursors through C-H/X-H insertions, cycloadditions, ylide transformations, rearrangements, and cascade reactions. Catalytic processes that form metallo-carbenes and nitrenes offer unparalleled chemo-, regio-, and stereo-selectivities. Insights are provided into the scope of these methodologies and the inherent control of catalyst ligands on reaction selectivities.

商品描述(中文翻譯)

本書為有機化學、金屬有機化學及均相催化領域的研究人員提供了有關涉及碳烯和氮烯中間體的反應在合成雜環化合物應用中的最新發展概述。通過各種碳烯和氮烯前驅物,透過 C-H/X-H 插入、環加成、亞胺轉化、重排及級聯反應等多條途徑,可以獲得多樣的雜環化合物。形成金屬碳烯和氮烯的催化過程提供了無與倫比的化學選擇性、區域選擇性和立體選擇性。本書還提供了這些方法學的範疇及催化劑配體對反應選擇性的內在控制的見解。

作者簡介

Michael P. Doyle is the Rita and John Feik Distinguished University Chair in Medicinal Chemistry at the University of Texas at San Antonio. He is a graduate of the College of St. Thomas and Iowa State University, has had academic appointments at undergraduate institutions (Hope College and Trinity University) and graduate universities (University of Arizona and University of Maryland) before taking his current position. He is widely recognized for his research in catalytic methods for metal carbene transformations.
Xinfang Xu is graduated from East China Normal University (bachelor's degree in 2005, and Ph.D. in 2010), then conducted postdoctoral study at University of Maryland with Prof. Michael P. Doyle (2010-2014). In 2014, he started his independent career at Soochow University. He is now a full professor at Sun Yat-sen University, where his research interests include catalytic carbene gem-difunctionalization and cascade reaction, asymmetric catalysis, and bioactivity-oriented heterocycle syntheses.

作者簡介(中文翻譯)

邁克爾·P·道爾(Michael P. Doyle)是德克薩斯州聖安東尼奧大學藥物化學的瑞塔與約翰·費克傑出大學講座教授。他畢業於聖托馬斯學院和愛荷華州立大學,曾在本科院校(霍普學院和三一大學)及研究生院校(亞利桑那大學和馬里蘭大學)擔任學術職位,之後才擔任目前的職位。他因在金屬碳烯轉化的催化方法研究方面而廣受認可。

徐新芳(Xinfang Xu)於2005年獲得華東師範大學學士學位,2010年獲得博士學位,隨後在馬里蘭大學進行道爾教授的博士後研究(2010-2014)。2014年,他在蘇州大學開始了獨立的職業生涯。現在,他是中山大學的正教授,研究興趣包括催化碳烯的gem-雙官能化和級聯反應、不對稱催化以及以生物活性為導向的雜環合成。