Mathematical Models and Computer Simulations for Biomedical Applications

Bretti, Gabriella, Natalini, Roberto, Palumbo, Pasquale

  • 出版商: Springer
  • 出版日期: 2024-08-18
  • 售價: $7,720
  • 貴賓價: 9.5$7,334
  • 語言: 英文
  • 頁數: 257
  • 裝訂: Quality Paper - also called trade paper
  • ISBN: 3031357175
  • ISBN-13: 9783031357176
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

Mathematical modelling and computer simulations are playing a crucial role in the solution of the complex problems arising in the field of biomedical sciences and provide a support to clinical and experimental practices in an interdisciplinary framework.
Indeed, the development of mathematical models and efficient numerical simulation tools is of key importance when dealing with such applications.
Moreover, since the parameters in biomedical models have peculiar scientific interpretations and their values are often unknown, accurate estimation techniques need to be developed for parameter identification against the measured data of observed phenomena. In the light of the new challenges brought by the biomedical applications, computational mathematics paves the way for the validation of the mathematical models and the investigation of control problems.
The volume hosts high-quality selected contributions containing original research results as well as comprehensive papers and survey articles including prospective discussion focusing on some topical biomedical problems. It is addressed, but not limited to: research institutes, academia, and pharmaceutical industries.

商品描述(中文翻譯)

數學建模和計算機模擬在解決生物醫學科學領域中出現的複雜問題方面扮演著至關重要的角色,並在跨學科的框架中為臨床和實驗實踐提供支持。事實上,當處理這類應用時,數學模型的發展和高效的數值模擬工具是關鍵的重要性。此外,由於生物醫學模型中的參數具有特殊的科學解釋,且其值通常未知,因此需要開發準確的估計技術以便根據觀察現象的測量數據進行參數識別。面對生物醫學應用帶來的新挑戰,計算數學為數學模型的驗證和控制問題的研究鋪平了道路。本卷收錄了高品質的選定貢獻,包含原創研究結果以及綜合性論文和調查文章,並包括針對一些當前生物醫學問題的前瞻性討論。該卷的受眾包括但不限於研究機構、學術界和製藥行業。

作者簡介

Gabriella Bretti is a senior researcher at IAC-CNR. Her actual research interests are focused development of mathematical tools including modelling, numerical methods, simulation algorithms and parameter estimation techniques for differential models arising in real applications, with a special focus on biomathematics and cultural heritage.

Roberto Natalini is a mathematician and the Director of the Istituto per le Applicazioni del Calcolo of the National Research Council of Italy. His research themes include: fluid dynamics, road traffic, semiconductors, chemical and biological damage of monuments, biomathematics, game theory in evolutionary dynamics. In the last few years his research has focused on the mathematical models of the organs-on-chip and other experimental settings related to the cells movement.

Luigi Preziosi is full professor of Mathematical Physics at the Politecnico di Torino. His research is essentially devoted to the different aspects of mathematical modelling, from the formulation of models, to their analytic study, simulation and validation. In the last thirty years his attention focused on biomedical applications, including tumour growth, vascular networks, tissue mechanics, cell-environment interactions, cell migration, multiscale aspects in individual based models.

Pasquale Palumbo is an Associate Professor of systems and control theory at the University of Milano-Bicocca, Milan, Italy, and an associate researcher at the Institute of Systems Analysis and Computer Science "A. Ruberti," Italian National Research Council (IASI-CNR), Rome, Italy. His present research focuses on both methodological and application topics, including mathematical modeling and control of the glucose-insulin system, and systems and synthetic biology.

作者簡介(中文翻譯)

Gabriella Bretti 是 IAC-CNR 的高級研究員。她目前的研究興趣集中在數學工具的開發,包括建模、數值方法、模擬算法和參數估計技術,這些工具用於實際應用中的微分模型,特別關注生物數學和文化遺產。

Roberto Natalini 是數學家,也是意大利國家研究委員會計算應用研究所的所長。他的研究主題包括:流體力學、道路交通、半導體、文物的化學和生物損害、生物數學、進化動態中的博弈論。在過去幾年中,他的研究集中在器官芯片的數學模型以及與細胞運動相關的其他實驗設置。

Luigi Preziosi 是都靈理工學院的數學物理全職教授。他的研究主要致力於數學建模的不同方面,從模型的形成到其解析研究、模擬和驗證。在過去三十年中,他的注意力集中在生物醫學應用上,包括腫瘤生長、血管網絡、組織力學、細胞與環境的相互作用、細胞遷移以及基於個體模型的多尺度方面。

Pasquale Palumbo 是意大利米蘭比科卡大學系統與控制理論的副教授,同時也是意大利國家研究委員會 'A. Ruberti' 系統分析與計算機科學研究所的副研究員。他目前的研究集中在方法論和應用主題,包括葡萄糖-胰島素系統的數學建模與控制,以及系統與合成生物學。