Robotic Micromanipulation of Zebrafish Larva

本書為讀者提供了一系列機器人方法，用於操控斑馬魚幼體，這是生物醫學研究和臨床應用中最受歡迎的模式脊椎動物之一。作者利用先進的控制理論、影像處理演算法和人工智慧，建立了一個機器人輔助的自動或半自動斑馬魚幼體目標微操控系統，以滿足不同的實驗需求。所提出的方法具有通用性，並可轉換為操控其他類型的生物物體，例如胚胎或細胞。內容涵蓋了操控斑馬魚幼體的程序，包括平面定位、三維定向、可變形的固定、器官目標微注射、整體生物影像以及斑馬魚幼體群體運動的高通量軌跡追蹤等主題。

《斑馬魚幼體的機器人微操控》以簡單、清晰且易於閱讀的風格撰寫。它是學術研究者和生物醫學操作員的理想參考資料，也是學習機器人技術、控制與系統理論、影像處理、人工智慧和生物醫學工程的學生的寶貴資源。

Songlin Zhuang received a B.E. in automation and a Ph.D. in control science and engineering from the Harbin Institute of Technology, China, in 2014 and 2019, respectively. From 2019 to 2020, he was a Postdoctoral Researcher with the Department of Mechanical and Industrial Engineering at the University of Toronto, Canada. Since October 2020, he has been a Postdoctoral Fellow with the Department of Mechanical Engineering at the University of Victoria, Canada. Dr. Zhuang's research interests include robotic micromanipulation with biomedical and clinical applications and control theories with industrial applications.

Gefei Zhang received a B.E. degree and Ph.D. in control science and engineering from the Harbin Institute of Technology, China, in 2016 and 2022, respectively. He is currently an Assistant Professor with the Research Institute of Intelligent Control and Systems at the Harbin Institute of Technology. His research interests include robotic micromanipulation, image processing, and adaptive robust control.

Xinghu Yu received an M.M. in osteopathic medicine from Jinzhou Medical University, China, and a Ph.D. in control science and engineering from the Harbin Institute of Technology, in 2016 and 2020, respectively. He is currently the Chief Executive Officer of the Ningbo Institute of Intelligent Equipment Technology Co., Ltd., China. He has authored over ten technical papers for conference proceedings and refereed journals, including the IEEE Transactions journals, and has over 20 invention patents. His research interests include switched systems, intelligent control, and biomedical image processing.

Huijun Gao received a Ph.D. in control science and engineering from the Harbin Institute of Technology, China, in 2005. From 2005 to 2007, he was a Postdoctoral Researcher with the Department of Electrical and Computer Engineering at the University of Alberta, Canada. Since 2004, he has been with the Harbin Institute of Technology, where heis currently a Chair Professor and the Director of the Research Institute of Intelligent Control and Systems. His research interests include intelligent and robust control, robotics, mechatronics, and their engineering applications. Dr. Gao is a Vice President of the IEEE Industrial Electronics Society and a Council Member of IFAC. He currently serves and has held editorial positions with several respected international journals, including Editor in Chief of the IEEE/ASME Transactions on Mechatronics, Coeditor in Chief of the IEEE Transactions on Industrial Electronics, and Associate Editor of Automatica, the IEEE Transactions on Cybernetics, and the IEEE Transactions on Industrial Informatics. He is a Fellow of the IEEE and a Distinguished Lecturer of the IEEE Systems, Man, and Cybernetics Society. He is a member of the Academia Europaea.

Dongxu Lei received a B.E. degree in automation and an M.E. degree in control science and engineering from the Harbin Institute of Technology, Harbin, China, in 2018 and 2020, respectively, where he is pursuing a Ph.D. in control science and engineering. His research interests include image processing, data analysis, and control theory.

Mingsi Tong received a Ph.D. in mechatronic engineering from the Harbin Institute of Technology, Harbin, China, in 2016. He also concurrently studied at the National Institute of Standards and Technology, Washington, DC, USA, as a Guest Researcher during his graduate studies. He is an Associate Professor at the School of Mechatronics Engineering, Harbin Institute of Technology. His research interests include machine vision, pattern recognition, and surface metrology.

Weiyang Lin received B.S., M.Sc., and Ph.D. degrees in mechanical engineering from the Harbin Institute of Technology, Harbin, China, in 2006, 2008, and 2014, respectively. He is an Associate Professor with the Research Institute of Intelligent Control and Systems, Harbin Institute of Technology. His research interests include parallel manipulators, robotic motion control, and visual servo control.

Yang Shi received B.Sc. and Ph.D. degrees in mechanical engineering and automatic control from Northwestern Polytechnical University, Xi'an, China, in 1994 and 1998, respectively, and a Ph.D. in electrical and computer engineering from the University of Alberta, Edmonton, AB, Canada, in 2005. From 2005 to 2009, he was an Assistant Professor and Associate Professor in the Department of Mechanical Engineering at the University of Saskatchewan, Saskatoon, SK, Canada. In 2009, he joined the University of Victoria and is now a Professor in the Department of Mechanical Engineering, University of Victoria, Victoria, BC, Canada. His current research interests include networked and distributed systems, model predictive control (MPC), cyber-physical systems (CPS), robotics and mechatronics, navigation and control of autonomous systems (AUV andUAV), and energy system applications. Dr. Shi is a member of the IEEE IES Administrative Committee and the IES Fellow Evaluation Committee during 2017-2019; he is the Chair of the IEEE IES Technical Committee on Industrial Cyber-Physical Systems. Currently, he is Co-Editor-in-Chief for IEEE Transactions on Industrial Electronics; he also serves as Associate Editor for several other journals, including Automatica, IEEE Transactions on Control Systems Technology, IEEE/ASME Transactions on Mechatronics, and IEEE Transactions on Cybernetics. Prof. Shi is the General Chair of the 2019 International Symposium on Industrial Electronics (ISIE) and the 2021 International Conference on Industrial Cyber-Physical Systems (ICPS). He is a Fellow of IEEE, ASME, Engineering Institute of Canada (EIC), and Canadian Society for Mechanical Engineering (CSME), and a registered Professional Engineer in British Columbia, Canada.

Songlin Zhuang於2014年和2019年分別在中國哈爾濱工業大學獲得自動化學士學位和控制科學與工程博士學位。從2019年到2020年，他在加拿大多倫多大學機械與工業工程系擔任博士後研究員。自2020年10月以來，他在加拿大維多利亞大學機械工程系擔任博士後研究員。Zhuang博士的研究興趣包括具有生物醫學和臨床應用的機器人微操控，以及具有工業應用的控制理論。

Gefei Zhang於2016年和2022年分別在中國哈爾濱工業大學獲得控制科學與工程的學士學位和博士學位。他目前是哈爾濱工業大學智能控制與系統研究所的助理教授。他的研究興趣包括機器人微操控、影像處理和自適應穩健控制。

Xinghu Yu於2016年在中國錦州醫科大學獲得骨科醫學碩士學位，並於2020年在哈爾濱工業大學獲得控制科學與工程博士學位。他目前是中國寧波智能設備技術有限公司的首席執行官。他已發表超過十篇技術論文於會議論文集和同行評審期刊，包括IEEE Transactions期刊，並擁有超過20項發明專利。他的研究興趣包括切換系統、智能控制和生物醫學影像處理。

Huijun Gao於2005年在中國哈爾濱工業大學獲得控制科學與工程博士學位。從2005年到2007年，他在加拿大阿爾伯塔大學電氣與計算機工程系擔任博士後研究員。自2004年以來，他一直在哈爾濱工業大學工作，目前擔任講座教授及智能控制與系統研究所所長。他的研究興趣包括智能與穩健控制、機器人技術、機電一體化及其工程應用。Gao博士是IEEE工業電子學會的副會長，也是IFAC的理事會成員。他目前擔任並曾擔任多本國際知名期刊的編輯職位，包括《IEEE/ASME Transactions on Mechatronics》的主編、《IEEE Transactions on Industrial Electronics》的共同主編，以及《Automatica》、《IEEE Transactions on Cybernetics》和《IEEE Transactions on Industrial Informatics》的副編輯。他是IEEE的會士，也是IEEE系統、人類與控制論學會的特聘講師。他是歐洲學院的成員。

Dongxu Lei於2018年和2020年分別在中國哈爾濱工業大學獲得自動化學士學位和控制科學與工程碩士學位，目前正在該校攻讀控制科學與工程博士學位。他的研究興趣包括影像處理、數據分析和控制理論。

Mingsi Tong於2016年在中國哈爾濱工業大學獲得機電工程博士學位。在研究生期間，他還曾在美國華盛頓特區的國家標準與技術研究所擔任客座研究員。他是哈爾濱工業大學機電工程學院的副教授。他的研究興趣包括機器視覺、模式識別和表面計量。

Weiyang Lin於2006年、2008年和2014年分別在中國哈爾濱工業大學獲得機械工程的學士、碩士和博士學位。他是哈爾濱工業大學智能控制與系統研究所的副教授。