Yeasts in Biotechnology and Human Health: Physiological Genomic Approaches
暫譯: 酵母在生物技術與人類健康中的應用:生理基因組方法
Sa-Correia, Isabel
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商品描述
This book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research.
The use of yeasts as experimental eukaryotic models increasingly gained prominence when several Nobel Prizes in Physiology/Medicine and Chemistry were awarded for innovative research, using yeast strains to elucidate molecular mechanisms in a wide range of human physiological processes and diseases, such as autophagy, cell cycle regulation and telomerase activity.
This book offers useful insights for scientists in yeast research, clinical scientists working with yeast infectious models and for industrial researchers using applied microbiology.
商品描述(中文翻譯)
本書探討基於基因組的策略,以提供對酵母在人體健康中的整體理解,以及作為基礎研究或工業生產中的模型生物。使用多種來源的多株酿酒酵母(Saccharomyces cerevisiae)和各種非傳統酵母物種,描述了基本的生物過程、酵母的生物技術利用以及病原控制。它還展示了功能性和比較基因組學以及基因組工程工具的發展如何應用於現代酵母研究。
當幾個諾貝爾生理學/醫學獎和化學獎因創新研究而頒發給使用酵母株來闡明人類生理過程和疾病(如自噬、細胞週期調控和端粒酶活性)的分子機制時,酵母作為實驗真核模型的使用越來越受到重視。
本書為從事酵母研究的科學家、與酵母感染模型合作的臨床科學家以及使用應用微生物學的工業研究人員提供了有用的見解。