Melanoma
暫譯: 黑色素瘤

黑色素瘤是一本關於黑色素瘤主題的前沿綜合參考書籍。其主要目標是提供詳細的學術資訊，廣泛涵蓋該疾病的臨床表現和管理的各個方面，以及對其發病機制和治療的生物學和科學理解。重點主題包括分子診斷的最新突破、靶向治療方法的突破、信號傳導和轉錄途徑的概述，以及重要的爭議問題，如篩檢、早期診斷、哨兵淋巴結活檢和預防策略。總的來說，這本書提供了黑色素瘤領域的前沿和綜合性介紹，由一組國際知名的思想領袖撰寫。

David E. Fisher, MD, PhD, is chief of the Massachusetts General Hospital Department of Dermatology. He also serves as director of Mass General's Cutaneous Biology Research Center, director of the Melanoma Center and as Chair of the MGH Executive Committee on Research. A professor of dermatology and of pediatrics at Harvard Medical School, Dr. Fisher came to Mass General from the Dana-Farber Cancer Institute, where he previously directed the melanoma program. Dr. Fisher's research has focused on understanding the molecular and genetic events which underlie formation of melanoma as well as skin pigmentation. As a clinician, he has worked to translate these understandings into advances in diagnosis, treatment and prevention of human diseases related to the skin and associated disorders.

A graduate of Swarthmore College with a degree in biology and chemistry, Dr. Fisher is also an accomplished concert cellist and graduated from the Curtis Institute of Music in Philadelphia. He received his doctorate under Nobel Laureate Gunter Blobel and Henry Kunkel at Rockefeller University and his medical degree at Cornell University Medical College. Dr. Fisher's specialty training in Medicine, Pediatrics and Oncology were carried out at Dana-Farber Cancer Institute, Boston Children's Hospital, and Brigham and Women's Hospital, Harvard Medical School. His research contributions include elucidation of the pathway through which UV radiation induces pigmentation, identification of MITF as master transcriptional regulator in melanocytes and melanoma oncogene, novel approaches to melanoma treatment and prevention, and discovery of the link between ultraviolet radiation and addictive behaviors.

Boris C. Bastian, MD, received his medical degree from the University of Munich, Germany. He completed his residency in dermatology at the University of Würzburg, Germany. He did a post-doctoral fellowship at the Cancer Genetics Program at the University of California, San Francisco and joined the UCSF faculty in 1999 with appointments in dermatology and pathology. He served as the chair of the pathology department at Memorial Sloan-Kettering Cancer Center and was President of the Society of Melanoma Research from 2010 to 2013. In 2011 he returned to UCSF, where he now leads a research laboratory focused on the genetic underpinnings of skin cancer with the goal of improving disease classification and diagnosis, therapy, and prevention.ng the genetic underpinnings of skin cancer with the goal to improve diagnosis, therapy and prevention.

大衛·E·費舍爾醫學博士，哲學博士，是麻薩諸塞州總醫院皮膚科的主任。他同時擔任麻薩諸塞州總醫院皮膚生物學研究中心的主任、黑色素瘤中心的主任，以及麻薩諸塞州總醫院研究執行委員會的主席。費舍爾博士是哈佛醫學院皮膚科和小兒科的教授，他從丹娜法伯癌症研究所來到麻薩諸塞州總醫院，之前在那裡負責黑色素瘤計劃。費舍爾博士的研究專注於理解導致黑色素瘤形成以及皮膚色素沉著的分子和遺傳事件。作為一名臨床醫生，他致力於將這些理解轉化為在皮膚相關疾病及其相關疾病的診斷、治療和預防方面的進展。

費舍爾博士畢業於斯沃斯莫爾學院，獲得生物學和化學學位，他也是一位出色的音樂會大提琴家，畢業於費城的柯蒂斯音樂學院。他在洛克菲勒大學的諾貝爾獎得主根特·布洛貝爾和亨利·昆克爾的指導下獲得博士學位，並在康奈爾大學醫學院獲得醫學學位。費舍爾博士在丹娜法伯癌症研究所、波士頓兒童醫院和哈佛醫學院的布萊根和婦女醫院接受了內科、小兒科和腫瘤學的專科訓練。他的研究貢獻包括闡明紫外線輻射誘導色素沉著的途徑、識別MITF作為黑色素細胞和黑色素瘤癌基因的主要轉錄調控因子、黑色素瘤治療和預防的新方法，以及發現紫外線輻射與成癮行為之間的聯繫。

鮑里斯·C·巴斯蒂安醫學博士，獲得德國慕尼黑大學的醫學學位。他在德國維爾茨堡大學完成皮膚科的住院醫師訓練。他在加州大學舊金山分校的癌症遺傳學計劃進行了博士後研究，並於1999年加入舊金山大學的教職，擔任皮膚科和病理學的職位。他曾擔任紀念斯隆-凱特琳癌症中心病理學系的主任，並於2010年至2013年擔任黑色素瘤研究學會的會長。2011年，他回到舊金山大學，現在領導一個專注於皮膚癌遺傳基礎的研究實驗室，旨在改善疾病的分類和診斷、治療和預防。