Generic: The Unbranding of Modern Medicine (Hardcover)
暫譯: 現代醫學的去品牌化 (精裝版)
Jeremy A. Greene
- 出版商: Johns Hopkins University Press
- 售價: $1,610
- 貴賓價: 9.5 折 $1,530
- 語言: 英文
- 頁數: 368
- 裝訂: Hardcover
- ISBN: 1421414937
- ISBN-13: 9781421414935
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商品描述
Generic drugs are now familiar objects in clinics, drugstores, and households around the world. We like to think of these tablets, capsules, patches, and ointments as interchangeable with their brand-name counterparts: why pay more for the same? And yet they are not quite the same. They differ in price, in place of origin, in color, shape, and size, in the dyes, binders, fillers, and coatings used, and in a host of other ways. Claims of generic equivalence, as physician-historian Jeremy Greene reveals in this gripping narrative, are never based on being identical to the original drug in all respects, but in being the same in all ways that matter.
How do we know what parts of a pill really matter? Decisions about which differences are significant and which are trivial in the world of therapeutics are not resolved by simple chemical or biological assays alone. As Greene reveals in this fascinating account, questions of therapeutic similarity and difference are also always questions of pharmacology and physiology, of economics and politics, of morality and belief.
Generic is the first book to chronicle the social, political, and cultural history of generic drugs in America. It narrates the evolution of the generic drug industry from a set of mid-twentieth-century "schlock houses" and "counterfeiters" into an agile and surprisingly powerful set of multinational corporations in the early twenty-first century.
The substitution of bioequivalent generic drugs for more expensive brand-name products is a rare success story in a field of failed attempts to deliver equivalent value in health care for a lower price. Greene’s history sheds light on the controversies shadowing the success of generics: problems with the generalizability of medical knowledge, the fragile role of science in public policy, and the increasing role of industry, marketing, and consumer logics in late-twentieth-century and early twenty-first century health care.
商品描述(中文翻譯)
泛用藥物現在已成為全球診所、藥局和家庭中熟悉的物品。我們喜歡將這些藥片、膠囊、貼片和軟膏視為與其品牌名稱對應物可互換的:為什麼要為相同的東西支付更多?然而,它們並不完全相同。它們在價格、產地、顏色、形狀和大小、所使用的染料、黏合劑、填充劑和包衣等方面存在差異,還有許多其他方面。正如醫生兼歷史學家 Jeremy Greene 在這個引人入勝的敘述中揭示的,泛用藥物的等效性聲明從來不是基於在所有方面都與原始藥物相同,而是在所有重要的方面都是相同的。
我們如何知道藥丸的哪些部分真的重要?在治療領域,關於哪些差異是重要的,哪些是微不足道的決策,並不是僅僅通過簡單的化學或生物檢測就能解決的。正如 Greene 在這個引人入勝的敘述中所揭示的,治療相似性和差異性問題始終也是藥理學和生理學、經濟學和政治學、道德和信仰的問題。
《泛用藥物》是第一本記錄美國泛用藥物社會、政治和文化歷史的書籍。它敘述了泛用藥物產業從二十世紀中期的一系列「劣質藥廠」和「偽造者」演變為二十一世紀初一組靈活且出乎意料地強大的跨國公司的過程。
用生物等效的泛用藥物替代更昂貴的品牌產品是一個在試圖以更低價格提供等值醫療服務的失敗嘗試中,少數成功的故事之一。Greene 的歷史揭示了圍繞泛用藥物成功的爭議:醫學知識的普遍性問題、科學在公共政策中的脆弱角色,以及在二十世紀末和二十一世紀初的醫療保健中,產業、市場營銷和消費者邏輯日益增長的角色。