Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R (Hardcover)
暫譯: 計算生物學中的組合模式匹配演算法:使用 Perl 和 R (精裝版)

Gabriel Valiente

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商品描述

Emphasizing the search for patterns within and between biological sequences, trees, and graphs, Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R shows how combinatorial pattern matching algorithms can solve computational biology problems that arise in the analysis of genomic, transcriptomic, proteomic, metabolomic, and interactomic data. It implements the algorithms in Perl and R, two widely used scripting languages in computational biology.

 

The book provides a well-rounded explanation of traditional issues as well as an up-to-date account of more recent developments, such as graph similarity and search. It is organized around the specific algorithmic problems that arise when dealing with structures that are commonly found in computational biology, including biological sequences, trees, and graphs. For each of these structures, the author makes a clear distinction between problems that arise in the analysis of one structure and in the comparative analysis of two or more structures. He also presents phylogenetic trees and networks as examples of trees and graphs in computational biology.

 

This book supplies a comprehensive view of the whole field of combinatorial pattern matching from a computational biology perspective. Along with thorough discussions of each biological problem, it includes detailed algorithmic solutions in pseudo-code, full Perl and R implementation, and pointers to other software, such as those on CPAN and CRAN.

商品描述(中文翻譯)

強調在生物序列、樹和圖之間尋找模式的《使用 Perl 和 R 的計算生物學中的組合模式匹配演算法》展示了組合模式匹配演算法如何解決在基因組、轉錄組、蛋白質組、代謝組和互作組數據分析中出現的計算生物學問題。它在 Perl 和 R 這兩種在計算生物學中廣泛使用的腳本語言中實現了這些演算法。

本書對傳統問題提供了全面的解釋,並對更近期的發展,如圖相似性和搜索,進行了最新的說明。內容圍繞在處理計算生物學中常見結構時出現的特定演算法問題進行組織,包括生物序列、樹和圖。對於這些結構中的每一種,作者清楚地區分了在分析單一結構時出現的問題與在比較分析兩個或多個結構時出現的問題。他還以系統發育樹和網絡作為計算生物學中樹和圖的例子。

本書從計算生物學的角度提供了組合模式匹配整個領域的綜合視角。除了對每個生物問題進行深入討論外,還包括詳細的演算法解決方案的偽代碼、完整的 Perl 和 R 實現,以及指向其他軟體的參考,例如 CPAN 和 CRAN 上的軟體。