Organic Chemistry, 7/e (Paperback)

Description
Organic Chemistry, Seventh Edition, continues the successful student-oriented approach used in prior editions. This text uses less prose and more diagrams and bulleted summaries for today’s students, who rely more heavily on visual imagery to learn than ever before. Each topic is broken down into small chunks of information that are more manageable and easily learned.

Organic chemistry is a dynamic subject that is continually refined as new facts are determined. Each year, novel compounds are discovered, and new drugs are marketed, and these compounds replace older examples to illustrate particular concepts. In this edition, for example, every effort has been made to include content on COVID-19.

The text is strengthened by its offering in ALEKS, now featuring Custom Question Authoring, Video Assignments, Virtual Labs, and more!

The Basic Features
Organic Chemistry, seventh edition, continues the successful student-oriented approach used in prior editions. This text uses less prose and more diagrams and bulleted summaries for today's students, who rely more heavily on visual imagery to learn than ever before. is broken down into small chunks of information that are more manageable and easily learned. Sample Problems illustrate stepwise problem solving, and relevant examples from everyday life are used to illustrate topics. New concepts are introduced one at a time so that the basic themes are kept in focus.

The organization of this text provides the student with a logical and accessible approach to an intense and fascinating subject. The text begins with a healthy dose of review material in Chapters 1 and 2 to ensure that students have a firm grasp of the fundamentals. Stereochemistry, the three-dimensional structure of molecules, is introduced early (Chapter 5) and reinforced often. Certain reaction types with unique characteristics and terminology are grouped together. These
include acid-base reactions (Chapter 2), oxidation and reduction (Chapters 12 and 17), reactions of organometallic reagents (Chapters 17 and 24), and radical reactions (Chapter 13). Each chapter ends with a Chapter Review, end-of-chapter summaries that succinctly organize the main concepts and reactions.

New to this Edition
Students sometimes ask me if the facts of organic chemistry have significantly changed since the last edition. While the basic principles remain the same--carbon forms four bonds in stable compounds and oppositely charged species attract each other--organic chemistry is a dynamic subject that is continually refined as new facts are determined, and new editions reflect current understanding. Each year, novel compounds are discovered and new drugs are
marketed, and these compounds replace older examples to illustrate particular concepts. In this edition, for example, every effort has been made to include content on COVID-19, the devastating disease responsible for the worldwide pandemic that began in late 2019. This material is included in the Prologue, Problems 3.60 and 29.25, and Sections 19.4, 20.5, and 28.9.

General
Other New Coverage
Several sections include new material.

• Problems In response to reviewer feedback, the level of difficulty in some Sample Problems has been increased, so that students can more readily tackle related, more challenging end-of-chapter problems. There are now more in-chapter problems, either new to this edition or moved from the end-of-chapter material, to give students more immediate practice on the topics they have just learned. In all, this edition contains more than 300 new problems.
• Multiple-Choice Self-Test Each chapter now contains a Multiple-Choice Self-Test following the Chapter Review, which gives students added practice on key principles prior to solving the end-of-chapter problems. Answers to the self-test are given at the end of each chapter.
• Chapters Two new chapters are added to this edition and three chapters are now available in the eBook and for customizable versions.
  • Chapter 28 provides an in-depth discussion of the structure and properties of the nucleic acids DNA and RNA. Three key processes are presented: replication--how DNA makes copies of itself; transcription--how the genetic information in DNA is passed onto RNA; and translation--how the coded genetic information in RNA is used to synthesize proteins. The chapter concludes with discussions of manipulating DNA in the laboratory and how viruses act.
  • Chapter 30 focuses on the biochemical reactions involved in metabolism. The discussion centers on three components: the breakdown of fats, the metabolism of the carbohydrate glucose to the three-carbon unit pyruvate by glycolysis, and the citric acid cycle, a key cyclic metabolic pathway used for amino acids, carbohydrates, and fats. Chapters 1-28 are available in the print edition of Organic Chemistry, and Chapters 29 (Lipids), 30 (Metabolism), and 31 (Synthetic Polymers) are available in the eBook and for customizable versions.
• Section 7.4 contains material on the prevalence of fluoro and trifluoromethy| groups in several new drugs.
• Three examples of recently approved drugs that contain epoxides or ethers, along with other functional groups, have been added to Section 9.5B.
• Section B.4 has been completely reorganized so that infrared spectra of related compounds can be more easily compared.
• In NMR spectroscopy, the spin-spin splitting discussion in Section C.8 has been revised and a new example is used in Figure C.8 to better illustrate this concept.
• Heterocyclic aromatic compounds are moved into their own section (15.9), and material on the aromatic bases in DNA has been added.
• Figures 17.2-17.5 have all been updated with new molecules and examples using drugs and marine natural products.
• A new Sample Problem 184 on distinguishing ethers and acetals in a complex molecule has been added.
• New material on biological enols is now in Section 21.2B.
• In Chapter 22, two sections have been added: Section 22.1B on the retro-aldol reaction and Section 22.2C on enantioselective aldol reactions and the 2021 Nobel Prize in Chemistry.
• Chapter 24 now contains the Stille coupling reaction in Section 24.4.
• Section 27.10 on enzymes has been added to Chapter 27.
• New material has been added to Chapter 31 to reflect recent advances on biodegradable polymers and the use of polymers in controlled drug release.