Practical Guide to ChIP-seq Data Analysis (Focus Computational Biology Series)
暫譯: ChIP-seq 數據分析實用指南(聚焦計算生物學系列)
Borbala Mifsud, Kathi Zarnack, Anaïs F Bardet
- 出版商: CRC
- 出版日期: 2018-11-05
- 售價: $2,810
- 貴賓價: 9.5 折 $2,670
- 語言: 英文
- 頁數: 112
- 裝訂: Hardcover
- ISBN: 1138596523
- ISBN-13: 9781138596528
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相關分類:
Data Science
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商品描述
Chromatin immunoprecipitation sequencing (ChIP-seq), which maps the genome-wide localization patterns of transcription factors and epigenetic marks, is among the most widely used methods in molecular biology. Practical Guide to ChIP-seq Data Analysis will guide readers through the steps of ChIP-seq analysis: from quality control, through peak calling, to downstream analyses. It will help experimental biologists to design their ChIP-seq experiments with the analysis in mind, and to perform the basic analysis steps themselves. It also aims to support bioinformaticians to understand how the data is generated, what the sources of biases are, and which methods are appropriate for different analyses.
商品描述(中文翻譯)
染色質免疫沉澱測序(Chromatin immunoprecipitation sequencing, ChIP-seq)是映射轉錄因子和表觀遺傳標記在全基因組定位模式的最廣泛使用的方法之一。《ChIP-seq數據分析實用指南》(Practical Guide to ChIP-seq Data Analysis)將指導讀者完成ChIP-seq分析的步驟:從質量控制、峰值呼叫到下游分析。它將幫助實驗生物學家設計考慮到分析的ChIP-seq實驗,並自行執行基本的分析步驟。它的目標還是支持生物資訊學家理解數據是如何生成的、偏差的來源是什麼,以及哪些方法適合不同的分析。