Reverse Engineering of Regulatory Networks (監管網絡的逆向工程)
Mandal, Sudip
- 出版商: Humana Press
- 出版日期: 2024-10-08
- 售價: $7,030
- 貴賓價: 9.5 折 $6,679
- 語言: 英文
- 頁數: 327
- 裝訂: Quality Paper - also called trade paper
- ISBN: 1071634631
- ISBN-13: 9781071634639
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商品描述
This volume details the development of updated dry lab and wet lab based methods for the reconstruction of Gene regulatory networks (GRN). Chapters guide readers through culprit genes, in-silico drug discovery techniques, genome-wide ChIP-X data, high-Throughput Transcriptomic Data Exome Sequencing, Next-Generation Sequencing, Fuorescence Spectroscopy, data analysis in Bioinformatics, Computational Biology, and S-system based modeling of GRN. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Reverse Engineering of Regulatory Networks aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
商品描述(中文翻譯)
本卷詳細介紹了更新的乾實驗室和濕實驗室方法,用於重建基因調控網絡(Gene regulatory networks, GRN)。各章節引導讀者了解相關的致病基因、in-silico 藥物發現技術、全基因組 ChIP-X 數據、高通量轉錄組數據、外顯子測序、下一代測序、螢光光譜學、生物資訊學中的數據分析、計算生物學,以及基於 S-system 的 GRN 建模。該書以成功的 Methods in Molecular Biology 系列格式撰寫,各章節包括對其主題的介紹、所需材料和試劑的清單、逐步的可重複實驗室操作流程,以及關於故障排除和避免已知陷阱的關鍵提示。
《調控網絡的逆向工程》權威且前沿,旨在成為新研究者和專家擴展知識的有用且實用的指南。