Antifungal Therapy, Second Edition
暫譯: 抗真菌療法（第二版）

這本新版本的《抗真菌治療》旨在為忙碌的醫生提供簡明、實用的必要資訊，這些醫生包括感染病專科醫生、移植外科醫生、皮膚科醫生和重症醫學醫生，以及對抗真菌治療現狀感興趣的基礎科學家和製藥公司研究人員。它提供了有關抗真菌治療的相關問題的全面、最新的概述，包括臨床真菌學的基礎、各種感染的管理見解、基於證據的治療建議，以及總結目前可用的藥物動力學數據的有用表格。

主要特點

- 提供有關抗真菌藥物的給藥、劑量和藥理學的有用資訊，這些在臨床實踐中可能難以使用
- 包含常見的臨床問題與解答，以突顯經常遇到的病人問題
- 除了抗真菌治療外，還涵蓋臨床真菌學的基本知識，以創建全面的參考資料
- 以全彩插圖和臨床照片呈現概念
- 提供詳細的治療建議證據

Mahmoud A. Ghannoum, PhD, MBA, FIDSA, FAAM joined Case Western Reserve University and University Hospitals Case Medical Center in 1996 from prior positions at the UCLA School of Medicine and Kuwait University. Dr. Ghannoum has spent his entire academic career studying medically important fungi encompassing different fungal pathogens including Candida, Aspergillus, and Cryptococcus, the major causes of fungal infections. He has published more than 350 peer-reviewed articles addressing various aspects of superficial and systemic fungal infections. More recently, he published the first study describing the oral mycobiome of healthy individuals. He has published extensively in the area of fungal pathogenesis with special focus on virulence factors including phospholipase B, germination, adhesion, and biofilm formation, both in vitro and in vivo. Dr. Ghannoum is a professor and director of the Center for Medical Mycology at Case Western Reserve University and University Hospitals Case Medical Center. This center of excellence, which he directs, is a multidisciplinary center that combines basic and translational research investigating fungi from the test tube to the bedside. He has performed several studies investigating the mechanisms underlying Candida pathogenesis. He is the recipient of the Freedom to Discover Award from Bristol- Myers Squibb and the Rhoda Benham Award from the Medical Mycological Society of the Americas. He served as a chairman of the Subcommittee on Antifungal Susceptibility Testing, Clinical Laboratory Standards Institute, and was selected as a "Most Interesting Person" by Cleveland Magazine in 2013. Dr. Ghannoum is an entrepreneur-scientist who has launched a number of companies focusing on the treatment of biofilm infections and microbial dysbiosis as it relates to gut health. He coined the term 'Mycobiome'.

John R. Perfect, MD, is James B. Duke Professor of Medicine at Duke University Medical Center, a faculty member of the Duke University Interdisciplinary Program in Genetics, and director of the Duke University Mycology Research Unit. He is chief of the Division of Infectious Diseases in the Department of Medicine at Duke Medical Center. Dr. Perfect is a diplomat of the American Board of Internal Medicine and American Board of Infectious Diseases. After receiving an undergraduate degree in biology from Wittenberg University, Dr. Perfect went on to receive a medical degree from the Medical College of Ohio at Toledo. He then completed an internship at the Riverside Methodist Hospital in Columbus, Ohio; a residency in internal medicine at the University of Michigan Medical Center in Ann Arbor; and a fellowship in infectious diseases at Duke University Medical Center. He is a fellow of the American Society for Microbiology and the Infectious Diseases Society of America. Dr. Perfect is also a fellow of the American Association for Advancement of Science and member of International Society for Human and Animal Mycology, and Immunocompromised Host Society (ISHAM). He is president of the Mycoses Study Group and Educational Research Consortium and president-elect of ISHAM. Dr. Perfect has served on numerous committees and advisory boards. He received the Rhoda Benham Award from Medical Mycology Society of the Americas and the Lucille Georg Award from ISHAM. Dr. Perfect's research interests focus on the understanding of fungal pathogenesis through the study of Cryptococcus neoformans as well as clinical studies on the epidemiology, diagnosis, and management of invasive mycoses.

Mahmoud A. Ghannoum，博士，MBA，FIDSA，FAAM，自1996年起加入凱斯西儲大學及凱斯醫療中心，之前曾在加州大學洛杉磯分校醫學院及科威特大學任職。Ghannoum博士在其整個學術生涯中專注於研究醫學上重要的真菌，包括主要引起真菌感染的病原體如Candida、Aspergillus和Cryptococcus。他已發表超過350篇經過同行評審的文章，探討各種表淺及系統性真菌感染的不同面向。最近，他發表了第一項描述健康個體口腔真菌組的研究。他在真菌致病學領域的研究廣泛，特別關注於毒力因子，包括磷脂酶B、萌發、黏附及生物膜形成，無論是在in vitro還是in vivo的研究中。Ghannoum博士是凱斯西儲大學及凱斯醫療中心醫學真菌學中心的教授及主任。他所領導的這個卓越中心是一個多學科中心，結合基礎及轉化研究，從試管到臨床床邊研究真菌。他進行了多項研究，探討Candida致病機制。他獲得了百時美施貴寶的自由探索獎及美洲醫學真菌學會的Rhoda Benham獎。他曾擔任臨床實驗室標準協會抗真菌敏感性測試小組的主席，並於2013年被《克里夫蘭雜誌》選為「最有趣的人」。Ghannoum博士是一位企業家科學家，創立了多家公司，專注於生物膜感染及微生物失調與腸道健康的治療。他創造了「Mycobiome」這個術語。

John R. Perfect，醫學博士，是杜克大學醫學中心的詹姆斯·B·杜克醫學教授，杜克大學遺傳學跨學科計畫的教職成員，以及杜克大學真菌學研究單位的主任。他是杜克醫療中心內科部傳染病科的主任。Perfect博士是美國內科醫學委員會及美國傳染病委員會的外交官。Perfect博士在維滕堡大學獲得生物學學士學位後，進一步在俄亥俄州托萊多的醫學學院獲得醫學學位。隨後，他在俄亥俄州哥倫布的河濱衛理醫院完成實習，在密西根大學醫療中心完成內科住院醫師訓練，並在杜克大學醫療中心完成傳染病的研究員訓練。他是美國微生物學會及美國傳染病學會的會員。Perfect博士也是美國科學促進協會的會員，並且是國際人類與動物真菌學會及免疫抑制宿主學會（ISHAM）的會員。他是真菌病研究小組及教育研究聯盟的主席，並且是ISHAM的當選主席。Perfect博士曾在多個委員會及諮詢委員會任職。他獲得了美洲醫學真菌學會的Rhoda Benham獎及ISHAM的Lucille Georg獎。Perfect博士的研究興趣集中在通過研究Cryptococcus neoformans來理解真菌致病機制，以及對侵襲性真菌病的流行病學、診斷及管理的臨床研究。